Generic Plug-and-Play Strategy for High-Throughput Analysis of PTM-Mediated Protein Complexes

Spatiotemporal profiling of cytosolic signaling complexes in living cells by selective proximity proteomics

(2021) Mi Ke et al.   Nature Communications

A tri-functional amino acid enables mapping of binding sites for posttranslational-modification-mediated protein-protein interactions

(2021) Jianwei Lin et al.   MOLECULAR CELL

A System-Wide Spatiotemporal Characterization of ErbB Receptor Complexes by Subcellular Fractionation Integrated Quantitative Mass Spectrometry

(2021) Shujuan Wang et al.   ANALYTICAL CHEMISTRY

Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D

(2020) Susan A. Kennedy et al.   Nature Communications

High-Throughput and Integrated Chemical Proteomic Approach for Profiling Phosphotyrosine Signaling Complexes

(2020) Qian Kong et al.   ANALYTICAL CHEMISTRY

Time-resolved protein activation by proximal decaging in living systems

(2019) Jie Wang et al.   NATURE

High-Throughput Phosphotyrosine Protein Complexes Screening by Photoaffinity-Engineered Protein Scaffold-Based Forward-Phase Protein Array

(2019) Zhendong Zheng et al.   ANALYTICAL CHEMISTRY

Proteomic analysis of NCK1/2 adaptors uncovers paralog-specific interactions that reveal a new role for NCK2 in cell abscission during cytokinesis.

(2018) Kévin Jacquet et al.   MOLECULAR & CELLULAR PROTEOMICS

HATRIC-based identification of receptors for orphan ligands

(2018) Nadine Sobotzki et al.   Nature Communications

Proteomic identification of protein tyrosine phosphatase and substrate interactions in living mammalian cells by genetic encoding of irreversible enzyme inhibitors

(2018) Hongting Tang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Photoaffinity-engineered protein scaffold for systematically exploring native phosphotyrosine signaling complexes in tumor samples

(2018) Bizhu Chu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetically Encoded Photoaffinity Histone Marks

(2017) Xiao Xie et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Site-specific azide-acetyllysine photochemistry on epigenetic readers for interactome profiling

(2017) Babu Sudhamalla et al.   Chemical Science

Enhanced Purification of Ubiquitinated Proteins by Engineered Tandem Hybrid Ubiquitin-binding Domains (ThUBDs)

(2016) Yuan Gao et al.   MOLECULAR & CELLULAR PROTEOMICS

Epigenetic silencing by the HUSH complex mediates position-effect variegation in human cells

(2015) I. A. Tchasovnikarova et al.   SCIENCE

A General Molecular Affinity Strategy for Global Detection and Proteomic Analysis of Lysine Methylation

(2013) Kaitlyn E. Moore et al.   MOLECULAR CELL

A Method for Systematic Mapping of Protein Lysine Methylation Identifies Functions for HP1β in DNA Damage Response

(2013) Huadong Liu et al.   MOLECULAR CELL

To fuse or not to fuse: What is your purpose?

(2013) Mark R. Bell et al.   PROTEIN SCIENCE

Molecular Mechanisms of SH2- and PTB-Domain-Containing Proteins in Receptor Tyrosine Kinase Signaling

(2013) M. J. Wagner et al.   Cold Spring Harbor Perspectives in Biology

SRC Homology 2 Domain Binding Sites in Insulin, IGF-1 and FGF receptor mediated signaling networks reveal an extensive potential interactome

(2012) Bernard A Liu et al.   Cell Communication and Signaling

RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites

(2012) Frédérick A Mallette et al.   EMBO JOURNAL

Quantitative Chemical Proteomics Approach To Identify Post-translational Modification-Mediated Protein–Protein Interactions

(2012) Xiang Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct identification of ligand-receptor interactions on living cells and tissues

(2012) Andreas P Frei et al.   NATURE BIOTECHNOLOGY

Examining post-translational modification-mediated protein-protein interactions using a chemical proteomics approach

(2012) Xiang Li et al.   PROTEIN SCIENCE

Superbinder SH2 Domains Act as Antagonists of Cell Signaling

(2012) T. Kaneko et al.   Science Signaling

Post-translational modifications in signal integration

(2010) Yonathan Lissanu Deribe et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Identification of c-Src tyrosine kinase substrates in platelet-derived growth factor receptor signaling

(2009) Ramars Amanchy et al.   Molecular Oncology

Charting the molecular network of the drug target Bcr-Abl

(2009) M. Brehme et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteomic, functional and motif-based analysis of C-terminal Src kinase-interacting proteins

(2009) Guang Yang et al.   PROTEOMICS