Development of a Localized Drug Delivery System with a Step-by-Step Cell Internalization Capacity for Cancer Immunotherapy

Photothermal hydrogel platform for prevention of post-surgical tumor recurrence and improving breast reconstruction

(2021) Xi Yang et al.   JOURNAL OF NANOBIOTECHNOLOGY

A review of cancer immunotherapy toxicity

(2020) Lucy Boyce Kennedy et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Modularly Designed Peptide Nanoprodrug Augments Antitumor Immunity of PD-L1 Checkpoint Blockade by Targeting Indoleamine 2,3-Dioxygenase

(2020) Xuexiang Han et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Improving cancer immunotherapy using nanomedicines: progress, opportunities and challenges

(2020) John D. Martin et al.   Nature Reviews Clinical Oncology

Mannose receptor (CD206) activation in tumor-associated macrophages enhances adaptive and innate antitumor immune responses

(2020) Jesse M. Jaynes et al.   Science Translational Medicine

Nanoparticle interactions with immune cells dominate tumor retention and induce T cell–mediated tumor suppression in models of breast cancer

(2020) Preethi Korangath et al.   Science Advances

Development of a pH-responsive polymersome inducing endoplasmic reticulum stress and autophagy blockade

(2020) Funeng Xu et al.   Science Advances

Neutrophils preferentially phagocytose elongated particles—An opportunity for selective targeting in acute inflammatory diseases

(2020) Hanieh Safari et al.   Science Advances

A Hierarchical Structured Ultrafine Fiber Device for Preventing Postoperative Recurrence and Metastasis of Breast Cancer

(2020) Xilin Li et al.   ADVANCED FUNCTIONAL MATERIALS

Delivery technologies for cancer immunotherapy

(2019) Rachel S. Riley et al.   NATURE REVIEWS DRUG DISCOVERY

Programmable Codelivery of Doxorubicin and Apatinib Using an Implantable Hierarchical-Structured Fiber Device for Overcoming Cancer Multidrug Resistance

(2019) Yang He et al.   Small

Cancer nanomedicine for combination cancer immunotherapy

(2019) Jutaek Nam et al.   Nature Reviews Materials

CD24 signalling through macrophage Siglec-10 is a target for cancer immunotherapy

(2019) Amira A. Barkal et al.   NATURE

Chondroitin Sulfate-Linked Prodrug Nanoparticles Target the Golgi Apparatus for Cancer Metastasis Treatment

(2019) Haohuan Li et al.   ACS Nano

Smart Injectable Hydrogels for Cancer Immunotherapy

(2019) Yu Chao et al.   ADVANCED FUNCTIONAL MATERIALS

Progress on Modulating Tumor‐Associated Macrophages with Biomaterials

(2019) Meilyn Sylvestre et al.   ADVANCED MATERIALS

Selectively targeting tumor-associated macrophages and tumor cells with polymeric micelles for enhanced cancer chemo-immunotherapy

(2019) Xiao Wei et al.   JOURNAL OF CONTROLLED RELEASE

Nanoparticle‐Embedded Electrospun Fiber–Covered Stent to Assist Intraluminal Photodynamic Treatment of Oesophageal Cancer

(2019) Junyuan Xiao et al.   Small

Understanding the tumor immune microenvironment (TIME) for effective therapy

(2018) Mikhail Binnewies et al.   NATURE MEDICINE

From nano to micro to macro: Electrospun hierarchically structured polymeric fibers for biomedical applications

(2018) Guang Yang et al.   PROGRESS IN POLYMER SCIENCE

TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy

(2018) Christopher B. Rodell et al.   Nature Biomedical Engineering

Immune Checkpoint Inhibition Overcomes ADCP-Induced Immunosuppression by Macrophages

(2018) Shicheng Su et al.   CELL

In situ sprayed bioresponsive immunotherapeutic gel for post-surgical cancer treatment

(2018) Qian Chen et al.   Nature Nanotechnology

Targeting macrophages: therapeutic approaches in cancer

(2018) Luca Cassetta et al.   NATURE REVIEWS DRUG DISCOVERY

Targeting tumor associated macrophages (TAMs) via nanocarriers

(2017) Yuvraj Singh et al.   JOURNAL OF CONTROLLED RELEASE

Spatial Targeting of Tumor-Associated Macrophages and Tumor Cells with a pH-Sensitive Cluster Nanocarrier for Cancer Chemoimmunotherapy

(2017) Song Shen et al.   NANO LETTERS

Tumour-associated macrophages as treatment targets in oncology

(2017) Alberto Mantovani et al.   Nature Reviews Clinical Oncology

Tumor-associated macrophages: Potential therapeutic targets for anti-cancer therapy

(2016) Yoshihiro Komohara et al.   ADVANCED DRUG DELIVERY REVIEWS

A novel liposomal Clodronate depletes tumor-associated macrophages in primary and metastatic melanoma: Anti-angiogenic and anti-tumor effects

(2016) F. Piaggio et al.   JOURNAL OF CONTROLLED RELEASE

Local triple-combination therapy results in tumour regression and prevents recurrence in a colon cancer model

(2016) João Conde et al.   NATURE MATERIALS

Aptamers as targeted therapeutics: current potential and challenges

(2016) Jiehua Zhou et al.   NATURE REVIEWS DRUG DISCOVERY

Local microRNA delivery targets Palladin and prevents metastatic breast cancer

(2016) Avital Gilam et al.   Nature Communications

Bioresponsive materials

(2016) Yue Lu et al.   Nature Reviews Materials

Dual Targeted Immunotherapy via In Vivo Delivery of Biohybrid RNAi-Peptide Nanoparticles to Tumor-Associated Macrophages and Cancer Cells

(2015) João Conde et al.   ADVANCED FUNCTIONAL MATERIALS

Shape and size-dependent immune response to antigen-carrying nanoparticles

(2015) Sunny Kumar et al.   JOURNAL OF CONTROLLED RELEASE

Self-assembled RNA-triple-helix hydrogel scaffold for microRNA modulation in the tumour microenvironment

(2015) João Conde et al.   NATURE MATERIALS

Understanding Local Macrophage Phenotypes In Disease: Modulating macrophage function to treat cancer

(2015) Vincenzo Bronte et al.   NATURE MEDICINE

Implantable hydrogel embedded dark-gold nanoswitch as a theranostic probe to sense and overcome cancer multidrug resistance

(2015) João Conde et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The future of immune checkpoint therapy

(2015) P. Sharma et al.   SCIENCE

Biodegradation and biocompatibility of PLA and PLGA microspheres

(2012) James M. Anderson et al.   ADVANCED DRUG DELIVERY REVIEWS

Cancer immunotherapy comes of age

(2011) Ira Mellman et al.   NATURE

Phenotypic and functional plasticity of cells of innate immunity: macrophages, mast cells and neutrophils

(2011) Stephen J Galli et al.   NATURE IMMUNOLOGY

Macrophage Diversity Enhances Tumor Progression and Metastasis

(2010) Bin-Zhi Qian et al.   CELL

Tumor-Associated Macrophages and Survival in Classic Hodgkin's Lymphoma

(2010) Christian Steidl et al.   NEW ENGLAND JOURNAL OF MEDICINE