Slick Potassium Channels Control Pain and Itch in Distinct Populations of Sensory and Spinal Neurons in Mice

Neural Mechanisms of Itch

(2020) Mark Lay et al.   Annual Review of Neuroscience

Heat detection by the TRPM2 ion channel

(2020) Bruno Vilar et al.   NATURE

Central circuit mechanisms of itch

(2020) Xiao-Jun Chen et al.   Nature Communications

Central Nervous System Targets: Inhibitory Interneurons in the Spinal Cord

(2020) David I Hughes et al.   Neurotherapeutics

Somatostatin 2 Receptors in the Spinal Cord Tonically Restrain Thermogenic, Cardiac and Other Sympathetic Outflows

(2019) Belinda R. Bowman et al.   Frontiers in Neuroscience

Cold sensing by NaV1.8-positive and NaV1.8-negative sensory neurons

(2019) A. P. Luiz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spinal somatostatin-positive interneurons transmit chemical itch

(2019) Mahar Fatima et al.   PAIN

Calretinin positive neurons form an excitatory amplifier network in the spinal cord dorsal horn

(2019) Kelly M Smith et al.   eLife

Spinal Circuits for Touch, Pain, and Itch

(2018) Stephanie C. Koch et al.   Annual Review of Physiology

Neuronal atlas of the dorsal horn defines its architecture and links sensory input to transcriptional cell types

(2018) Martin Häring et al.   NATURE NEUROSCIENCE

Circuit dissection of the role of somatostatin in itch and pain

(2018) Jing Huang et al.   NATURE NEUROSCIENCE

A TRP channel trio mediates acute noxious heat sensing

(2018) Ine Vandewauw et al.   NATURE

International Union of Basic and Clinical Pharmacology. CV. Somatostatin Receptors: Structure, Function, Ligands, and New Nomenclature

(2018) Thomas Günther et al.   PHARMACOLOGICAL REVIEWS

Oxytocin can regulate myometrial smooth muscle excitability by inhibiting the Na+ -activated K+ channel, Slo2.1

(2018) Juan J. Ferreira et al.   JOURNAL OF PHYSIOLOGY-LONDON

Identification of Two Classes of Somatosensory Neurons That Display Resistance to Retrograde Infection by Rabies Virus

(2017) Gioele W. Albisetti et al.   JOURNAL OF NEUROSCIENCE

K Ca 3.1 channels modulate the processing of noxious chemical stimuli in mice

(2017) Ruirui Lu et al.   NEUROPHARMACOLOGY

Heteromeric Slick/Slack K+ channels show graded sensitivity to cell volume changes

(2017) Maria A. Tejada et al.   PLoS One

The TRPM2 ion channel is required for sensitivity to warmth

(2016) Chun-Hsiang Tan et al.   NATURE

Semi-intact ex vivo approach to investigate spinal somatosensory circuits

(2016) Junichi Hachisuka et al.   eLife

Slack Channels Expressed in Sensory Neurons Control Neuropathic Pain in Mice

(2015) R. Lu et al.   JOURNAL OF NEUROSCIENCE

Dorsal Horn Circuits for Persistent Mechanical Pain

(2015) Cedric Peirs et al.   NEURON

Knockout of Slo2.2 enhances itch, abolishes KNa current, and increases action potential firing frequency in DRG neurons

(2015) Pedro L Martinez-Espinosa et al.   eLife

Piezo2 is the major transducer of mechanical forces for touch sensation in mice

(2014) Sanjeev S. Ranade et al.   NATURE

Regulating excitability of peripheral afferents: emerging ion channel targets

(2014) Stephen G Waxman et al.   NATURE NEUROSCIENCE

Unbiased classification of sensory neuron types by large-scale single-cell RNA sequencing

(2014) Dmitry Usoskin et al.   NATURE NEUROSCIENCE

Peripheral thermosensation in mammals

(2014) Joris Vriens et al.   NATURE REVIEWS NEUROSCIENCE

Dynorphin Acts as a Neuromodulator to Inhibit Itch in the Dorsal Horn of the Spinal Cord

(2014) Adam P. Kardon et al.   NEURON

Opening paths to novel analgesics: the role of potassium channels in chronic pain

(2014) Christoforos Tsantoulas et al.   TRENDS IN NEUROSCIENCES

Somatostatin receptors: From signaling to clinical practice

(2013) Marily Theodoropoulou et al.   FRONTIERS IN NEUROENDOCRINOLOGY

A Quantitative Study of Inhibitory Interneurons in Laminae I-III of the Mouse Spinal Dorsal Horn

(2013) Erika Polgár et al.   PLoS One

A Novel Behavioral Assay for Measuring Cold Sensation in Mice

(2012) Daniel S. Brenner et al.   PLoS One

Resolving TRPV1- and TNF- -Mediated Spinal Cord Synaptic Plasticity and Inflammatory Pain with Neuroprotectin D1

(2011) C.-K. Park et al.   JOURNAL OF NEUROSCIENCE

TRPM3 Is a Nociceptor Channel Involved in the Detection of Noxious Heat

(2011) Joris Vriens et al.   NEURON

The majority of myelinated and unmyelinated sensory nerve fibers that innervate bone express the tropomyosin receptor kinase A

(2011) G. Castañeda-Corral et al.   NEUROSCIENCE

Nociceptors: the sensors of the pain pathway

(2010) Adrienne E. Dubin et al.   JOURNAL OF CLINICAL INVESTIGATION

VGLUT2-Dependent Glutamate Release from Nociceptors Is Required to Sense Pain and Suppress Itch

(2010) Yang Liu et al.   NEURON

Loss of Inhibitory Interneurons in the Dorsal Spinal Cord and Elevated Itch in Bhlhb5 Mutant Mice

(2010) Sarah E. Ross et al.   NEURON

Cellular and Molecular Mechanisms of Pain

(2009) Allan I. Basbaum et al.   CELL

The N-Terminal Domain of Slack Determines the Formation and Trafficking of Slick/Slack Heteromeric Sodium-Activated Potassium Channels

(2009) H. Chen et al.   JOURNAL OF NEUROSCIENCE