Effects of Oxidative Stress on the Solubility of HRD1, a Ubiquitin Ligase Implicated in Alzheimer’s Disease

ER Stress-Mediated Apoptotic Pathway Induced by Aβ Peptide Requires the Presence of Functional Mitochondria

(2017) Rui O. Costa et al.   JOURNAL OF ALZHEIMERS DISEASE

Possible Involvement of Ubiquitin Ligase HRD1 Insolubilization in Amyloid β Generation

(2012) Masayuki Kaneko et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Hrd1 Facilitates Tau Degradation and Promotes Neuron Survival

(2012) Y.X. Shen et al.   CURRENT MOLECULAR MEDICINE

Inactivation of Bcl-2 through IκB kinase (IKK)-dependent phosphorylation mediates apoptosis upon exposure to 4-hydroxynonenal (HNE)

(2012) Cagri Bodur et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Early Induction of Oxidative Stress in Mouse Model of Alzheimer Disease with Reduced Mitochondrial Superoxide Dismutase Activity

(2012) Hyun-Pil Lee et al.   PLoS One

Expression of the Ubiquitin Ligase HRD1 in Neural Stem/Progenitor Cells of the Adult Mouse Brain

(2011) Koichi Kawada et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

HRD1 and UBE2J1 target misfolded MHC class I heavy chains for endoplasmic reticulum-associated degradation

(2011) Marian L. Burr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Soluble amyloid  -protein dimers isolated from Alzheimer cortex directly induce Tau hyperphosphorylation and neuritic degeneration

(2011) M. Jin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of cell cycle arrest and DNA damage by the HDAC inhibitor panobinostat (LBH589) and the lipid peroxidation end product 4-hydroxynonenal in prostate cancer cells

(2010) Piergiorgio Pettazzoni et al.   FREE RADICAL BIOLOGY AND MEDICINE

Loss of HRD1-Mediated Protein Degradation Causes Amyloid Precursor Protein Accumulation and Amyloid-  Generation

(2010) M. Kaneko et al.   JOURNAL OF NEUROSCIENCE

Correlation Between Decrease in Protein Levels of Ubiquitin Ligase HRD1 and Amyloid-β Production

(2010) Ryo Saito et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

The ubiquitin ligase Hrd1 promotes degradation of the Z variant alpha 1-antitrypsin and increases its solubility

(2010) Haiping Wang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

The Unfolded Protein Response Is Activated in Pretangle Neurons in Alzheimer's Disease Hippocampus

(2009) Jeroen J.M. Hoozemans et al.   AMERICAN JOURNAL OF PATHOLOGY

Cortical microinfarcts in Alzheimerʼs disease and subcortical vascular dementia

(2009) Yoko Okamoto et al.   NEUROREPORT

4-Hydroxy-2-Nonenal Induces Mitochondrial Dysfunction and Aberrant Axonal Outgrowth in Adult Sensory Neurons that Mimics Features of Diabetic Neuropathy

(2009) Eli Akude et al.   NEUROTOXICITY RESEARCH

Amyloid Precursor Protein Trafficking, Processing, and Function

(2008) Gopal Thinakaran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Immunohistochemical localization of a ubiquitin ligase HRD1 in murine brain

(2008) Tomohiro Omura et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Novel Functions of Ubiquitin Ligase HRD1 With Transmembrane and Proline-Rich Domains

(2008) Tomohiro Omura et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES