A combination of pharmacophore modeling, molecular docking, and virtual screening for P2Y12 receptor antagonists from Chinese herbs

Structure of the human P2Y12 receptor in complex with an antithrombotic drug

(2014) Kaihua Zhang et al.   NATURE

Current Oral Antiplatelets: Focus Update on Prasugrel

(2012) J. John et al.   Journal of the American Board of Family Medicine

Anti-platelet therapy: ADP receptor antagonists

(2011) Yanushi Dullewe Wijeyeratne et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Discovery of Potent Competitive Antagonists and Positive Modulators of the P2X2 Receptor

(2011) Younis Baqi et al.   JOURNAL OF MEDICINAL CHEMISTRY

The P2Y12 receptor as a target of antithrombotic drugs

(2011) Stephen O’Connor et al.   Purinergic Signalling

Piperazinyl-glutamate-pyridines as potent orally bioavailable P2Y12 antagonists for inhibition of platelet aggregation

(2009) John J. Parlow et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Thienopyrimidine-based P2Y12 platelet aggregation inhibitors

(2009) Steven W. Kortum et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

High-Affinity, Non-Nucleotide-Derived Competitive Antagonists of Platelet P2Y12Receptors

(2009) Younis Baqi et al.   JOURNAL OF MEDICINAL CHEMISTRY