Role of SERCA and sarcolipin in adaptive muscle remodeling

The transmembrane peptide DWORF activates SERCA2a via dual mechanisms

(2021) Ang Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Is Upregulation of Sarcolipin Beneficial or Detrimental to Muscle Function?

(2021) Naresh C. Bal et al.   Frontiers in Physiology

Parvalbumin affects skeletal muscle trophism through modulation of mitochondrial calcium uptake

(2021) Gaia Butera et al.   Cell Reports

Mechanism of the lifespan extension induced by submaximal SERCA inhibition in C. elegans

(2021) Paloma García-Casas et al.   MECHANISMS OF AGEING AND DEVELOPMENT

LANCL1 binds abscisic acid and stimulates glucose transport and mitochondrial respiration in muscle cells via the AMPK/PGC-1α/Sirt1 pathway

(2021) Sonia Spinelli et al.   Molecular Metabolism

A hallmark of phospholamban functional divergence is located in the N-terminal phosphorylation domain

(2020) Eli Fernández-de Gortari et al.   Computational and Structural Biotechnology Journal

The Sarcoplasmic Reticulum and SERCA: a Nexus for Muscular Adaptive Thermogenesis

(2019) Daniel Gamu et al.   Applied Physiology Nutrition and Metabolism

Sarcolipin overexpression impairs myogenic differentiation in Duchenne muscular dystrophy

(2019) Nandita Niranjan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Cast immobilization of hindlimb upregulates sarcolipin expression in atrophied skeletal muscles and increases thermogenesis in C57BL/6J mice

(2019) Shigeto Tomiya et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Progerin in muscle leads to thermogenic and metabolic defects via impaired calcium homeostasis

(2019) Wan‐Ping Wang et al.   AGING CELL

AMPK in skeletal muscle function and metabolism

(2018) Rasmus Kjøbsted et al.   FASEB JOURNAL

Skeletal muscle-specific Sidt2 knockout in mice induced muscular dystrophy-like phenotype

(2018) Huan Liu et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Inhibition of Sarco-Endoplasmic Reticulum Ca2+ ATPase Extends the Lifespan in C. elegans Worms

(2018) Paloma García-Casas et al.   Frontiers in Pharmacology

Truncated dystrophin ameliorates the dystrophic phenotype of mdx mice by reducing sarcolipin-mediated SERCA inhibition

(2018) Jun Tanihata et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Sarcolipin deletion in mdx mice impairs calcineurin signalling and worsens dystrophic pathology

(2018) Val A Fajardo et al.   HUMAN MOLECULAR GENETICS

Sarcolipin Signaling Promotes Mitochondrial Biogenesis and Oxidative Metabolism in Skeletal Muscle

(2018) Santosh K. Maurya et al.   Cell Reports

Regulator of Calcineurin 1 helps coordinate whole‐body metabolism and thermogenesis

(2018) David Rotter et al.   EMBO REPORTS

Misregulation of calcium-handling proteins promotes hyperactivation of calcineurin–NFAT signaling in skeletal muscle of DM1 mice

(2017) Aymeric Ravel-Chapuis et al.   HUMAN MOLECULAR GENETICS

Sarcolipin expression is not required for the mitochondrial enzymatic response to physical activity or diet

(2017) Daniel Gamu et al.   JOURNAL OF APPLIED PHYSIOLOGY

Interactions between small ankyrin 1 and sarcolipin coordinately regulate activity of the sarco(endo)plasmic reticulum Ca 2+ -ATPase (SERCA1)

(2017) Patrick F. Desmond et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reducing sarcolipin expression mitigates Duchenne muscular dystrophy and associated cardiomyopathy in mice

(2017) Antanina Voit et al.   Nature Communications

Sarcolipin deletion exacerbates soleus muscle atrophy and weakness in phospholamban overexpressing mice

(2017) Val A. Fajardo et al.   PLoS One

Calcium signaling in skeletal muscle development, maintenance and regeneration

(2016) Michelle K. Tu et al.   CELL CALCIUM

A peptide encoded by a transcript annotated as long noncoding RNA enhances SERCA activity in muscle

(2016) B. R. Nelson et al.   SCIENCE

Widespread control of calcium signaling by a family of SERCA-inhibiting micropeptides

(2016) D. M. Anderson et al.   Science Signaling

Widespread control of calcium signaling by a family of SERCA-inhibiting micropeptides

(2016) D. M. Anderson et al.   Science Signaling

Diaphragm assessment in mice overexpressing phospholamban in slow-twitch type I muscle fibers

(2016) Val Andrew Fajardo et al.   Brain and Behavior

SERCA1 overexpression minimizes skeletal muscle damage in dystrophic mouse models

(2015) Davi A. G. Mázala et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The effects of sarcolipin over-expression in mouse skeletal muscle on metabolic activity

(2015) John Butler et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

A Micropeptide Encoded by a Putative Long Noncoding RNA Regulates Muscle Performance

(2015) Douglas M. Anderson et al.   CELL

Phospholamban overexpression in mice causes a centronuclear myopathy-like phenotype

(2015) V. A. Fajardo et al.   Disease Models & Mechanisms

Sarcolipin overexpression improves muscle energetics and reduces fatigue

(2015) Danesh H. Sopariwala et al.   JOURNAL OF APPLIED PHYSIOLOGY

Sarcolipin Is a Key Determinant of the Basal Metabolic Rate, and Its Overexpression Enhances Energy Expenditure and Resistance against Diet-induced Obesity

(2015) Santosh K. Maurya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The N Terminus of Sarcolipin Plays an Important Role in Uncoupling Sarco-endoplasmic Reticulum Ca2+-ATPase (SERCA) ATP Hydrolysis from Ca2+Transport

(2015) Sanjaya K. Sahoo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of Small Ankyrin 1 as a Novel Sarco(endo)plasmic Reticulum Ca2+-ATPase 1 (SERCA1) Regulatory Protein in Skeletal Muscle

(2015) Patrick F. Desmond et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cold adaptation overrides developmental regulation of sarcolipin expression in mice skeletal muscle: SOS for muscle-based thermogenesis?

(2015) M. Pant et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Sarcolipin is a novel regulator of muscle metabolism and obesity

(2015) Santosh Kumar Maurya et al.   PHARMACOLOGICAL RESEARCH

The Effect of SERCA1b Silencing on the Differentiation and Calcium Homeostasis of C2C12 Skeletal Muscle Cells

(2015) Adrienn Tóth et al.   PLoS One

Metabolic Dysfunction and Altered Mitochondrial Dynamics in the Utrophin-Dystrophin Deficient Mouse Model of Duchenne Muscular Dystrophy

(2015) Meghna Pant et al.   PLoS One

Ablation of sarcolipin decreases the energy requirements for Ca2+transport by sarco(endo)plasmic reticulum Ca2+-ATPases in resting skeletal muscle

(2013) Eric Bombardier et al.   FEBS LETTERS

Increased sarcolipin expression and decreased sarco(endo)plasmic reticulum Ca2+ uptake in skeletal muscles of mouse models of Duchenne muscular dystrophy

(2013) Joel S. Schneider et al.   JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY

ATP Consumption by Sarcoplasmic Reticulum Ca2+ Pumps Accounts for 40-50% of Resting Metabolic Rate in Mouse Fast and Slow Twitch Skeletal Muscle

(2013) Ian Curtis Smith et al.   PLoS One

Co-Expression of SERCA Isoforms, Phospholamban and Sarcolipin in Human Skeletal Muscle Fibers

(2013) Val A. Fajardo et al.   PLoS One

Dynamic regulation of sarcoplasmic reticulum Ca2+ stores by stromal interaction molecule 1 and sarcolipin during muscle differentiation

(2012) Malini Seth et al.   DEVELOPMENTAL DYNAMICS

Regulation of MEF2 transcriptional activity by calcineurin/mAKAP complexes

(2012) Jinliang Li et al.   EXPERIMENTAL CELL RESEARCH

Increased Resting Intracellular Calcium Modulates NF-κB-dependent Inducible Nitric-oxide Synthase Gene Expression in DystrophicmdxSkeletal Myotubes

(2012) Francisco Altamirano et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterizing Phospholamban to Sarco(endo)plasmic Reticulum Ca2+-ATPase 2a (SERCA2a) Protein Binding Interactions in Human Cardiac Sarcoplasmic Reticulum Vesicles Using Chemical Cross-linking

(2012) Brandy L. Akin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hsp72 preserves muscle function and slows progression of severe muscular dystrophy

(2012) Stefan M. Gehrig et al.   NATURE

Sarcolipin is a newly identified regulator of muscle-based thermogenesis in mammals

(2012) Naresh C Bal et al.   NATURE MEDICINE

Genetic Biomarkers for ALS Disease in Transgenic SOD1G93A Mice

(2012) Ana C. Calvo et al.   PLoS One

Rapid Determination of Myosin Heavy Chain Expression in Rat, Mouse, and Human Skeletal Muscle Using Multicolor Immunofluorescence Analysis

(2012) Darin Bloemberg et al.   PLoS One

Enhanced Ca2+ transport and muscle relaxation in skeletal muscle from sarcolipin-null mice

(2011) A. Russell Tupling et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

A Muscle-Specific p38 MAPK/Mef2/MnSOD Pathway Regulates Stress, Motor Function, and Life Span in Drosophila

(2011) Alysia Vrailas-Mortimer et al.   DEVELOPMENTAL CELL

Mice lacking microRNA 133a develop dynamin 2–dependent centronuclear myopathy

(2011) Ning Liu et al.   JOURNAL OF CLINICAL INVESTIGATION

Mitigation of muscular dystrophy in mice by SERCA overexpression in skeletal muscle

(2011) Sanjeewa A. Goonasekera et al.   JOURNAL OF CLINICAL INVESTIGATION

Changes in mitochondrial reactive oxygen species synthesis during differentiation of skeletal muscle cells

(2011) Dominika Malinska et al.   MITOCHONDRION

Protective effects of Hsp70 on the structure and function of SERCA2a expressed in HEK-293 cells during heat stress

(2009) M. H. Fu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Transcriptional and post-transcriptional impact of toxic RNA in myotonic dystrophy

(2009) Robert J. Osborne et al.   HUMAN MOLECULAR GENETICS

Cyclosporin A modulates cellular localization of MEF2C protein and blocks fiber hypertrophy in the overloaded soleus muscle of mice

(2008) Kunihiro Sakuma et al.   ACTA NEUROPATHOLOGICA

Sarcoplasmic reticulum calcium uptake and speed of relaxation are depressed in nebulin-free skeletal muscle

(2008) Coen A. C. Ottenheijm et al.   FASEB JOURNAL

Genetic and pharmacologic inhibition of mitochondrial-dependent necrosis attenuates muscular dystrophy

(2008) Douglas P Millay et al.   NATURE MEDICINE

Cellular adaptations in soleus muscle during recovery after hindlimb unloading

(2007) Y. Oishi et al.   Acta Physiologica