Combination of ionising radiation with hyperthermia increases the immunogenic potential of B16-F10 melanoma cells in vitro and in vivo

Targeting the heat shock response in combination with radiotherapy: Sensitizing cancer cells to irradiation-induced cell death and heating up their immunogenicity

(2015) Kirsten Lauber et al.   CANCER LETTERS

Contribution of the immune system to bystander and non-targeted effects of ionizing radiation

(2015) Franz Rödel et al.   CANCER LETTERS

Sensitizing tumor cells to radiation by targeting the heat shock response

(2015) Daniela Schilling et al.   CANCER LETTERS

The role of heat shock protein 70 (Hsp70) in radiation-induced immunomodulation

(2015) Gabriele Multhoff et al.   CANCER LETTERS

Local hyperthermia combined with radiotherapy and-/or chemotherapy: Recent advances and promises for the future

(2015) N.R. Datta et al.   CANCER TREATMENT REVIEWS

Radiotherapy for cutaneous melanoma: current and future applications

(2015) Peter Gorayski et al.   Future Oncology

Enhanced tumour regression in a patient of liposarcoma treated with radiotherapy and hyperthermia: Hint for dynamic immunomodulation by hyperthermia

(2015) Niloy Ranjan Datta et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Hyperthermia effects on Hsp27 and Hsp72 associations with mismatch repair (MMR) proteins and cisplatin toxicity in MMR-deficient/proficient colon cancer cell lines

(2015) Mayra L. Sottile et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Increased anti-tumour activity by exosomes derived from doxorubicin-treated tumour cells via heat stress

(2015) Yunshan Yang et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Hyperthermia-related clinical trials on cancer treatment within the ClinicalTrials.gov registry

(2015) Nikola Cihoric et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Radio-immunotherapy: the focused beam expands

(2015) Benjamin Frey et al.   LANCET ONCOLOGY

Local radiotherapy and granulocyte-macrophage colony-stimulating factor to generate abscopal responses in patients with metastatic solid tumours: a proof-of-principle trial

(2015) Encouse B Golden et al.   LANCET ONCOLOGY

The non-targeted effects of radiation are perpetuated by exosomes

(2015) Ammar Al-Mayah et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer

(2015) Christina Twyman-Saint Victor et al.   NATURE

Immune Checkpoint Inhibitors in Melanoma Provide the Cornerstones for Curative Therapies

(2015) Alexander M.M. Eggermont et al.   SEMINARS IN ONCOLOGY

Radiotherapy and immune checkpoint blockade: potential interactions and future directions

(2015) David C. Binder et al.   TRENDS IN MOLECULAR MEDICINE

Modulation of radiochemoimmunotherapy-induced B16 melanoma cell death by the pan-caspase inhibitor zVAD-fmk induces anti-tumor immunity in a HMGB1-, nucleotide- and T-cell-dependent manner

(2015) N Werthmöller et al.   Cell Death & Disease

In-situ tumor vaccination: Bringing the fight to the tumor

(2015) Robert H Pierce et al.   Human Vaccines & Immunotherapeutics

Acquired Resistance to Fractionated Radiotherapy Can Be Overcome by Concurrent PD-L1 Blockade

(2014) S. J. Dovedi et al.   CANCER RESEARCH

Local tumour hyperthermia as immunotherapy for metastatic cancer

(2014) Seiko Toraya-Brown et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Combinations of Radiation Therapy and Immunotherapy for Melanoma: A Review of Clinical Outcomes

(2014) Christopher A. Barker et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Immunological aspects of radiotherapy

(2014) Heike Scheithauer et al.   Radiation Oncology

Hyperthermia, Radiation and Chemotherapy: The Role of Heat in Multidisciplinary Cancer Care

(2014) Mark Hurwitz et al.   SEMINARS IN ONCOLOGY

DNA fragmentation and caspase-independent programmed cell death by modulated electrohyperthermia

(2014) N. Meggyeshazi et al.   STRAHLENTHERAPIE UND ONKOLOGIE

Combinations of Immunotherapy and Radiation in Cancer Therapy

(2014) Ralph E. Vatner et al.   Frontiers in Oncology

Antitumor immune responses induced by ionizing irradiation and further immune stimulation

(2013) Benjamin Frey et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Intracellular and extracellular Hsp70 chaperone as a target for cancer therapy

(2013) Irina V. Guzhova et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Signatures of mutational processes in human cancer

(2013) Ludmil B. Alexandrov et al.   NATURE

Current concepts in clinical radiation oncology

(2013) Michael Orth et al.   RADIATION AND ENVIRONMENTAL BIOPHYSICS

Temperature Matters! And Why It Should Matter to Tumor Immunologists

(2013) E. A. Repasky et al.   Cancer Immunology Research

Radiotherapy in conjunction with superficial and intracavitary hyperthermia for the treatment of solid tumors: survival and thermal parameters

(2012) S. Triantopoulou et al.   Clinical & Translational Oncology

Old and new facts about hyperthermia-induced modulations of the immune system

(2012) Benjamin Frey et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Effector CD8+T cell IFN-γproduction and cytotoxicity are enhanced by mild hyperthermia

(2012) Thomas A. Mace et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Melanoma-induced immunosuppression and its neutralization

(2012) Viktor Umansky et al.   SEMINARS IN CANCER BIOLOGY

Sensitization to the mitochondrial pathway of apoptosis augments melanoma tumor cell responses to conventional chemotherapeutic regimens

(2012) R A Anvekar et al.   Cell Death & Disease

Dying cell clearance and its impact on the outcome of tumor radiotherapy

(2012) Kirsten Lauber et al.   Frontiers in Oncology

Mild hyperthermia inhibits homologous recombination, induces BRCA2 degradation, and sensitizes cancer cells to poly (ADP-ribose) polymerase-1 inhibition

(2011) P. M. Krawczyk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Radiation combined with hyperthermia induces HSP70-dependent maturation of dendritic cells and release of pro-inflammatory cytokines by dendritic cells and macrophages

(2011) Petra Schildkopf et al.   RADIOTHERAPY AND ONCOLOGY

High-mobility group box 1 and cancer

(2010) Daolin Tang et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Combination of Ionising Irradiation and Hyperthermia Activates Programmed Apoptotic and Necrotic Cell Death Pathways in Human Colorectal Carcinoma Cells

(2010) Frederick Mantel et al.   STRAHLENTHERAPIE UND ONKOLOGIE

Application of hyperthermia in addition to ionizing irradiation fosters necrotic cell death and HMGB1 release of colorectal tumor cells

(2009) Petra Schildkopf et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Heat shock proteins and immunity: Application of hyperthermia for immunomodulation

(2009) Toshihiko Torigoe et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

HMGB1 Mediates Endogenous TLR2 Activation and Brain Tumor Regression

(2009) James F Curtin et al.   PLOS MEDICINE

Hyperthermia adds to chemotherapy

(2008) Rolf D. Issels   EUROPEAN JOURNAL OF CANCER