Article
Psychiatry
Xiao Li, Xiaolu Chen, Renqiang Yu, Linqi Dai, Ming Ai, Qian Huang, Yi Zhou, Wanjun Chen, Jiamei Guo, Anhai Zheng, Li Kuang
Summary: Changes in frontal-temporal-precuneus structures may be associated with depressive and suicidal symptoms in adolescents. Electroconvulsive therapy (ECT) may improve depressive and suicidal symptoms in adolescents by regulating brain structures.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Behavioral Sciences
Xiaolu Chen, Yixiao Fu, Qianhong Zou, Yiting Zhang, Xiaoyue Qin, Yu Tian, Yu Yan, Qibin Chen, Lei Zou, Bangshu Zhao, Xiao Li
Summary: This study analyzed the use and outcome of electroconvulsive therapy (ECT) in adolescents with depression and suicidal symptoms. It found that ECT was effective in reducing depressive and suicidal symptoms in adolescents, with acceptable side effects. ECT showed better outcome for major depressive disorder (MDD) with suicide attempt compared to MDD with suicidal ideation.
BRAIN AND BEHAVIOR
(2022)
Article
Behavioral Sciences
Haipeng Cai, Ruonan Du, Jiaqi Song, Zhiren Wang, Xin Wang, Yongjun Yu, Yanan Wang, Lan Shang, Jianxin Zhang, Kebing Yang, Wei Li
Summary: This study investigated the efficacy and safety of electroconvulsive therapy (ECT) in improving suicidal ideation and depressive symptoms in adolescents with major depressive disorder. The findings showed that ECT treatment significantly improved suicidal ideation and depressive symptoms. Although there were transient impairments in some cognitive functions, they gradually recovered after ECT.
Article
Psychiatry
James Luccarelli, Daniel Humphrey, Thomas H. Mccoy Jr, Michael E. Henry, Martina Mueller, Stephen J. Seiner
Summary: This study aimed to quantify changes in self-reported suicidal ideation (SI) during electroconvulsive therapy (ECT) treatment and identify factors associated with persistent SI in patients starting treatment with SI. The results showed that ECT treatment was associated with reductions in self-reported SI. These findings support the use of ECT in patients with SI, but further research is needed to determine the effects of ECT on suicidal behavior.
ACTA PSYCHIATRICA SCANDINAVICA
(2023)
Article
Clinical Neurology
Kannapas Kittayarak, Pichai Ittasakul
Summary: The practice of electroconvulsive therapy (ECT) in Thailand has seen significant development over the past two decades, with the majority of patients now being treated with modified ECT. The use of pre-treatment investigations, devices providing brief pulses, unilateral electrode placement, and monitoring of treatment parameters has also become more widespread to enhance treatment efficacy and minimize side effects. However, there are still areas for improvement, such as promoting ECT education among psychiatrists and psychiatry residents.
NEUROPSYCHIATRIC DISEASE AND TREATMENT
(2022)
Article
Neurosciences
Xiao Li, Xiaolu Chen, Yi Zhou, Linqi Dai, Long-Biao Cui, Renqiang Yu, Ming Ai, Qian Huang, Yu Tian, Mei Ming, Li Kuang
Summary: This study used rs-fMRI to reveal the changes in brain function in adolescents with depression and suicidal ideation after electroconvulsive therapy (ECT). By examining the alterations in amplitude of low-frequency fluctuations (ALFF) and regional homogeneity (ReHo), it was found that the abnormal activities of the amygdala, inferior temporal gyrus, and middle occipital gyrus are associated with depressive and suicidal symptoms.
Review
Biology
Kevin Lee, Kimberly D. Jenkins, Tanaya Sparkle
Summary: Electroconvulsive therapy (ECT) is an effective treatment for severe psychiatric disorders, and providing appropriate anesthesia for ECT is challenging, requiring consideration of the patient's condition and associated risks.
Article
Clinical Neurology
Hong Li, Lingzhi Hou, Dong Wang, Qijin Wu, Haijin Li, Wen He, Sheng Li, Jianyue Pang, Yanyan Zhang, Quangang Ma, Cai Li, Jun Cheng
Summary: This study found that the combination of antidepressants and electroconvulsive therapy (ECT) is highly effective and safe for treating depression in both adolescents and adults. Depressed adolescents expressed stronger suicidal intent, which was alleviated by ECT. There were no significant differences in depression symptoms and treatment outcomes between adolescents and adults, and the side effects were similar.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Clinical Neurology
Nujaree Sombatcharoen-non, Thidarat Yamnim, Sudawan Jullagate, Pichai Ittasakul
Summary: This retrospective mirror-image study found that continuation-maintenance electroconvulsive therapy (ECT) can effectively reduce psychiatric hospitalizations and admission days in Thai patients with various psychiatric diagnoses.
