Polarization of tumor-associated macrophages by TLR7/8 conjugated radiosensitive peptide hydrogel for overcoming tumor radioresistance

In Situ Supramolecular Self‐Assembly of Pt(IV) Prodrug to Conquer Cisplatin Resistance

(2021) Qian Wang et al.   ADVANCED FUNCTIONAL MATERIALS

Radiotherapy is associated with a deletion signature that contributes to poor outcomes in patients with cancer

(2021) Emre Kocakavuk et al.   NATURE GENETICS

Reversal of the immunosuppressive tumor microenvironment by nanoparticle-based activation of immune-associated cells

(2020) Fei-long Qi et al.   ACTA PHARMACOLOGICA SINICA

Functional Gadofullerene Nanoparticles Trigger Robust Cancer Immunotherapy Based on Rebuilding an Immunosuppressive Tumor Microenvironment

(2020) Lei Li et al.   NANO LETTERS

Development of injectable thermosensitive polypeptide hydrogel as facile radioisotope and radiosensitizer hotspot for synergistic brachytherapy

(2020) Jinjian Liu et al.   Acta Biomaterialia

Nanoscale Metal–Organic Framework Co-delivers TLR-7 Agonists and Anti-CD47 Antibodies to Modulate Macrophages and Orchestrate Cancer Immunotherapy

(2020) Kaiyuan Ni et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Purine metabolism regulates DNA repair and therapy resistance in glioblastoma

(2020) Weihua Zhou et al.   Nature Communications

Re-education of the Tumor Microenvironment With Targeted Therapies and Immunotherapies

(2020) Shin Foong Ngiow et al.   Frontiers in Immunology

M2-Like Tumor-Associated Macrophage-Targeted Codelivery of STAT6 Inhibitor and IKKβ siRNA Induces M2-to-M1 Repolarization for Cancer Immunotherapy with Low Immune Side Effects

(2020) Hong Xiao et al.   ACS Central Science

Bioinspired Nanofibrous Glycopeptide Hydrogel Dressing for Accelerating Wound Healing: A Cytokine‐Free, M2‐Type Macrophage Polarization Approach

(2020) Zujian Feng et al.   ADVANCED FUNCTIONAL MATERIALS

Activating Macrophage‐Mediated Cancer Immunotherapy by Genetically Edited Nanoparticles

(2020) Lang Rao et al.   ADVANCED MATERIALS

Radioresistance in Glioblastoma and the Development of Radiosensitizers

(2020) Md Yousuf Ali et al.   Cancers

The immunological consequences of radiation-induced DNA damage

(2019) Anna C Wilkins et al.   JOURNAL OF PATHOLOGY

Synergetic Functional Nanocomposites Enhance Immunotherapy in Solid Tumors by Remodeling the Immunoenvironment

(2019) Linnan Yang et al.   Advanced Science

Ionizing radiation effects on the tumor microenvironment

(2019) Luigi Portella et al.   SEMINARS IN ONCOLOGY

A toll-like receptor agonist mimicking microbial signal to generate tumor-suppressive macrophages

(2019) Yanxian Feng et al.   Nature Communications

IL-6 induced M1 type macrophage polarization increases radiosensitivity in HPV positive head and neck cancer

(2019) Xiaohang Chen et al.   CANCER LETTERS

DNA damage enhancement by radiotherapy-activated hafnium oxide nanoparticles improves cGAS-STING pathway activation in human colorectal cancer cells

(2019) Julie Marill et al.   RADIOTHERAPY AND ONCOLOGY

mTOR-Mediated Antioxidant Activation in Solid Tumor Radioresistance

(2019) Yunseo Woo et al.   Journal of Oncology

Targeted radiotherapy for early breast cancer

(2018) Jayant S Vaidya et al.   LANCET

Cancer: Re-educating tumour-associated macrophages with nanoparticles

(2018) Megan Cully   NATURE REVIEWS DRUG DISCOVERY

TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy

(2018) Christopher B. Rodell et al.   Nature Biomedical Engineering

The Reciprocity between Radiotherapy and Cancer Immunotherapy

(2018) Yifan Wang et al.   CLINICAL CANCER RESEARCH

Tumour-associated macrophages as treatment targets in oncology

(2017) Alberto Mantovani et al.   Nature Reviews Clinical Oncology

Smac mimetics and oncolytic viruses synergize in driving anticancer T-cell responses through complementary mechanisms

(2017) Dae-Sun Kim et al.   Nature Communications

M2 macrophages are more resistant than M1 macrophages following radiation therapy in the context of glioblastoma

(2017) Marine M. Leblond et al.   Oncotarget

Reprogramming of Tumor-Associated Macrophages with Anticancer Therapies: Radiotherapy versus Chemo- and Immunotherapies

(2017) Géraldine Genard et al.   Frontiers in Immunology

Interaction between Treg cells and tumor-associated macrophages in the tumor microenvironment of epithelial ovarian cancer

(2016) Qinyi Zhu et al.   ONCOLOGY REPORTS

Smac Therapeutic Peptide Nanoparticles Inducing Apoptosis of Cancer Cells for Combination Chemotherapy with Doxorubicin

(2015) Mingxing Li et al.   ACS Applied Materials & Interfaces

The effect of ionizing radiation on regulatory T cells in health and disease

(2015) Eszter Persa et al.   CANCER LETTERS

Promises and Challenges of Smac Mimetics as Cancer Therapeutics

(2015) S. Fulda   CLINICAL CANCER RESEARCH

CDKN1A regulates Langerhans cell survival and promotes Treg cell generation upon exposure to ionizing irradiation

(2015) Jeremy G Price et al.   NATURE IMMUNOLOGY