Role of Memory B Cells in Hemagglutinin-Specific Antibody Production Following Human Influenza A Virus Infection

The Multifaceted B Cell Response to Influenza Virus

(2019) Jonathan H. Lam et al.   JOURNAL OF IMMUNOLOGY

Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses

(2019) Masaru Kanekiyo et al.   NATURE IMMUNOLOGY

Broad hemagglutinin-specific memory B cell expansion by seasonal influenza virus infection reflects early-life imprinting and adaptation to the infecting virus

(2019) Brenda L. Tesini et al.   JOURNAL OF VIROLOGY

Assessing the protective potential of H1N1 influenza virus hemagglutinin head and stalk antibodies in humans

(2019) Shannon R. Christensen et al.   JOURNAL OF VIROLOGY

B Cell Responses: Cell Interaction Dynamics and Decisions

(2019) Jason G. Cyster et al.   CELL

Activation Dynamics and Immunoglobulin Evolution of Pre-existing and Newly Generated Human Memory B cell Responses to Influenza Hemagglutinin

(2019) Sarah F. Andrews et al.   IMMUNITY

Outflanking immunodominance to target subdominant broadly neutralizing epitopes

(2019) Davide Angeletti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A mosaic hemagglutinin-based influenza virus vaccine candidate protects mice from challenge with divergent H3N2 strains

(2019) Felix Broecker et al.   npj Vaccines

Prolonged evolution of the memory B cell response induced by a replicating adenovirus-influenza H5 vaccine

(2019) Kenta Matsuda et al.   Science Immunology

Immunological responses to influenza vaccination: lessons for improving vaccine efficacy

(2018) Taia T .Wang et al.   CURRENT OPINION IN IMMUNOLOGY

Pandemic influenza vaccines: what they have taught us about B cell immunology

(2018) David J Topham et al.   CURRENT OPINION IN IMMUNOLOGY

Generation of memory B cells and their reactivation

(2018) Takeshi Inoue et al.   IMMUNOLOGICAL REVIEWS

Strength in diversity: Phenotypic, functional, and molecular heterogeneity within the memory B cell repertoire

(2018) Kim L. Good-Jacobson   IMMUNOLOGICAL REVIEWS

Intranasal Live Influenza Vaccine Priming Elicits Localized B Cell Responses in Mediastinal Lymph Nodes

(2018) Sinthujan Jegaskanda et al.   JOURNAL OF VIROLOGY

Structural insights into the design of novel anti-influenza therapies

(2018) Nicholas C. Wu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

From Original Antigenic Sin to the Universal Influenza Virus Vaccine

(2018) Carole Henry et al.   TRENDS IN IMMUNOLOGY

Influenza Hemagglutinin Protein Stability, Activation, and Pandemic Risk

(2018) Charles J. Russell et al.   TRENDS IN MICROBIOLOGY

NAction! How Can Neuraminidase-Based Immunity Contribute to Better Influenza Virus Vaccines?

(2018) Florian Krammer et al.   mBio

Structural insights into the design of novel anti-influenza therapies

(2018) Nicholas C. Wu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Memory B cells are reactivated in subcapsular proliferative foci of lymph nodes

(2018) Imogen Moran et al.   Nature Communications

Spatiotemporal segregation of human marginal zone and memory B cell populations in lymphoid tissue

(2018) Yuan Zhao et al.   Nature Communications

Immunodominance and antigenic variation of influenza virus hemagglutinin: implications for design of universal vaccine immunogens

(2018) Seth J Zost et al.   JOURNAL OF INFECTIOUS DISEASES

Subcapsular Sinus Macrophages: The Seat of Innate and Adaptive Memory in Murine Lymph Nodes

(2018) Imogen Moran et al.   TRENDS IN IMMUNOLOGY

Induction of Broadly Cross-Reactive Stalk-Specific Antibody Responses to Influenza Group 1 and Group 2 Hemagglutinins by Natural H7N9 Virus Infection in Humans

(2017) Lu Liu et al.   JOURNAL OF INFECTIOUS DISEASES

Do Memory B Cells Form Secondary Germinal Centers?

(2017) Mark J. Shlomchik   Cold Spring Harbor Perspectives in Biology

Immune history and influenza virus susceptibility

(2017) Sarah Cobey et al.   Current Opinion in Virology

Epitope-Specific Suppression of IgG Responses by Passively Administered Specific IgG: Evidence of Epitope Masking

(2017) Joakim J. E. Bergström et al.   Frontiers in Immunology

Vaccination with a Recombinant H7 Hemagglutinin-Based Influenza Virus Vaccine Induces Broadly Reactive Antibodies in Humans

(2017) Daniel Stadlbauer et al.   mSphere

Heads, stalks and everything else: how can antibodies eradicate influenza as a human disease?

