Synthesis and Characterization of Novel 2-Acyl-3-trifluoromethylquinoxaline 1,4-Dioxides as Potential Antimicrobial Agents

Novel strategies in the war against antibiotic resistance

(2021) Stella Cascioferro et al.   Future Medicinal Chemistry

The Spectrum of Antimicrobial Activity of Cyadox against Pathogens Collected from Pigs, Chicken, and Fish in China

(2021) Muhammad Kashif Maan et al.   Antibiotics-Basel

Discovery of novel nitrogenous heterocyclic-containing quinoxaline-1,4-di-N-oxides as potent activator of autophagy in M.tb-infected macrophages

(2021) Heying Zhang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

MmpS5-MmpL5 Transporters Provide Mycobacterium smegmatis Resistance to imidazo[1,2-b][1,2,4,5]tetrazines

(2020) Dmitry A. Maslov et al.   Pathogens

Therapeutic strategies to counteract antibiotic resistance in MRSA biofilm‐associated infections

(2020) Stella Cascioferro et al.   ChemMedChem

Identification of Mutations Conferring Tryptanthrin Resistance to Mycobacterium smegmatis

(2020) Svetlana G. Frolova et al.   Antibiotics-Basel

The compound TB47 is highly bactericidal against Mycobacterium ulcerans in a Buruli ulcer mouse model

(2019) Yang Liu et al.   Nature Communications

Discovery and Biosynthesis of Atrovimycin, an Antitubercular and Antifungal Cyclodepsipeptide Featuring Vicinal-dihydroxylated Cinnamic Acyl Chain

(2019) Qing Liu et al.   ORGANIC LETTERS

The “Old” and the “New” Antibiotics for MDR Gram-Negative Pathogens: For Whom, When, and How

(2019) Ilias Karaiskos et al.   Frontiers in Public Health

Synthesis and antimycobacterial activity of imidazo[1,2-b][1,2,4,5]tetrazines

(2019) Dmitry A. Maslov et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Revision of the Regioselectivity of the Beirut Reaction of Monosubstituted Benzofuroxans with Benzoylacetonitrile. 6-Substituted quinoxaline-2-carbonitrile 1,4- dioxides: Structural Characterization and Estimation of Anticancer Activity and Hypoxia Selectivity

(2019) Galina I. Buravchenko et al.   CURRENT ORGANIC SYNTHESIS

Cryochemical modification, activity, and toxicity of dioxidine

(2017) O. I. Vernaya et al.   Russian Journal of Physical Chemistry A

Sorting out antibiotics' mechanisms of action: a double fluorescent protein reporter for high throughput screening of ribosome and DNA biosynthesis inhibitors

(2016) Ilya A. Osterman et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Synthesis and biological evaluation of quinoxaline di- N -oxide derivatives with in vitro trypanocidal activity

(2016) Silvia Pérez-Silanes et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Design and synthesis of novel quinoxaline derivatives as potential candidates for treatment of multidrug-resistant and latent tuberculosis

(2016) Mery Santivañez-Veliz et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Dioxidine induces bacterial resistance to antibiotics

(2016) M. S. Mazanko et al.   Molecular Genetics Microbiology and Virology

Quinoxaline 1,4-di-N-Oxides: Biological Activities and Mechanisms of Actions

(2016) Guyue Cheng et al.   Frontiers in Pharmacology

Comprehensive Definition of the SigH Regulon of Mycobacterium tuberculosis Reveals Transcriptional Control of Diverse Stress Responses

(2016) Jared D. Sharp et al.   PLoS One

Systematic and Molecular Basis of the Antibacterial Action of Quinoxaline 1,4-Di-N-Oxides against Escherichia coli

(2015) Guyue Cheng et al.   PLoS One

The Polyketide Synthase Pks13 Catalyzes a Novel Mechanism of Lipid Transfer in Mycobacteria

(2014) Sabine Gavalda et al.   CHEMISTRY & BIOLOGY

Trifluoromethyl Ethers and –Thioethers as Tools for Medicinal Chemistry and Drug Discovery

(2014) Gregory Landelle et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Revisiting the Synthesis of 4,6-Difluorobenzofuroxan: A Study of Its Reactivity and Access to Fluorinated Quinoxaline Oxides

(2014) Cyril Jovené et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Acquired Resistance of Mycobacterium tuberculosis to Bedaquiline

(2014) Koen Andries et al.   PLoS One

Novel quinoxaline 1,4-di-N-oxide derivatives as new potential antichagasic agents

(2013) Enrique Torres et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Cyclic Voltammetric Study of Some Anti-Chagas-Active 1,4-Dioxidoquinoxalin-2-yl Ketone Derivatives

(2013) Silvia Pérez-Silanes et al.   HELVETICA CHIMICA ACTA

Anti-Mycobacterium tuberculosis Agents Derived from Quinoxaline-2-carbonitrile and Quinoxaline-2-carbonitrile 1,4-di-N-oxide

(2012) Miguel Ortega et al.   ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH

Primer-BLAST: A tool to design target-specific primers for polymerase chain reaction

(2012) Jian Ye et al.   BMC BIOINFORMATICS

VarScan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing

(2012) D. C. Koboldt et al.   GENOME RESEARCH

A statistical framework for SNP calling, mutation discovery, association mapping and population genetical parameter estimation from sequencing data

(2011) H. Li   BIOINFORMATICS

3-TrifluoromethylquinoxalineN,N′-Dioxides as Anti-Trypanosomatid Agents. Identification of Optimal Anti-T. cruziAgents and Mechanism of Action Studies

(2011) Diego Benitez et al.   JOURNAL OF MEDICINAL CHEMISTRY

Fast and accurate long-read alignment with Burrows–Wheeler transform

(2010) Heng Li et al.   BIOINFORMATICS

Azole resistance in Mycobacterium tuberculosis is mediated by the MmpS5–MmpL5 efflux system

(2008) Anna Milano et al.   TUBERCULOSIS