Hierarchical Therapeutic Ion‐Based Microspheres with Precise Ratio‐Controlled Delivery as Microscaffolds for In Situ Vascularized Bone Regeneration

Biological Roles and Delivery Strategies for Ions to Promote Osteogenic Induction

(2021) Elia Bosch-Rué et al.   Frontiers in Cell and Developmental Biology

Electroactive electrospun nanofibers for tissue engineering

(2021) Xiaodi Zhang et al.   Nano Today

Hypoxia-mimicking 3D bioglass-nanoclay scaffolds promote endogenous bone regeneration

(2021) Xiao Zheng et al.   Bioactive Materials

Inorganic Biomaterials for Regenerative Medicine

(2020) Anna M. Brokesh et al.   ACS Applied Materials & Interfaces

A novel photothermally controlled multifunctional scaffold for clinical treatment of osteosarcoma and tissue regeneration

(2020) Liang Ma et al.   Materials Today

Mineralization of ytterbium-doped hydroxyapatite nanorod arrays in magnetic chitosan scaffolds improves osteogenic and angiogenic abilities for bone defect healing

(2020) Ya-Qi Tang et al.   CHEMICAL ENGINEERING JOURNAL

Bisphosphonate nanoclay edge-site interactions facilitate hydrogel self-assembly and sustained growth factor localization

(2020) Yang-Hee Kim et al.   Nature Communications

Dual‐Controlled Release of Icariin/Mg 2+ from Biodegradable Microspheres and Their Synergistic Upregulation Effect on Bone Regeneration

(2020) Zuoying Yuan et al.   Advanced Healthcare Materials

Exosome-mimetics as an engineered gene-activated matrix induces in-situ vascularized osteogenesis

(2020) Yao Zha et al.   BIOMATERIALS

Engineered biomaterials for in situ tissue regeneration

(2020) Akhilesh K. Gaharwar et al.   Nature Reviews Materials

Multifunctional bioactive Nd-Ca-Si glasses for fluorescence thermometry, photothermal therapy, and burn tissue repair

(2020) Lingling Ma et al.   Science Advances

Highly tunable bioactive fiber-reinforced hydrogel for guided bone regeneration

(2020) Nileshkumar Dubey et al.   Acta Biomaterialia

Combinatorial Fluorapatite bioceramic substituted with strontium, magnesium and silicon ions for mending bone defects

(2020) Nasim Golafshan et al.   Materials Science & Engineering C-Materials for Biological Applications

3D bioprinting spatiotemporally defined patterns of growth factors to tightly control tissue regeneration

(2020) Fiona E. Freeman et al.   Science Advances

Complementary and synergistic effects on osteogenic and angiogenic properties of copper-incorporated silicocarnotite bioceramic: In vitro and in vivo studies

(2020) Qiang Wu et al.   BIOMATERIALS

Early healing of alveolar bone promoted by microRNA-21-loaded nanoparticles combined with Bio-Oss particles

(2020) Xueping Li et al.   CHEMICAL ENGINEERING JOURNAL

Nanoclay promotes mouse cranial bone regeneration mainly through modulating drug binding and sustained release

(2020) Jue Hu et al.   Applied Materials Today

Osteogenesis, angiogenesis and immune response of Mg-Al layered double hydroxide coating on pure Mg

(2020) Shi Cheng et al.   Bioactive Materials

Cryogenic 3D printing of dual-delivery scaffolds for improved bone regeneration with enhanced vascularization

(2020) Chong Wang et al.   Bioactive Materials

Lanthanum-doped mesoporous bioglasses/chitosan composite scaffolds enhance synchronous osteogenesis and angiogenesis for augmented osseous regeneration

(2020) Daoyu Zhu et al.   CHEMICAL ENGINEERING JOURNAL

Stepwise 3D-spatio-temporal magnesium cationic niche: Nanocomposite scaffold mediated microenvironment for modulating intramembranous ossification

(2020) Jie Shen et al.   Bioactive Materials

CO2 solubility in brine in silica nanopores in relation to geological CO2 sequestration in tight formations: Effect of salinity and pH

