Loading of DOX into a tetrahedral DNA nanostructure: the corner does matter

Unraveling the interaction between doxorubicin and DNA origami nanostructures for customizable chemotherapeutic drug release

(2021) Heini Ijäs et al.   NUCLEIC ACIDS RESEARCH

Improving the Performance of MM/PBSA in Protein–Protein Interactions via the Screening Electrostatic Energy

(2021) Yan-jing Sheng et al.   Journal of Chemical Information and Modeling

The HDOCK server for integrated protein–protein docking

(2020) Yumeng Yan et al.   Nature Protocols

DNA hydrogel-based gene editing and drug delivery systems

(2020) Fangli Mo et al.   ADVANCED DRUG DELIVERY REVIEWS

Tetrahedral DNA nanostructures as drug delivery and bioimaging platforms in cancer therapy

(2020) Ratchanee Duangrat et al.   CANCER SCIENCE

Design, fabrication and applications of tetrahedral DNA nanostructure-based multifunctional complexes in drug delivery and biomedical treatment

(2020) Tao Zhang et al.   Nature Protocols

Gint4.T-Modified DNA Tetrahedrons Loaded with Doxorubicin Inhibits Glioma Cell Proliferation by Targeting PDGFRβ

(2020) Feng Wang et al.   Nanoscale Research Letters

The Product of Matrix Metalloproteinase Cleavage of Doxorubicin Conjugate for Anticancer Drug Delivery: Calorimetric, Spectroscopic, and Molecular Dynamics Studies on Peptide–Doxorubicin Binding to DNA

(2020) Kamila Butowska et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

DNA Framework-Programmed Cell Capture via Topology-Engineered Receptor–Ligand Interactions

(2019) Min Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Assessing the performance of MM/PBSA and MM/GBSA methods. 8. Predicting binding free energies and poses of protein-RNA complexes

(2018) Fu Chen et al.   RNA

A self-assembled nanoscale robotic arm controlled by electric fields

(2018) Enzo Kopperger et al.   SCIENCE

DNA Nanostructure-Programmed Like-Charge Attraction at the Cell-Membrane Interface

(2018) Hongming Ding et al.   ACS Central Science

A Tailored DNA Nanoplatform for Synergistic RNAi-/Chemotherapy of Multidrug-Resistant Tumors

(2018) Jianbing Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Measuring the Conformation and Persistence Length of Single-Stranded DNA Using a DNA Origami Structure

(2018) Efrat Roth et al.   NANO LETTERS

Binding of anticancer drug daunomycin to a TGGGGT G-quadruplex DNA probed by all-atom molecular dynamics simulations: additional pure groove binding mode and implications on designing more selective G-quadruplex ligands

(2017) Zhanhang Shen et al.   JOURNAL OF MOLECULAR MODELING

Synthesis of an ethyleneimine/tetrahedral DNA nanostructure complex and its potential application as a multi-functional delivery vehicle

(2017) Taoran Tian et al.   Nanoscale

HDOCK: a web server for protein–protein and protein–DNA/RNA docking based on a hybrid strategy

(2017) Yumeng Yan et al.   NUCLEIC ACIDS RESEARCH

Improvements to the APBS biomolecular solvation software suite

(2017) Elizabeth Jurrus et al.   PROTEIN SCIENCE

Tumor-Penetrating Peptide-Modified DNA Tetrahedron for Targeting Drug Delivery

(2016) Zhiwei Xia et al.   BIOCHEMISTRY

Functional nucleic acid-based hydrogels for bioanalytical and biomedical applications

(2016) Juan Li et al.   CHEMICAL SOCIETY REVIEWS

Aptamer-integrated DNA nanostructures for biosensing, bioimaging and cancer therapy

(2016) Hong-Min Meng et al.   CHEMICAL SOCIETY REVIEWS

A Simple and Fast Semiautomatic Procedure for the Atomistic Modeling of Complex DNA Polyhedra

(2016) Cassio Alves et al.   Journal of Chemical Information and Modeling

Self-assembled mirror DNA nanostructures for tumor-specific delivery of anticancer drugs

(2016) Kyoung-Ran Kim et al.   JOURNAL OF CONTROLLED RELEASE

Dual-Reporter Drift Correction To Enhance the Performance of Electrochemical Aptamer-Based Sensors in Whole Blood

(2016) Hui Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Electrochemical detection of nucleic acids, proteins, small molecules and cells using a DNA-nanostructure-based universal biosensing platform

(2016) Meihua Lin et al.   Nature Protocols

Nanocaged enzymes with enhanced catalytic activity and increased stability against protease digestion

(2016) Zhao Zhao et al.   Nature Communications

A study of pH-dependence of shrink and stretch of tetrahedral DNA nanostructures

(2015) Ping Wang et al.   Nanoscale

Parmbsc1: a refined force field for DNA simulations

(2015) Ivan Ivani et al.   NATURE METHODS

DNA Origami as an In Vivo Drug Delivery Vehicle for Cancer Therapy

(2014) Qian Zhang et al.   ACS Nano

Integration of Nanoassembly Functions for an Effective Delivery Cascade for Cancer Drugs

(2014) Qihang Sun et al.   ADVANCED MATERIALS

Hybridization Chain Reaction Amplification of MicroRNA Detection with a Tetrahedral DNA Nanostructure-Based Electrochemical Biosensor

(2014) Zhilei Ge et al.   ANALYTICAL CHEMISTRY

i-Motif DNA: Structure, stability and targeting with ligands

(2014) Henry A. Day et al.   BIOORGANIC & MEDICINAL CHEMISTRY

New Insights into the Mechanism of the DNA/Doxorubicin Interaction

(2014) Cristina Pérez-Arnaiz et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Functional DNA Nanostructures for Theranostic Applications

(2013) Hao Pei et al.   ACCOUNTS OF CHEMICAL RESEARCH

Smart Drug Delivery Nanocarriers with Self-Assembled DNA Nanostructures

(2013) Jiang Li et al.   ADVANCED MATERIALS

DNA Origami Delivery System for Cancer Therapy with Tunable Release Properties

(2012) Yong-Xing Zhao et al.   ACS Nano

Early stage intercalation of doxorubicin to DNA fragments observed in molecular dynamics binding simulations

(2012) Hongxing Lei et al.   JOURNAL OF MOLECULAR GRAPHICS & MODELLING

Doxorubicin: an update on anticancer molecular action, toxicity and novel drug delivery systems

(2012) Oktay Tacar et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Free Energy Calculations by the Molecular Mechanics Poisson−Boltzmann Surface Area Method

(2012) Nadine Homeyer et al.   Molecular Informatics

Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery

(2012) Hyukjin Lee et al.   Nature Nanotechnology

DNA secondary structures: stability and function of G-quadruplex structures

(2012) Matthew L. Bochman et al.   NATURE REVIEWS GENETICS

DNA Cage Delivery to Mammalian Cells

(2011) Anthony S. Walsh et al.   ACS Nano

DNA Origami with Complex Curvatures in Three-Dimensional Space

(2011) D. Han et al.   SCIENCE

Structure of Nanoscale Truncated Octahedral DNA Cages: Variation of Single-Stranded Linker Regions and Influence on Assembly Yields

(2010) Cristiano Luis Pinto Oliveira et al.   ACS Nano

Doxorubicin: The Good, the Bad and the Ugly Effect

(2009) Cristina Carvalho et al.   CURRENT MEDICINAL CHEMISTRY

High-Resolution Structural Analysis of a DNA Nanostructure by cryoEM

(2009) Takayuki Kato et al.   NANO LETTERS

DNA Nanotubes as Combinatorial Vehicles for Cellular Delivery

(2008) SeungHyeon Ko et al.   BIOMACROMOLECULES