p38MAPK Signaling Pathway in Osteoarthritis: Pathological and Therapeutic Aspects
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
p38MAPK Signaling Pathway in Osteoarthritis: Pathological and Therapeutic Aspects
Authors
Keywords
-
Journal
Journal of Inflammation Research
Volume Volume 15, Issue -, Pages 723-734
Publisher
Informa UK Limited
Online
2022-02-02
DOI
10.2147/jir.s348491
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Huanglian Jiedu Decoction Exerts Antipyretic Effect by Inhibiting MAPK Signaling Pathway
- (2022) Xing Li et al. Evidence-based Complementary and Alternative Medicine
- CTRP9 protects against MIA-induced inflammation and knee cartilage damage by deactivating the MAPK/NF-κB pathway in rats with osteoarthritis
- (2021) Shicheng Zheng et al. Open Life Sciences
- Osteoarthritic infrapatellar fat pad aggravates cartilage degradation via activation of p38MAPK and ERK1/2 pathways
- (2021) Zuoqing Zhou et al. INFLAMMATION RESEARCH
- Elevated p38MAPK activity promotes neural stem cell aging
- (2020) Leire Moreno-Cugnon et al. Aging-US
- miR-296-5p inhibits IL-1β-induced apoptosis and cartilage degradation in human chondrocytes by directly targeting TGF-β1/CTGF/p38MAPK pathway
- (2020) Zhilin Cao et al. CELL CYCLE
- Inhibition of p38mapk Reduces Adipose Tissue Inflammation in Aging Mediated by Arginase-II
- (2020) Ji Huang et al. PHARMACOLOGY
- Salvianolic Acid A Exhibits Anti-Inflammatory and Antiarthritic Effects via Inhibiting NF-κB and p38/MAPK Pathways
- (2020) Shuang Feng et al. Drug Design Development and Therapy
- Resistin Enhances VCAM-1 Expression and Monocyte Adhesion in Human Osteoarthritis Synovial Fibroblasts by Inhibiting MiR-381 Expression through the PKC, p38, and JNK Signaling Pathways
- (2020) Wei-Cheng Chen et al. Cells
- An Update on Venous Thromboembolism Rates and Prophylaxis in Hip and Knee Arthroplasty in 2020
- (2020) Daniel C. Santana et al. Medicina-Lithuania
- The Novel p38 Inhibitor, Pamapimod, Inhibits Osteoclastogenesis and Counteracts Estrogen-Dependent Bone Loss in Mice
- (2019) Xiangde Zhao et al. JOURNAL OF BONE AND MINERAL RESEARCH
- A Phase 2 Trial of Lutikizumab, an Anti-Interleukin 1α/β Dual Variable Domain Immunoglobulin, in Knee Osteoarthritis Patients With Synovitis
- (2019) Roy M. Fleischmann et al. Arthritis & Rheumatology
- Mechano growth factor attenuates mechanical overload-induced nucleus pulposus cell apoptosis through inhibiting the p38 MAPK pathway
- (2019) Qing Xu et al. BIOSCIENCE REPORTS
- Osteoarthritis
- (2019) David J Hunter et al. LANCET
- SB203580, a p38MAPK inhibitor, attenuates olfactory dysfunction by inhibiting OSN apoptosis in AR mice (activation and involvement of the p38 mitogen‐activated protein kinase in olfactory sensory neuronal apoptosis of OVA‐induced allergic rhinitis)
- (2019) Xian Gao et al. Brain and Behavior
- Rab7 delays intervertebral disc degeneration through the inhibition of the p38MAPK pathway
- (2019) Xu Chen et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Angiopoietin-like 2 upregulation promotes human chondrocyte injury via NF-κB and p38/MAPK signaling pathway
- (2019) Wenshan Shan et al. JOURNAL OF BONE AND MINERAL METABOLISM
- MicroRNA-125b-5p regulates IL-1β induced inflammatory genes via targeting TRAF6-mediated MAPKs and NF-κB signaling in human osteoarthritic chondrocytes
- (2019) Zafar Rasheed et al. Scientific Reports
- Aging Increases Hippocampal DUSP2 by a Membrane Cholesterol Loss-Mediated RTK/p38MAPK Activation Mechanism
- (2019) Adrián Martín-Segura et al. Frontiers in Neurology
- LncRNA SNHG1 alleviates IL-1β-induced osteoarthritis by inhibiting miR-16-5p-mediated p38 MAPK and NF-κB signaling pathways
- (2019) Jinlai Lei et al. BIOSCIENCE REPORTS
- Astragalus polysaccharide ameliorates lipopolysaccharide-induced cell injury in ATDC5 cells via miR-92a/KLF4 mediation
- (2019) Lei Fan et al. BIOMEDICINE & PHARMACOTHERAPY
- Combined treatment with SB203580 and dexamethasone suppresses non-typeable Haemophilus influenzae-induced Th17 inflammation response in murine allergic asthma
- (2019) Guoqiang Wang et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- The role of matrix metalloproteinases in osteoarthritis pathogenesis: An updated review
- (2019) El-Sayed E. Mehana et al. LIFE SCIENCES
- Protease-activated receptor 2 (PAR-2) antagonist AZ3451 as a novel therapeutic agent for osteoarthritis
- (2019) Xiaojian Huang et al. Aging-US
- Novel cell‐permeable p38‐MAPK inhibitor efficiently prevents porcine islet apoptosis and improves islet graft function
- (2019) Hirofumi Noguchi et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Tetramethylpyrazine alleviates lipopolysaccharide-induced damage in ATDC5 cells via down-regulating MyD88
- (2019) Qiang Li et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- The regulatory mechanism of p38/MAPK in the chondrogenic differentiation from bone marrow mesenchymal stem cells
- (2019) Ning Ma et al. Journal of Orthopaedic Surgery and Research
- Exosomes derived from platelet-rich plasma present a novel potential in alleviating knee osteoarthritis by promoting proliferation and inhibiting apoptosis of chondrocyte via Wnt/β-catenin signaling pathway
- (2019) Xuchang Liu et al. Journal of Orthopaedic Surgery and Research
- Effects of Notch/p38MAPK signaling pathway on articular cartilage defect recovery by BMSCs tissue based on the rabbit articular cartilage defect models
- (2019) Hui Zhang et al. SAUDI JOURNAL OF BIOLOGICAL SCIENCES
- Advanced oxidation protein products increase TNF-α and IL-1β expression in chondrocytes via NADPH oxidase 4 and accelerate cartilage degeneration in osteoarthritis progression
- (2019) Cong-Rui Liao et al. Redox Biology
- Piperine alleviates lipopolysaccharide-induced inflammatory injury by down-regulating microRNA-127 in murine chondrogenic ATDC5 cells
- (2018) Chunfeng Ren et al. BIOMEDICINE & PHARMACOTHERAPY
- Resveratrol Protects Murine Chondrogenic ATDC5 Cells Against LPS-Induced Inflammatory Injury Through Up-Regulating MiR-146b
- (2018) Hui Jin et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Therapeutics in Osteoarthritis Based on an Understanding of Its Molecular Pathogenesis
- (2018) Ju-Ryoung Kim et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Role of p38/MAPKs in Alzheimer’s disease: implications for amyloid beta toxicity targeted therapy
- (2018) Ghazaleh Kheiri et al. REVIEWS IN THE NEUROSCIENCES
- Metabolic benefits of inhibition of p38α in white adipose tissue in obesity
- (2018) Shengjie Zhang et al. PLOS BIOLOGY
- Pro-inflammatory cytokines: The link between obesity and osteoarthritis
- (2018) Tiantian Wang et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017
- (2018) Spencer L James et al. LANCET
- Osteoarthritis year in review 2018: biology
- (2018) J. Sherwood OSTEOARTHRITIS AND CARTILAGE
- Novel selective TOPK inhibitor SKLB-C05 inhibits colorectal carcinoma growth and metastasis
- (2018) Tiantao Gao et al. CANCER LETTERS
- Recent Advances in the Inhibition of p38 MAPK as a Potential Strategy for the Treatment of Alzheimer’s Disease
- (2017) Jong Kil Lee et al. MOLECULES
- p38MAPK family isoform p38α and activating transcription factor 2 are associated with the malignant phenotypes and poor prognosis of patients with ovarian adenocarcinoma
- (2017) Wan-Juan Song et al. PATHOLOGY RESEARCH AND PRACTICE
- Cancer suppression by systemic inactivation of p38MAPK
- (2017) Anna Brichkina et al. Oncotarget
- The role of resolvin D1 in the regulation of inflammatory and catabolic mediators in osteoarthritis
- (2016) Houda Benabdoune et al. INFLAMMATION RESEARCH
- Explore the variation of MMP3, JNK, p38 MAPKs, and autophagy at the early stage of osteoarthritis
- (2016) Jie Shi et al. IUBMB LIFE
- Hippocampal metabotropic glutamate receptor long-term depression in health and disease: focus on mitogen-activated protein kinase pathways
- (2016) Thomas M. Sanderson et al. JOURNAL OF NEUROCHEMISTRY
- Inhibition of senescence and promotion of the proliferation of chondrocytes from articular cartilage by CsA and FK506 involves inhibition of p38MAPK
- (2016) Seok-Won Kang et al. MECHANISMS OF AGEING AND DEVELOPMENT
- The effect of RO3201195 and a pyrazolyl ketone P38 MAPK inhibitor library on the proliferation of Werner syndrome cells
- (2016) Mark C. Bagley et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- The p38 MAPK inhibitor, SB203580, inhibits cell invasion by Neospora caninum
- (2016) Xiaoxia Jin et al. PARASITOLOGY RESEARCH
- Extracellular Release of Annexin A2 is Enhanced upon Oxidative Stress Response via the p38 MAPK Pathway after Low-Dose X-Ray Irradiation
- (2016) Kazuko Kita et al. RADIATION RESEARCH
- Inhibition of myocyte-specific enhancer factor 2A improved diabetic cardiac fibrosis partially by regulating endothelial-to-mesenchymal transition
- (2016) Xue-ying Chen et al. Oncotarget
- Osteoarthritis
- (2015) S Glyn-Jones et al. LANCET
- NLRP3 inflammasome and its inhibitors: a review
- (2015) Bo-Zong Shao et al. Frontiers in Pharmacology
- F-Box Only Protein 31 (FBXO31) Negatively Regulates p38 Mitogen-activated Protein Kinase (MAPK) Signaling by Mediating Lysine 48-linked Ubiquitination and Degradation of Mitogen-activated Protein Kinase Kinase 6 (MKK6)
- (2014) Jia Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Role of Inflammatory and Anti-Inflammatory Cytokines in the Pathogenesis of Osteoarthritis
- (2014) Piotr Wojdasiewicz et al. MEDIATORS OF INFLAMMATION
- OARSI guidelines for the non-surgical management of knee osteoarthritis
- (2014) T.E. McAlindon et al. OSTEOARTHRITIS AND CARTILAGE
- Amelioration of lesions associated with 24-hour suboptimal platelet storage at 16 °C by a p38MAPK inhibitor, VX-702
- (2014) S. J. Wagner et al. VOX SANGUINIS
- Inhibition of p38 MAPK During Ischemia, But Not Reperfusion, Effectively Attenuates Fatal Arrhythmia in Ischemia/Reperfusion Heart
- (2012) Sirirat Surinkaew et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- ATDC5: An excellent in vitro model cell line for skeletal development
- (2012) Yongchang Yao et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Inhibition of the p38 MAPK pathway ameliorates renal fibrosis in an NPHP2 mouse model
- (2011) Noriyuki Sugiyama et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Disease Modifying Osteoarthritis Drugs: Facing Development Challenges and Choosing Molecular Targets
- (2010) Marie-Pierre Hellio Le Graverand-Gastineau CURRENT DRUG TARGETS
- The role of synovitis in pathophysiology and clinical symptoms of osteoarthritis
- (2010) Jérémie Sellam et al. Nature Reviews Rheumatology
- Role of proinflammatory cytokines in the pathophysiology of osteoarthritis
- (2010) Mohit Kapoor et al. Nature Reviews Rheumatology
- Efficacy, pharmacodynamics, and safety of VX-702, a novel p38 MAPK inhibitor, in rheumatoid arthritis: Results of two randomized, double-blind, placebo-controlled clinical studies
- (2009) Nemanja Damjanov et al. ARTHRITIS AND RHEUMATISM
- Improvement of Canine Islet Yield by Donor Pancreas Infusion With a p38MAPK Inhibitor
- (2009) Taihei Ito et al. TRANSPLANTATION
- Pamapimod, a Novel p38 Mitogen-Activated Protein Kinase Inhibitor: Preclinical Analysis of Efficacy and Selectivity
- (2008) R. J. Hill et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Gene Regulation by Transcription Factors and MicroRNAs
- (2008) O. Hobert SCIENCE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started