NEUROPSYCHIATRIC DISEASE AND TREATMENT
(2023)
Article
Clinical Neurology
Santiago Madero, Gerard Anmella, Maria Sague-Vilavella, Maria Teresa Pons, Anna Gimenez, Andrea Murru, Marta Gomez-Ramiro, Joaquin Gil-Badenes, Jose Rios, Miquel Bioque, Eduard Vieta, Antonio Benabarre
Summary: This study aimed to investigate the real-life effectiveness of maintenance electroconvulsive therapy(mECT) in bipolar disorder(BD). The results showed that mECT can effectively reduce the number and duration of psychiatric hospitalizations in BD patients, supporting its effectiveness in the treatment of BD.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Clinical Neurology
Santiago Madero, Gerard Anmella, Maria Sague-Vilavella, Maria Teresa Pons, Anna Gimenez, Andrea Murru, Marta Gomez-Ramiro, Joaquin Gil-Badenes, Jose Rios, Miquel Bioque, Eduard Vieta, Antonio Benabarre
Summary: This study aimed to investigate the effectiveness of maintenance electroconvulsive therapy (mECT) in treating bipolar disorder (BD). The results showed that mECT had a 62.2% effectiveness in preventing psychiatric hospitalizations and significantly reduced the number of hospitalization days and admissions for BD patients.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Review
Medicine, General & Internal
Randall T. Espinoza, Charles H. Kellner
Summary: Update on Electroconvulsive Therapy (ECT): ECT is effective for several disorders, notably severe or treatment-resistant depression, showing rapid response. However, stigma hampers its usage. The mechanism remains unknown, but a seizure is necessary for efficacy. ECT prominently affects memory, albeit transiently.
NEW ENGLAND JOURNAL OF MEDICINE
(2022)
Article
Psychiatry
Isabel Methfessel, Matthias Besse, Michael Belz, David Zilles-Wegner
Summary: This study found that reducing or discontinuing c-/m-ECT treatment can lead to significant clinical deterioration, including rehospitalizations and new courses of ECT. During the COVID-19 pandemic, modifications to treatment plans had a significant impact on the clinical outcomes of patients.
ACTA PSYCHIATRICA SCANDINAVICA
(2021)
Article
Medicine, General & Internal
Virginie Moulier, Julien Guehl, Emilie Eveque-Mourroux, Pierre Quesada, Maud Rotharmel
Summary: The objective of this study was to determine the relationship between clinical response and postictal suppression indicators during ECT treatment. The results showed that postictal suppression from the first ECT session can predict long-term clinical response, but not early clinical response. Postictal suppression frequency was not associated with clinical response, and there was also no association between postictal suppression and short-term cognitive performance.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Clinical Neurology
V. Millischer, S. Pramhas, I. Wiedermann, V. Eder, H. G. Kress, A. Michalek-Sauberer, D. Rujescu, R. Frey, P. Baldinger-Melich
Summary: This retrospective study compared the effects of etomidate and methohexital as anesthetic agents in ECT treatment. The results showed that etomidate was inferior to methohexital, as it led to longer procedure duration and poor side effects.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Geriatrics & Gerontology
Simon Lambrichts, Margot J. Wagenmakers, Kristof Vansteelandt, Jasmien Obbels, Sigfried N. T. M. Schouws, Esmee Verwijk, Eric van Exel, Filip Bouckaert, Mathieu Vandenbulcke, Didier Schrijvers, Dick J. Veltman, Aartjan T. F. Beekman, Mardien L. Oudega, Pascal Sienaert, Annemiek Dols
Summary: This study examined the five-year outcomes of patients with severe late-life depression who underwent electroconvulsive therapy (ECT). The study found that relapse rates, cognitive impairment, and mortality were consistent with long-term outcomes following other acute treatments for severe late-life depression.
AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY
(2022)
Review
Behavioral Sciences
Sophie Hartnett, Steffen Rex, Pascal Sienaert
Summary: This article reviews the effect of electrode placement on the incidence and severity of bradycardia and asystole during electroconvulsive therapy (ECT). The evidence suggests that right unilateral placement carries a higher risk for developing bradycardia and asystole than bitemporal and bifrontal placement.
Article
Behavioral Sciences
Jelle Vandeurzen, Kristof Vansteelandt, Sophie Lemmens, Pascal Sienaert
Summary: The aim of this study was to evaluate changes in intraocular pressure (IOP) during and after electroconvulsive therapy (ECT). The results showed that in the right unilateral electrode placement group, there was a significant increase in IOP during the seizure and a return to normal after the seizure, with differences in IOP between the left and right eye. In conclusion, right unilateral ECT causes an increase in IOP, which is partially lateralized and higher on the right side.
Article
Psychiatry
Mia Ramklint, Per Soderberg, Stefan Tungstrom, Axel Nordenskjold, Liselotte Hermansson
Summary: The study aimed to investigate the concurrent validity of the Swedish self-rated 36-item World Health Organization Disability Assessment Schedule (WHODAS) 2.0 by comparing it with professional Global Assessment of Functioning (GAF) ratings in psychiatric outpatients. The results showed a significant correlation between WHODAS 2.0 scores and GAF ratings, indicating good concurrent validity. The WHODAS 2.0 demonstrated good ability to assess impaired functioning.
NORDIC JOURNAL OF PSYCHIATRY
(2023)
Editorial Material
Clinical Neurology
Hanna Tu, Eva Pilato, Pascal Sienaert
Article
Clinical Neurology
M. A. J. T. Blanken, M. L. Oudega, A. W. Hoogendoorn, C. S. Sonnenberg, D. Rhebergen, U. M. H. Klumpers, L. Van Diermen, T. Birkenhager, D. Schrijvers, R. Redlich, U. Dannlowski, W. Heindel, M. Coenjaerts, P. Nordanskog, L. Oltedal, U. Kessler, L. M. Frid, A. Takamiya, T. Kishimoto, M. B. Jorgensen, A. Jorgensen, T. Bolwig, L. Emsell, P. Sienaert, F. Bouckaert, C. C. Abbott, P. Peran, C. Arbus, A. Yrondi, M. Kiebs, A. Philipsen, J. A. van Waarde, E. Prinsen, M. van Verseveld, G. Van Wingen, F. ten Doesschate, J. A. Camprodon, M. Kritzer, T. Barbour, M. Argyelan, N. Cardoner, M. Urretavizcaya, C. Soriano-Mas, K. L. Narr, R. T. Espinoza, J. Prudic, S. Rowny, Ph. van Eijndhoven, I. Tendolkar, A. Dols
Summary: Electroconvulsive therapy (ECT) is equally effective for both men and women with severe major depressive disorder (MDD). However, shorter duration of index episode may serve as a specific predictor for remission in women.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Editorial Material
Psychiatry
Pascal Sienaert, Declan M. McLoughlin
ACTA PSYCHIATRICA SCANDINAVICA
(2023)
Article
Psychiatry
Adam Nygren, Johan Reutfors, Lena Brandt, Robert Boden, Axel Nordenskjoeld, Mikael Tiger
Summary: This study investigated the response rates after electroconvulsive therapy (ECT) in patients with non-psychotic treatment-resistant depression (TRD) and found that the response rate was slightly lower in patients with non-TRD compared to TRD.
Article
Education & Educational Research
Emma De Schuyteneer, Bram Dewachter, Kristof Vansteelandt, Eva Pilato, Bo Crauwels, Simon Lambrichts, Shauni Verspecht, Kaat Hebbrecht, Jasmien Obbels, Pascal Sienaert
Summary: This study aims to evaluate medical students' knowledge about and attitudes towards electroconvulsive therapy (ECT) and to determine the impact of different information sources on their knowledge and attitudes. The results show that final-year students have better knowledge about and more positive attitudes towards ECT compared to first-year students, partially due to differences in information sources. However, both groups of students have limited knowledge about ECT, potentially because of inadequate instruction in medical courses. The use of media as an information source predicts negative attitudes towards ECT.
ACADEMIC PSYCHIATRY
(2023)
Article
Psychiatry
Tor Arnison, Olof Rask, Axel Nordenskjold, Pouya Movahed Rad
Summary: Psychiatric disorders during pregnancy can have negative effects on both the mother and fetus, and electroconvulsive therapy (ECT) may be an effective treatment option. A study found that the response rate to ECT in pregnant women was similar to non-pregnant women, but there was a higher risk of premature birth and poorer condition in newborns.
ACTA PSYCHIATRICA SCANDINAVICA
(2023)
Article
Psychiatry
Ahmed Al-Wandi, Mikael Landen, Axel Nordenskjoeld
Summary: The study compared the outcomes of patients with psychotic unipolar depression treated with antidepressants alone versus in combination with antipsychotics. The results showed that monotherapy was associated with a lower risk of hospital readmission and suicide compared to combination therapy. Additional research is needed to determine the effectiveness of antipsychotics in the maintenance phase of psychotic unipolar depression.
ACTA PSYCHIATRICA SCANDINAVICA
(2023)
Article
Geriatrics & Gerontology
Thomas C. Feenstra, Eldon K. J. la Cruz, Jasmien Obbels, Maarten Laroy, Filip Bouckaert, Pascal Sienaert, Mardien Oudega, Annemieke Dols, Eric van Exel, Aartjan T. F. Beekman, Didi Rhebergen
Summary: This study investigated the potential use of the cortisol awakening response (CAR) as a biomarker for cognitive decline during electroconvulsive therapy (ECT). The findings suggest that CAR is not a reliable biomarker for ECT-induced cognitive decline during the therapy course.
AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY
(2023)
Review
Behavioral Sciences
Alain P. P. Nicolini, Pascal Sienaert
Summary: This systematic review evaluates whether the presence of borderline personality disorder (BPD) reduces the response to electroconvulsive therapy (ECT) in individuals with major depressive disorder (MDD). The study found that patients with comorbid BPD had a less robust response to ECT, but ECT remained an effective treatment option for this patient group.
Article
Psychiatry
Olivia Ernstsson, Emelie Heintz, Axel Nordenskjold, Jeffrey A. Johnson, Seher Korkmaz, Niklas Zethraeus
Summary: There is no significant association between pulse width and HRQoL after electroconvulsive therapy (ECT). Patients with unipolar or bipolar depression showed significant improvements in HRQoL one week and six months after ECT, regardless of the pulse width received.
NORDIC JOURNAL OF PSYCHIATRY
(2023)