(2016) Karlynn E Neu et al.   CURRENT OPINION IN IMMUNOLOGY

Germinal Center B Cell Dynamics

(2016) Luka Mesin et al.   IMMUNITY

A Temporal Switch in the Germinal Center Determines Differential Output of Memory B and Plasma Cells

(2016) Florian J. Weisel et al.   IMMUNITY

Directed selection of influenza virus produces antigenic variants that match circulating human virus isolates and escape from vaccine-mediated immune protection

(2016) Marta L. DeDiego et al.   IMMUNOLOGY

Defining antigen-specific plasmablast and memory B cell subsets in human blood after viral infection or vaccination

(2016) Ali H Ellebedy et al.   NATURE IMMUNOLOGY

Visualizing antibody affinity maturation in germinal centers

(2016) J. M. J. Tas et al.   SCIENCE

Potent protection against H5N1 and H7N9 influenza via childhood hemagglutinin imprinting

(2016) Katelyn M. Gostic et al.   SCIENCE

Antigen Presentation to B Cells

(2016) Balthasar A. Heesters et al.   TRENDS IN IMMUNOLOGY

Germinal Center Selection and the Antibody Response to Influenza

(2015) Gabriel D. Victora et al.   CELL

Tissue Distribution of Memory T and B Cells in Rhesus Monkeys following Influenza A Infection

(2015) Sathit Pichyangkul et al.   JOURNAL OF IMMUNOLOGY

Hemagglutinin-stem nanoparticles generate heterosubtypic influenza protection

(2015) Hadi M Yassine et al.   NATURE MEDICINE

Masking of antigenic epitopes by antibodies shapes the humoral immune response to influenza

(2015) Veronika I. Zarnitsyna et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Immune history profoundly affects broadly protective B cell responses to influenza

(2015) Sarah F. Andrews et al.   Science Translational Medicine

Virus-Specific Antibody Secreting Cell, Memory B-cell, and Sero-Antibody Responses in the Human Influenza Challenge Model

(2014) Kuan-Ying Arthur Huang et al.   JOURNAL OF INFECTIOUS DISEASES

Induction of broadly cross-reactive antibody responses to the influenza HA stem region following H5N1 vaccination in humans

(2014) A. H. Ellebedy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antibody landscapes after influenza virus infection or vaccination

(2014) J. M. Fonville et al.   SCIENCE

B Cell Response and Hemagglutinin Stalk-Reactive Antibody Production in Different Age Cohorts following 2009 H1N1 Influenza Virus Vaccination

(2013) Mark Y. Sangster et al.   Clinical and Vaccine Immunology

Germinal center B cells govern their own fate via antibody feedback

(2013) Yang Zhang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Influenza virus hemagglutinin stalk-based antibodies and vaccines

(2013) Florian Krammer et al.   Current Opinion in Virology

Distinct cellular pathways select germline-encoded and somatically mutated antibodies into immunological memory

(2012) Tomohiro Kaji et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Pandemic H1N1 influenza vaccine induces a recall response in humans that favors broadly cross-reactive memory B cells

(2012) G.-M. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Broadly neutralizing antibodies against influenza virus and prospects for universal therapies

(2012) Damian C Ekiert et al.   Current Opinion in Virology

Evidence for Antigenic Seniority in Influenza A (H3N2) Antibody Responses in Southern China

(2012) Justin Lessler et al.   PLoS Pathogens

Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection

(2011) Jens Wrammert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A dynamic T cell–limited checkpoint regulates affinity-dependent B cell entry into the germinal center

(2011) Tanja A. Schwickert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

H3N2 Influenza Infection Elicits More Cross-Reactive and Less Clonally Expanded Anti-Hemagglutinin Antibodies Than Influenza Vaccination

(2011) M. Anthony Moody et al.   PLoS One

B cell follicles and antigen encounters of the third kind

(2010) Jason G Cyster   NATURE IMMUNOLOGY

Preferential localization of IgG memory B cells adjacent to contracted germinal centers

(2010) Y. Aiba et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Buying Time—The Immune System Determinants of the Incubation Period to Respiratory Viruses

(2010) Tamar Hermesh et al.   Viruses-Basel

Biodistribution Mechanisms of Therapeutic Monoclonal Antibodies in Health and Disease

(2009) Mohammad Tabrizi et al.   AAPS Journal

Antigen Affinity Controls Rapid T-Dependent Antibody Production by Driving the Expansion Rather than the Differentiation or Extrafollicular Migration of Early Plasmablasts

(2009) T. D. Chan et al.   JOURNAL OF IMMUNOLOGY

Broad dispersion and lung localization of virus-specific memory B cells induced by influenza pneumonia

(2008) H. M. Joo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA