WASH interacts with Ku to regulate DNA double-stranded break repair

Effects of ER-resident and secreted AGR2 on cell proliferation, migration, invasion, and survival in PANC-1 pancreatic cancer cells

(2021) Xian Hong et al.   BMC CANCER

DNA-PKcs promotes chromatin decondensation to facilitate initiation of the DNA damage response

(2019) Huiming Lu et al.   NUCLEIC ACIDS RESEARCH

R-loops cause genomic instability in T helper lymphocytes from patients with Wiskott-Aldrich syndrome

(2018) Koustav Sarkar et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Super-resolution imaging identifies PARP1 and the Ku complex acting as DNA double-strand break sensors

(2018) Guang Yang et al.   NUCLEIC ACIDS RESEARCH

Nuclear F-actin and myosins drive relocalization of heterochromatic breaks

(2018) Christopher P. Caridi et al.   NATURE

Nuclear ARP2/3 drives DNA break clustering for homology-directed repair

(2018) Benjamin R. Schrank et al.   NATURE

Retriever is a multiprotein complex for retromer-independent endosomal cargo recycling

(2017) Kerrie E. McNally et al.   NATURE CELL BIOLOGY

WASH maintains NKp46+ ILC3 cells by promoting AHR expression

(2017) Pengyan Xia et al.   Nature Communications

Repair Pathway Choices and Consequences at the Double-Strand Break

(2016) Raphael Ceccaldi et al.   TRENDS IN CELL BIOLOGY

Wash Interacts with Lamin and Affects Global Nuclear Organization

(2015) Jeffrey M. Verboon et al.   CURRENT BIOLOGY

The Ku heterodimer: Function in DNA repair and beyond

(2015) Victoria L. Fell et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Organization and dynamics of the nonhomologous end-joining machinery during DNA double-strand break repair

(2015) Dylan A. Reid et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

WASH is required for the differentiation commitment of hematopoietic stem cells in a c-Myc–dependent manner

(2014) Pengyan Xia et al.   JOURNAL OF EXPERIMENTAL MEDICINE

INO80 and SWR complexes: relating structure to function in chromatin remodeling

(2014) Christian B. Gerhold et al.   TRENDS IN CELL BIOLOGY

Chromatin Remodeling at DNA Double-Strand Breaks

(2013) Brendan D. Price et al.   CELL

Regulation of WASH-Dependent Actin Polymerization and Protein Trafficking by Ubiquitination

(2013) Yi-Heng Hao et al.   CELL

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Evidence for monomeric actin function in INO80 chromatin remodeling

(2013) Prabodh Kapoor et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mechanisms of nuclear actin in chromatin-remodeling complexes

(2013) Prabodh Kapoor et al.   TRENDS IN CELL BIOLOGY

Regulation of integrin trafficking, cell adhesion, and cell migration by WASH and the Arp2/3 complex

(2012) Steve N. Duleh et al.   Cytoskeleton

Trafficking defects in WASH-knockout fibroblasts originate from collapsed endosomal and lysosomal networks

(2012) Timothy S. Gomez et al.   MOLECULAR BIOLOGY OF THE CELL

A human XRCC4–XLF complex bridges DNA

(2012) Sara N. Andres et al.   NUCLEIC ACIDS RESEARCH

XRCC4 Protein Interactions with XRCC4-like Factor (XLF) Create an Extended Grooved Scaffold for DNA Ligation and Double Strand Break Repair

(2011) Michal Hammel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural characterization of filaments formed by human Xrcc4-Cernunnos/XLF complex involved in nonhomologous DNA end-joining

(2011) V. Ropars et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamics of the PI3K-like protein kinase members ATM and DNA-PKcs at DNA double strand breaks

(2010) Anthony J. Davis et al.   CELL CYCLE

The complexity of phosphorylated H2AX foci formation and DNA repair assembly at DNA double-strand breaks

(2010) Asako J. Nakamura et al.   CELL CYCLE

WASH and WAVE actin regulators of the Wiskott-Aldrich syndrome protein (WASP) family are controlled by analogous structurally related complexes

(2010) D. Jia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Wash functions downstream of Rho and links linear and branched actin nucleation factors

(2009) R. Liu et al.   DEVELOPMENT

The Arp2/3 Activator WASH Controls the Fission of Endosomes through a Large Multiprotein Complex

(2009) Emmanuel Derivery et al.   DEVELOPMENTAL CELL

A FAM21-Containing WASH Complex Regulates Retromer-Dependent Sorting

(2009) Timothy S. Gomez et al.   DEVELOPMENTAL CELL

ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2

(2009) Andrea Beucher et al.   EMBO JOURNAL

DNA-PK and ATM phosphorylation sites in XLF/Cernunnos are not required for repair of DNA double strand breaks

(2008) Y YU et al.   DNA REPAIR

Comparison of nonhomologous end joining and homologous recombination in human cells

(2008) Z MAO et al.   DNA REPAIR

Alternative-NHEJ Is a Mechanistically Distinct Pathway of Mammalian Chromosome Break Repair

(2008) Nicole Bennardo et al.   PLoS Genetics