Gene and virotherapy for hematological malignancies

513. Armed-Ad Gene Therapy Expressing PD-L1 Minibody Enhances the Anti-Tumor Effect of Adoptively Transferred Chimeric Antigen Receptor T-Cells for Solid Tumor Treatment

(2016) Amanda Rosewell Shaw et al.   MOLECULAR THERAPY

515. Oncolytic Adenovirus Armed with Cytokines Enhances CAR-T Cell Efficacy in Pancreatic Tumor Model

(2016) Keisuke Watanabe et al.   MOLECULAR THERAPY

Transcriptional gene silencing in humans

(2016) Marc S. Weinberg et al.   NUCLEIC ACIDS RESEARCH

Toll-like receptor-5 agonist, entolimod, suppresses metastasis and induces immunity by stimulating an NK-dendritic-CD8+T-cell axis

(2016) Craig M. Brackett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Talimogene Laherparepvec Improves Durable Response Rate in Patients With Advanced Melanoma

(2015) Robert H.I. Andtbacka et al.   JOURNAL OF CLINICAL ONCOLOGY

Harnessing RNAi-based nanomedicines for therapeutic gene silencing in B-cell malignancies

(2015) Shiri Weinstein et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Measles Edmonston vaccine strain derivatives have potent oncolytic activity against osteosarcoma

(2014) E Domingo-Musibay et al.   CANCER GENE THERAPY

Paradoxical Decrease in the Capture and Lymph Node Delivery of Cancer Vaccine Antigen Induced by a TLR4 Agonist as Visualized by Dual-Mode Imaging

(2014) D. K. Kadayakkara et al.   CANCER RESEARCH

RNAi-mediated silencing of MLL-AF9 reveals leukemia-associated downstream targets and processes

(2014) Katrin K Fleischmann et al.   Molecular Cancer

Reovirus as a successful ex vivo purging modality for multiple myeloma

(2013) C M Thirukkumaran et al.   BONE MARROW TRANSPLANTATION

Leukemia Cell-Rhabdovirus Vaccine: Personalized Immunotherapy for Acute Lymphoblastic Leukemia

(2013) D. P. Conrad et al.   CLINICAL CANCER RESEARCH

Oncolytic measles virus strains as novel anticancer agents

(2013) Pavlos Msaouel et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Oncolytic myxoma virus: The path to clinic

(2013) Winnie M. Chan et al.   VACCINE

Non-replicating rhabdovirus-derived particles (NRRPs) eradicate acute leukemia by direct cytolysis and induction of antitumor immunity

(2013) C Batenchuk et al.   Blood Cancer Journal

Selective Purging of Human Multiple Myeloma Cells from Autologous Stem Cell Transplantation Grafts using Oncolytic Myxoma Virus

(2012) Eric Bartee et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Sindbis viral vectors target hematopoietic malignant cells

(2012) R Suzme et al.   CANCER GENE THERAPY

Infectivity-selective Oncolytic Adenovirus Developed by High-throughput Screening of Adenovirus-formatted Library

(2012) Yoshiaki Miura et al.   MOLECULAR THERAPY

A transgene-encoded cell surface polypeptide for selection, in vivo tracking, and ablation of engineered cells

(2011) X. Wang et al.   BLOOD

Considerations for the Clinical Application of Chimeric Antigen Receptor T Cells: Observations from a Recombinant DNA Advisory Committee Symposium Held June 15, 2010

(2011) H. C. J. Ertl et al.   CANCER RESEARCH

Inducible Apoptosis as a Safety Switch for Adoptive Cell Therapy

(2011) Antonio Di Stasi et al.   NEW ENGLAND JOURNAL OF MEDICINE

In vivo depletion of T lymphocyte-specific transcription factors by RNA interference

(2010) Antoine Tesniere et al.   CELL CYCLE

K562/GM-CSF Immunotherapy Reduces Tumor Burden in Chronic Myeloid Leukemia Patients with Residual Disease on Imatinib Mesylate

(2010) B. D. Smith et al.   CLINICAL CANCER RESEARCH

Oncolytic viral purging of leukemic hematopoietic stem and progenitor cells with Myxoma virus

(2010) Masmudur M. Rahman et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Use of attenuated paramyxoviruses for cancer therapy

(2010) Patrycja J Lech et al.   Expert Review of Vaccines

Suicide gene therapy for graft-versus-host disease

(2010) Anna-Maria Georgoudaki et al.   Immunotherapy

A novel in vivo siRNA delivery system specifically targeting dendritic cells and silencing CD40 genes for immunomodulation

(2009) X. Zheng et al.   BLOOD

Infusion of suicide-gene-engineered donor lymphocytes after family haploidentical haemopoietic stem-cell transplantation for leukaemia (the TK007 trial): a non-randomised phase I–II study

(2009) Fabio Ciceri et al.   LANCET ONCOLOGY

Myxoma virus targets primary human leukemic stem and progenitor cells while sparing normal hematopoietic stem and progenitor cells

(2009) M Kim et al.   LEUKEMIA

Transcription factors down-stream of Ras as molecular indicators for targeting malignancies with oncolytic herpes virus

(2009) Tuba Esfandyari et al.   Molecular Oncology

Impaired interferon signaling is a common immune defect in human cancer

(2009) R. J. Critchley-Thorne et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Resolution of liver cirrhosis using vitamin A–coupled liposomes to deliver siRNA against a collagen-specific chaperone

(2008) Yasushi Sato et al.   NATURE BIOTECHNOLOGY