Old and new facts about hyperthermia-induced modulations of the immune system

Induction of Abscopal Anti-Tumor Immunity and Immunogenic Tumor Cell Death by Ionizing Irradiation - Implications for Cancer Therapies

(2012) B. Frey et al.   CURRENT MEDICINAL CHEMISTRY

Prerequisites for the Antitumor Vaccine-Like Effect of Chemotherapy and Radiotherapy

(2011) Dalil Hannani et al.   CANCER JOURNAL

Toward establishment of temperature thresholds for immunological impact of heat exposure in humans

(2011) Sarah H. Beachy et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Mild hyperthermia enhances human monocyte-derived dendritic cell functions and offers potential for applications in vaccination strategies

(2011) Ilka Knippertz et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Chemokine-Containing Exosomes Are Released from Heat-Stressed Tumor Cells via Lipid Raft-Dependent Pathway and Act as Efficient Tumor Vaccine

(2011) T. Chen et al.   JOURNAL OF IMMUNOLOGY

Helper Activity of Natural Killer Cells During the Dendritic Cell-mediated Induction of Melanoma-specific Cytotoxic T Cells

(2011) Jeffrey L. Wong et al.   JOURNAL OF IMMUNOTHERAPY

Mild hyperthermia inhibits homologous recombination, induces BRCA2 degradation, and sensitizes cancer cells to poly (ADP-ribose) polymerase-1 inhibition

(2011) P. M. Krawczyk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Radiation combined with hyperthermia induces HSP70-dependent maturation of dendritic cells and release of pro-inflammatory cytokines by dendritic cells and macrophages

(2011) Petra Schildkopf et al.   RADIOTHERAPY AND ONCOLOGY

Quality assurance for clinical studies in regional deep hyperthermia

(2011) Gregor Bruggmoser et al.   STRAHLENTHERAPIE UND ONKOLOGIE

High-mobility group box 1 and cancer

(2010) Daolin Tang et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Biological Rationales and Clinical Applications of Temperature Controlled Hyperthermia - Implications for Multimodal Cancer Treatments

(2010) P. Schildkopf et al.   CURRENT MEDICINAL CHEMISTRY

Heat shock proteins in prostate cancer: from tumorigenesis to the clinic

(2010) Daniel R. Ciocca et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Activation of Caspase-9, but Not Caspase-2 or Caspase-8, Is Essential for Heat-induced Apoptosis in Jurkat Cells

(2010) Shary N. Shelton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neo-adjuvant chemotherapy alone or with regional hyperthermia for localised high-risk soft-tissue sarcoma: a randomised phase 3 multicentre study

(2010) Rolf D Issels et al.   LANCET ONCOLOGY

Radiation therapy induces circulating serum Hsp72 in patients with prostate cancer

(2010) Mark D. Hurwitz et al.   RADIOTHERAPY AND ONCOLOGY

The immune functions of phosphatidylserine in membranes of dying cells and microvesicles

(2010) Benjamin Frey et al.   Seminars in Immunopathology

Combination of Ionising Irradiation and Hyperthermia Activates Programmed Apoptotic and Necrotic Cell Death Pathways in Human Colorectal Carcinoma Cells

(2010) Frederick Mantel et al.   STRAHLENTHERAPIE UND ONKOLOGIE

Hyperthermia in combination with X-irradiation induces inflammatory forms of cell death

(2009) Petra Schildkopf et al.   AUTOIMMUNITY

Application of hyperthermia in addition to ionizing irradiation fosters necrotic cell death and HMGB1 release of colorectal tumor cells

(2009) Petra Schildkopf et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Treating human cancers with heat shock protein-peptide complexes: the road ahead

(2009) Pramod K Srivastava et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Kinetics study on markers of the immune system by gene expression profiling of anin vivoheated tumor

(2009) Erling Dahl Borkamo et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Heat shock proteins and immunity: Application of hyperthermia for immunomodulation

(2009) Toshihiko Torigoe et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Local hyperthermia could induce migrational maturation of Langerhans cells in condyloma acuminatum

(2009) Xiaodong Li et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

AnnexinA5 renders dead tumor cells immunogenic—implications for multimodal cancer therapies

(2009) Benjamin Frey et al.   Journal of Immunotoxicology

Hyperthermia on immune regulation: A temperature’s story

(2008) Hua-Gang Zhang et al.   CANCER LETTERS

Structural Basis for the Cooperation of Hsp70 and Hsp110 Chaperones in Protein Folding

(2008) Sigrun Polier et al.   CELL

Influence of Hsp70 and HLA-E on the killing of leukemic blasts by cytokine/Hsp70 peptide-activated human natural killer (NK) cells

(2008) Stefan Stangl et al.   CELL STRESS & CHAPERONES

Hyperthermia adds to chemotherapy

(2008) Rolf D. Issels   EUROPEAN JOURNAL OF CANCER

DNA double strand break repair inhibition as a cause of heat radiosensitization: Re-evaluation considering backup pathways of NHEJ

(2008) George Iliakis et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Dissecting the role of hyperthermia in natural killer cell mediated anti-tumor responses

(2008) Baris E. Dayanc et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Phase III Comparison of Vitespen, an Autologous Tumor-Derived Heat Shock Protein gp96 Peptide Complex Vaccine, With Physician's Choice of Treatment for Stage IV Melanoma: The C-100-21 Study Group

(2008) Alessandro Testori et al.   JOURNAL OF CLINICAL ONCOLOGY

An adjuvant autologous therapeutic vaccine (HSPPC-96; vitespen) versus observation alone for patients at high risk of recurrence after nephrectomy for renal cell carcinoma: a multicentre, open-label, randomised phase III trial

(2008) Christopher Wood et al.   LANCET

Tumor-Specific Hsp70 Plasma Membrane Localization Is Enabled by the Glycosphingolipid Gb3

(2008) Mathias Gehrmann et al.   PLoS One