(2020) Wenhui Li et al.   CHEMICAL ENGINEERING JOURNAL

Synergistic anti-inflammatory and osteogenic n-HA/resveratrol/chitosan composite microspheres for osteoporotic bone regeneration

(2020) Limei Li et al.   Bioactive Materials

Simultaneous incorporation of PTH(1–34) and nano-hydroxyapatite into Chitosan/Alginate Hydrogels for efficient bone regeneration

(2020) Zhiyuan Zou et al.   Bioactive Materials

Combinatorial effects of inorganic ions on adhesion and proliferation of osteoblast‐like cells

(2019) Akiko Obata et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Roles of electrical stimulation in promoting osteogenic differentiation of BMSCs on conductive fibers

(2019) Wei Jing et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Osteogenic magnesium incorporated into PLGA/TCP porous scaffold by 3D printing for repairing challenging bone defect

(2019) Yuxiao Lai et al.   BIOMATERIALS

Regulating substrate mechanics to achieve odontogenic differentiation for dental pulp stem cells on TiO2 filled and unfilled polyisoprene

(2019) Ya-Chen Chuang et al.   Acta Biomaterialia

2D Nanoclay for Biomedical Applications: Regenerative Medicine, Therapeutic Delivery, and Additive Manufacturing

(2019) Akhilesh K. Gaharwar et al.   ADVANCED MATERIALS

A Magnesium‐Enriched 3D Culture System that Mimics the Bone Development Microenvironment for Vascularized Bone Regeneration

(2019) Sihan Lin et al.   Advanced Science

3D Superelastic Scaffolds Constructed from Flexible Inorganic Nanofibers with Self‐Fitting Capability and Tailorable Gradient for Bone Regeneration

(2019) Lihuan Wang et al.   ADVANCED FUNCTIONAL MATERIALS

Vancomycin- and Strontium-Loaded Microspheres with Multifunctional Activities against Bacteria, in Angiogenesis, and in Osteogenesis for Enhancing Infected Bone Regeneration

(2019) Pengfei Wei et al.   ACS Applied Materials & Interfaces

A 3D Printable and Bioactive Hydrogel Scaffold to Treat Traumatic Brain Injury

(2019) Lingbin Che et al.   ADVANCED FUNCTIONAL MATERIALS

Biomimetic Nanosilica–Collagen Scaffolds for In Situ Bone Regeneration: Toward a Cell‐Free, One‐Step Surgery

(2019) Shao‐Jie Wang et al.   ADVANCED MATERIALS

Current advances in microsphere based cell culture and tissue engineering

(2019) Qiulin He et al.   BIOTECHNOLOGY ADVANCES

Dual Function of Magnesium in Bone Biomineralization

(2019) Jinglun Zhang et al.   Advanced Healthcare Materials

Cu-doping of calcium phosphate bioceramics: From mechanism to the control of cytotoxicity

(2018) Sandrine Gomes et al.   Acta Biomaterialia

Injectable nanocomposite cryogels for versatile protein drug delivery

(2018) Sandeep T. Koshy et al.   Acta Biomaterialia

RNA interfering molecule delivery from in situ forming biodegradable hydrogels for enhancement of bone formation in rat calvarial bone defects

(2018) Minh K. Nguyen et al.   Acta Biomaterialia

Understanding interactions between biomaterials and biological systems using proteomics

(2018) Ziryan Othman et al.   BIOMATERIALS

Precisely controlled delivery of magnesium ions thru sponge-like monodisperse PLGA/nano-MgO-alginate core-shell microsphere device to enable in-situ bone regeneration

(2018) Zhengjie Lin et al.   BIOMATERIALS

The roles of ions on bone regeneration

(2018) Edward O’Neill et al.   DRUG DISCOVERY TODAY

Bone physiology as inspiration for tissue regenerative therapies

(2018) Diana Lopes et al.   BIOMATERIALS

Micro/Nanometer-Structured Scaffolds for Regeneration of Both Cartilage and Subchondral Bone

(2018) Cuijun Deng et al.   ADVANCED FUNCTIONAL MATERIALS

Injectable PLGA microspheres with tunable magnesium ion release for promoting bone regeneration

(2018) Zuoying Yuan et al.   Acta Biomaterialia

3D robocasting magnesium-doped wollastonite/TCP bioceramic scaffolds with improved bone regeneration capacity in critical sized calvarial defects

(2017) Huifeng Shao et al.   Journal of Materials Chemistry B

Concentration-dependent behaviors of bone marrow derived mesenchymal stem cells and infectious bacteria toward magnesium oxide nanoparticles

(2016) Cheyann Lee Wetteland et al.   Acta Biomaterialia

Biomaterials Act as Enhancers of Growth Factors in Bone Regeneration

(2016) Rui Chen et al.   ADVANCED FUNCTIONAL MATERIALS

Sequential and sustained release of SDF-1 and BMP-2 from silk fibroin-nanohydroxyapatite scaffold for the enhancement of bone regeneration

(2016) Xiaofeng Shen et al.   BIOMATERIALS

Bone induction at physiological doses of BMP through localization by clay nanoparticle gels

(2016) D.M.R. Gibbs et al.   BIOMATERIALS

High-purity magnesium interference screws promote fibrocartilaginous entheses regeneration in the anterior cruciate ligament reconstruction rabbit model via accumulation of BMP-2 and VEGF

(2016) Pengfei Cheng et al.   BIOMATERIALS

Polycaprolactone-laponite composite scaffold releasing strontium ranelate for bone tissue engineering applications

(2016) Bindu P. Nair et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Osteoimmunomodulation for the development of advanced bone biomaterials

(2016) Zetao Chen et al.   Materials Today

Implant-derived magnesium induces local neuronal production of CGRP to improve bone-fracture healing in rats

(2016) Yifeng Zhang et al.   NATURE MEDICINE

Differentiation of Dental Pulp Stem Cells on Gutta-Percha Scaffolds

(2016) Liudi Zhang et al.   Polymers

Investigation of magnesium–zinc–calcium alloys and bone marrow derived mesenchymal stem cell response in direct culture

(2015) Aaron F. Cipriano et al.   Acta Biomaterialia

Extracellular matrix-inspired growth factor delivery systems for bone regeneration

(2015) Mikaël M. Martino et al.   ADVANCED DRUG DELIVERY REVIEWS

Targeted delivery as key for the success of small osteoinductive molecules

(2015) Elizabeth R. Balmayor   ADVANCED DRUG DELIVERY REVIEWS

Role of Magnesium Transporter Subtype 1 (MagT1) in the Osteogenic Differentiation of Rat Bone Marrow Stem Cells

(2015) Jianmao Zheng et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Magnesium in Man: Implications for Health and Disease

(2015) Jeroen H. F. de Baaij et al.   PHYSIOLOGICAL REVIEWS

Magnesium ion stimulation of bone marrow stromal cells enhances osteogenic activity, simulating the effect of magnesium alloy degradation

(2014) Sayuri Yoshizawa et al.   Acta Biomaterialia

Stimulatory effects of the ionic products from Ca–Mg–Si bioceramics on both osteogenesis and angiogenesis in vitro

(2013) Wanyin Zhai et al.   Acta Biomaterialia

pH-sensitive Laponite®/doxorubicin/alginate nanohybrids with improved anticancer efficacy

(2013) Mara Gonçalves et al.   Acta Biomaterialia

Bioactive Silicate Nanoplatelets for Osteogenic Differentiation of Human Mesenchymal Stem Cells

(2013) Akhilesh K. Gaharwar et al.   ADVANCED MATERIALS

Small molecules and small molecule drugs in regenerative medicine

(2013) Baisong Lu et al.   DRUG DISCOVERY TODAY

Evaluation of bone regeneration using the rat critical size calvarial defect

(2012) Patrick P Spicer et al.   Nature Protocols

A review of the biological response to ionic dissolution products from bioactive glasses and glass-ceramics

(2011) Alexander Hoppe et al.   BIOMATERIALS