A Tyrosine Phosphoproteome Analysis Approach Enabled by Selective Dephosphorylation with Protein Tyrosine Phosphatase

Rapid and site-specific deep phosphoproteome profiling by data-independent acquisition without the need for spectral libraries

(2020) Dorte B. Bekker-Jensen et al.   Nature Communications

One-Step SH2 Superbinder-Based Approach for Sensitive Analysis of Tyrosine Phosphoproteome

(2019) Yating Yao et al.   JOURNAL OF PROTEOME RESEARCH

The functional landscape of the human phosphoproteome

(2019) David Ochoa et al.   NATURE BIOTECHNOLOGY

Global Ion Suppression Limits the Potential of Mass Spectrometry Based Phosphoproteomics

(2018) Roland Felix Dreier et al.   JOURNAL OF PROTEOME RESEARCH

15 years of PhosphoSitePlus®: integrating post-translationally modified sites, disease variants and isoforms

(2018) Peter V Hornbeck et al.   NUCLEIC ACIDS RESEARCH

An immobilized titanium (IV) ion affinity chromatography adsorbent for solid phase extraction of phosphopeptides for phosphoproteome analysis

(2017) Yating Yao et al.   JOURNAL OF CHROMATOGRAPHY A

Mass-spectrometric exploration of proteome structure and function

(2016) Ruedi Aebersold et al.   NATURE

Ultra-deep tyrosine phosphoproteomics enabled by a phosphotyrosine superbinder

(2016) Yangyang Bian et al.   Nature Chemical Biology

The Perseus computational platform for comprehensive analysis of (prote)omics data

(2016) Stefka Tyanova et al.   NATURE METHODS

Evaluation of different phospho-tyrosine antibodies for label-free phosphoproteomics

(2015) Johannes C. van der Mijn et al.   Journal of Proteomics

High-throughput phosphoproteomics reveals in vivo insulin signaling dynamics

(2015) Sean J Humphrey et al.   NATURE BIOTECHNOLOGY

Kinase inhibitors and monoclonal antibodies in oncology: clinical implications

(2015) Helen Gharwan et al.   Nature Reviews Clinical Oncology

Accurate Proteome-wide Label-free Quantification by Delayed Normalization and Maximal Peptide Ratio Extraction, Termed MaxLFQ

(2014) Jürgen Cox et al.   MOLECULAR & CELLULAR PROTEOMICS

Mass-spectrometry-based draft of the human proteome

(2014) Mathias Wilhelm et al.   NATURE

Ultradeep Human Phosphoproteome Reveals a Distinct Regulatory Nature of Tyr and Ser/Thr-Based Signaling

(2014) Kirti Sharma et al.   Cell Reports

Protein Analysis by Shotgun/Bottom-up Proteomics

(2013) Yaoyang Zhang et al.   CHEMICAL REVIEWS

pLogo: a probabilistic approach to visualizing sequence motifs

(2013) Joseph P O'Shea et al.   NATURE METHODS

Robust phosphoproteome enrichment using monodisperse microsphere–based immobilized titanium (IV) ion affinity chromatography

(2013) Houjiang Zhou et al.   Nature Protocols

Modified SH2 domain to phototrap and identify phosphotyrosine proteins from subcellular sites within cells

(2012) A. Uezu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Superbinder SH2 Domains Act as Antagonists of Cell Signaling

(2012) T. Kaneko et al.   Science Signaling

Phosphotyrosine Signaling: Evolving a New Cellular Communication System

(2010) Wendell A. Lim et al.   CELL

Kinases as targets in the treatment of solid tumors

(2010) Georgios Giamas et al.   CELLULAR SIGNALLING

Preparation of monodisperse immobilized Ti4+ affinity chromatography microspheres for specific enrichment of phosphopeptides

(2009) Zhiyuan Yu et al.   ANALYTICA CHIMICA ACTA

Tyrosine phosphorylation: thirty years and counting

(2009) Tony Hunter   CURRENT OPINION IN CELL BIOLOGY

Phosphopeptide fragmentation and analysis by mass spectrometry

(2009) Paul J. Boersema et al.   JOURNAL OF MASS SPECTROMETRY

Peptide Sequence Scrambling Through Cyclization of b5 Ions

(2008) A HARRISON   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

Evolution of the phospho-tyrosine signaling machinery in premetazoan lineages

(2008) D. Pincus et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA