Immune-mediated attenuation of influenza illness after infection: opportunities and challenges

Variable seasonal influenza vaccine effectiveness across geographical regions, age groups and levels of vaccine antigenic similarity with circulating virus strains: A systematic review and meta-analysis of the evidence from test-negative design studies after the 2009/10 influenza pandemic

(2021) G.N. Okoli et al.   VACCINE

Sequential targeting of interferon pathways for increased host resistance to bacterial superinfection during influenza

(2021) Tarani Kanta Barman et al.   PLoS Pathogens

The impact of repeated vaccination using 10-year vaccination history on protection against influenza in older adults: a test-negative design study across the 2010/11 to 2015/16 influenza seasons in Ontario, Canada

(2020) Jeffrey C Kwong et al.   Eurosurveillance

Next-generation influenza vaccines: opportunities and challenges

(2020) Chih-Jen Wei et al.   NATURE REVIEWS DRUG DISCOVERY

Frailty Hinders Recovery From Influenza and Acute Respiratory Illness in Older Adults

(2020) Caitlin Lees et al.   JOURNAL OF INFECTIOUS DISEASES

Influenza vaccine–induced human bone marrow plasma cells decline within a year after vaccination

(2020) Carl W. Davis et al.   SCIENCE

Influenza Vaccine for Patients With High-risk Cardiovascular Disease

(2020) Manish M. Patel et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Influenza Pathogenesis: The Effect of Host Factors on Severity of Disease

(2019) Anshu P. Gounder et al.   JOURNAL OF IMMUNOLOGY

Neuraminidase, the forgotten surface antigen, emerges as an influenza vaccine target for broadened protection

(2019) Maryna C Eichelberger et al.   JOURNAL OF INFECTIOUS DISEASES

Birth Cohort Effects in Influenza Surveillance Data: Evidence that First Influenza Infection Affects Later Influenza-Associated Illness

(2019) Alicia P Budd et al.   JOURNAL OF INFECTIOUS DISEASES

Age-specific differences in the dynamics of protective immunity to influenza

(2019) Sylvia Ranjeva et al.   Nature Communications

Novel correlates of protection against pandemic H1N1 influenza A virus infection

(2019) Sophia Ng et al.   NATURE MEDICINE

Antibiotics-Driven Gut Microbiome Perturbation Alters Immunity to Vaccines in Humans

(2019) Thomas Hagan et al.   CELL

Clinical Presentation of Influenza in Children 6 to 35 Months of Age

(2019) Jasur Danier et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Role of Memory B Cells in Hemagglutinin-Specific Antibody Production Following Human Influenza A Virus Infection

(2019) Mark Y. Sangster et al.   Pathogens

Priming with MF59 adjuvanted versus nonadjuvanted seasonal influenza vaccines in children – A systematic review and a meta-analysis

(2019) Manish M. Patel et al.   VACCINE

Clinical characteristics and severity of influenza infections by virus type, subtype, and lineage: A systematic literature review

(2018) Saverio Caini et al.   Influenza and Other Respiratory Viruses

Outpatient Management of Fever and Neutropenia in Adults Treated for Malignancy: American Society of Clinical Oncology and Infectious Diseases Society of America Clinical Practice Guideline Update

(2018) Randy A. Taplitz et al.   JOURNAL OF CLINICAL ONCOLOGY

From Original Antigenic Sin to the Universal Influenza Virus Vaccine

(2018) Carole Henry et al.   TRENDS IN IMMUNOLOGY

Virulent PB1-F2 residues: effects on fitness of H1N1 influenza A virus in mice and changes during evolution of human influenza A viruses

(2018) Irina V. Alymova et al.   Scientific Reports

Extensive T cell cross-reactivity between diverse seasonal influenza strains in the ferret model

(2018) Adrian J. Reber et al.   Scientific Reports

Influenza vaccine effectiveness in preventing influenza-associated intensive care admissions and attenuating severe disease among adults in New Zealand 2012–2015

(2018) Mark G. Thompson et al.   VACCINE

The hidden burden of influenza: A review of the extra-pulmonary complications of influenza infection

(2017) Subhashini A. Sellers et al.   Influenza and Other Respiratory Viruses

Proinflammatory Cytokine Responses in Extra-Respiratory Tissues During Severe Influenza

(2017) Kirsty R Short et al.   JOURNAL OF INFECTIOUS DISEASES

The Doctrine of Original Antigenic Sin: Separating Good From Evil

(2017) Arnold S. Monto et al.   JOURNAL OF INFECTIOUS DISEASES

Contemporary H3N2 influenza viruses have a glycosylation site that alters binding of antibodies elicited by egg-adapted vaccine strains

(2017) Seth J. Zost et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Understanding immune responses to the influenza vaccine

(2016) Richard Webby   NATURE MEDICINE

Potent protection against H5N1 and H7N9 influenza via childhood hemagglutinin imprinting

(2016) Katelyn M. Gostic et al.   SCIENCE

Influenza vaccine effectiveness by test-negative design – Comparison of inpatient and outpatient settings

(2016) Shuo Feng et al.   VACCINE

Evaluation of Antihemagglutinin and Antineuraminidase Antibodies as Correlates of Protection in an Influenza A/H1N1 Virus Healthy Human Challenge Model

(2016) Matthew J. Memoli et al.   mBio

Review Article

(2015) Nancy H. L. Leung et al.   EPIDEMIOLOGY

Influenza virus-induced lung injury: pathogenesis and implications for treatment

(2015) Susanne Herold et al.   EUROPEAN RESPIRATORY JOURNAL

Influenza B viruses: not to be discounted

(2015) Carolien E van de Sandt et al.   Future Microbiology

Does Influenza Vaccination Modify Influenza Severity? Data on Older Adults Hospitalized With Influenza During the 2012−2013 Season in the United States

(2015) Carmen S. Arriola et al.   JOURNAL OF INFECTIOUS DISEASES

High Preexisting Serological Antibody Levels Correlate with Diversification of the Influenza Vaccine Response

(2015) Sarah F. Andrews et al.   JOURNAL OF VIROLOGY

Validation of the Wild-type Influenza A Human Challenge Model H1N1pdMIST: An A(H1N1)pdm09 Dose-Finding Investigational New Drug Study

(2014) Matthew J. Memoli et al.   CLINICAL INFECTIOUS DISEASES

Antibody landscapes after influenza virus infection or vaccination

(2014) J. M. Fonville et al.   SCIENCE

Efficacy of live attenuated influenza vaccine against influenza illness in children as a function of illness severity

(2014) Christopher S. Ambrose et al.   VACCINE

Influenza Vaccine Effectiveness in Preventing Outpatient, Inpatient, and Severe Cases of Laboratory-Confirmed Influenza

(2013) Jesús Castilla et al.   CLINICAL INFECTIOUS DISEASES

Cytokine responses in patients with mild or severe influenza A(H1N1)pdm09

(2013) A. Bradley-Stewart et al.   JOURNAL OF CLINICAL VIROLOGY

Immune Dysfunction and Bacterial Coinfections following Influenza

(2013) D. W. Metzger et al.   JOURNAL OF IMMUNOLOGY

Antibody Correlates and Predictors of Immunity to Naturally Occurring Influenza in Humans and the Importance of Antibody to the Neuraminidase

(2013) Robert B. Couch et al.   JOURNAL OF INFECTIOUS DISEASES

Pathogenesis of influenza-induced acute respiratory distress syndrome

(2013) Kirsty R Short et al.   LANCET INFECTIOUS DISEASES

Vaccine for Prevention of Mild and Moderate-to-Severe Influenza in Children

(2013) Varsha K. Jain et al.   NEW ENGLAND JOURNAL OF MEDICINE

Populations at risk for severe or complicated influenza illness: systematic review and meta-analysis

(2013) D. Mertz et al.   BMJ-British Medical Journal

Correlates of protection to influenza virus, where do we go from here?

(2013) Rebecca Cox   Human Vaccines & Immunotherapeutics

Experimental human influenza: observations from studies of influenza antivirals

(2012) Frederick G Hayden   ANTIVIRAL THERAPY

A review on the clinical spectrum and natural history of human influenza

(2012) Warunee Punpanich et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Preexisting influenza-specific CD4+ T cells correlate with disease protection against influenza challenge in humans

(2012) Tom M Wilkinson et al.   NATURE MEDICINE

Mortality Burden of the 2009 A/H1N1 Influenza Pandemic in France: Comparison to Seasonal Influenza and the A/H3N2 Pandemic

(2012) Magali Lemaitre et al.   PLoS One

Pandemic H1N1 influenza vaccine induces a recall response in humans that favors broadly cross-reactive memory B cells

(2012) G.-M. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hemagglutinin stalk antibodies elicited by the 2009 pandemic influenza virus as a mechanism for the extinction of seasonal H1N1 viruses

(2012) N. Pica et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mucosal IgA responses in influenza virus infections; thoughts for vaccine design

(2012) Elly van Riet et al.   VACCINE

Evidence for Antigenic Seniority in Influenza A (H3N2) Antibody Responses in Southern China

(2012) Justin Lessler et al.   PLoS Pathogens

Risk Factors for Severe Outcomes following 2009 Influenza A (H1N1) Infection: A Global Pooled Analysis

(2011) Maria D. Van Kerkhove et al.   PLOS MEDICINE

2009 Pandemic Influenza A (H1N1)

(2010) Wun-Ju Shieh et al.   AMERICAN JOURNAL OF PATHOLOGY

Estimating the Burden of 2009 Pandemic Influenza A (H1N1) in the United States (April 2009-April 2010)

(2010) S. S. Shrestha et al.   CLINICAL INFECTIOUS DISEASES

Association of Profoundly Impaired Immune Competence in H1N1v‐Infected Patients with a Severe or Fatal Clinical Course

(2010) Chiara Agrati et al.   JOURNAL OF INFECTIOUS DISEASES

Cross-Reactive Antibody Responses to the 2009 Pandemic H1N1 Influenza Virus

(2009) Kathy Hancock et al.   NEW ENGLAND JOURNAL OF MEDICINE

Booster Vaccinations: Can Immunologic Memory Outpace Disease Pathogenesis?

(2009) M. E. Pichichero   PEDIATRICS

Pre-existing immunity against swine-origin H1N1 influenza viruses in the general human population

(2009) J. A. Greenbaum et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Time Lines of Infection and Disease in Human Influenza: A Review of Volunteer Challenge Studies

(2008) Fabrice Carrat et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

The Pathology of Influenza Virus Infections

(2008) Jeffery K. Taubenberger et al.   Annual Review of Pathology-Mechanisms of Disease

Heterosubtypic immunity to influenza A virus: where do we stand?

(2008) Kristie M. Grebe et al.   MICROBES AND INFECTION

Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors

(2008) Xiaocong Yu et al.   NATURE