Synthesis, Characterization, Crystal Structure, DNA and HSA Interactions, and Anticancer Activity of a Mononuclear Cu(II) Complex with a Schiff Base Ligand Containing a Thiadiazoline Moiety

Synthesis, characterization, crystal structure, DNA and human serum albumin interactions, as well as antiproliferative activity of a Cu(II) complex containing a Schiff base ligand formed in situ from the Cu(II)‐induced cyclization of 1,5‐bis(salicylidene)thiocarbohydrazide

(2021) Sidhali U. Parsekar et al.   APPLIED ORGANOMETALLIC CHEMISTRY

Probing the Interaction between Human Serum Albumin and 9-Hydroxyphenanthrene: A Spectroscopic and Molecular Docking Study

(2020) Jing Zhang et al.   ACS Omega

Copper(II) Complexes with Mixed Heterocycle Ligands as Promising Antibacterial and Antitumor Species

(2020) Arpad Mihai Rostas et al.   MOLECULES

Copper Complexes as Anticancer Agents Targeting Topoisomerases I and II

(2020) Caroline Molinaro et al.   Cancers

In vitro and in vivo antitumor activities of three novel binuclear platinum(II) complexes with 4′-substituted-2,2′:6′,2″-terpyridine ligands

(2019) Qi-Pin Qin et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Insight of the Interaction between 2,4-thiazolidinedione and Human Serum Albumin: A Spectroscopic, Thermodynamic and Molecular Docking Study

(2019) Safikur Rahman et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Towards the functional high-resolution coordination chemistry of blood plasma human serum albumin

(2019) Samah Al-Harthi et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Cycloplatinated(II) Derivatives of Mercaptopurine Capable of Binding Interactions with HSA/DNA

(2019) Marzieh Dadkhah Aseman et al.   INORGANIC CHEMISTRY

DNA binding and cytotoxicity of two Cu(II) complexes containing a Schiff base ligand along with 1,10-phenanthroline or imidazole as a coligand

(2018) Manjuri K. Koley et al.   INORGANICA CHIMICA ACTA

Human serum albumin interaction studies of a new copper(II) complex containing ceftobiprole drug using molecular modeling and multispectroscopic methods

(2018) Nahid Shahabadi et al.   JOURNAL OF COORDINATION CHEMISTRY

Harnessing albumin as a carrier for cancer therapies

(2018) Ella N. Hoogenboezem et al.   ADVANCED DRUG DELIVERY REVIEWS

Copper(ii) complexes based on quinoline-derived Schiff-base ligands: synthesis, characterization, HSA/DNA binding ability, and anticancer activity

(2018) Kun Hu et al.   MedChemComm

Cytotoxicity studies, DNA interaction and protein binding of new Al (III), Ga (III) and In (III) complexes with 5-hydroxyflavone

(2018) Alexandra-Cristina Munteanu et al.   APPLIED ORGANOMETALLIC CHEMISTRY

Stimuli-Responsive Therapeutic Metallodrugs

(2018) Xiaohui Wang et al.   CHEMICAL REVIEWS

DNA binding and cytotoxicity of some Cu(II)/Zn(II) complexes containing a carbohydrazone Schiff base ligand along with 1,10-phenanthroline as a coligand

(2017) Manjuri K. Koley et al.   INORGANICA CHIMICA ACTA

Two Cu(II) complexes containing 2,4-diamino-6-(2-pyridyl)-1,3,5-triazine and amino acids: Synthesis, crystal structures, DNA/HSA binding, molecular docking, and in vitro cytotoxicity studies

(2017) Fang Shen et al.   INORGANICA CHIMICA ACTA

Synthesis, crystal structures, molecular docking and in vitro cytotoxicity studies of two new copper(ii) complexes: special emphasis on their binding to HSA

(2017) Fang Shen et al.   NEW JOURNAL OF CHEMISTRY

Biological evaluation of dinuclear copper complex/dichloroacetic acid cocrystal against human breast cancer: design, synthesis, characterization, DFT studies and cytotoxicity assays

(2017) Mohammad Usman et al.   RSC Advances

Tert-butyl hydroperoxide (t-BHP) induced apoptosis and necroptosis in endothelial cells: Roles of NOX4 and mitochondrion

(2017) Wenwen Zhao et al.   Redox Biology

The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs

(2016) Timothy C. Johnstone et al.   CHEMICAL REVIEWS

Copper complexes based on chiral Schiff-base ligands: DNA/BSA binding ability, DNA cleavage activity, cytotoxicity and mechanism of apoptosis

(2016) Xue-Quan Zhou et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Biological evaluation of dimethylpyridine–platinum complexes with potent antiproliferative activity

(2016) Robert Czarnomysy et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

X-ray Structure Analysis of Indazolium trans-[Tetrachlorobis(1H-indazole)ruthenate(III)] (KP1019) Bound to Human Serum Albumin Reveals Two Ruthenium Binding Sites and Provides Insights into the Drug Binding Mechanism

(2016) Aleksandar Bijelic et al.   JOURNAL OF MEDICINAL CHEMISTRY

Developing an Anticancer Copper(II) Pro-Drug Based on the His242 Residue of the Human Serum Albumin Carrier IIA Subdomain

(2016) Jinxu Qi et al.   MOLECULAR PHARMACEUTICS

Catecholase activity, DNA binding and cytotoxicity studies of a Cu(ii) complex of a pyridoxal schiff base: synthesis, X-ray crystal structure, spectroscopic, electrochemical and theoretical studies

(2016) Piyali Adak et al.   RSC Advances

A mononuclear Cu(II) complex with 5,6-diphenyl-3-(2-pyridyl)-1,2,4-triazine: Synthesis, crystal structure, DNA- and BSA-binding, molecular modeling, and anticancer activity against MCF-7, A-549, and HT-29 cell lines

(2015) Marzieh Anjomshoa et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Antiangiogenic Activity of Mononuclear Copper(II) Polypyridyl Complexes for the Treatment of Cancers

(2015) Penumaka Nagababu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Comparative Cytotoxicity of Artemisinin and Cisplatin and Their Interactions with Chlorogenic Acids in MCF7 Breast Cancer Cells

(2014) John O. Suberu et al.   ChemMedChem

DNA/protein interaction and cytotoxic activity of imidazole terpyridine derived Cu(ii)/Zn(ii) metal complexes

(2014) V. M. Manikandamathavan et al.   DALTON TRANSACTIONS

DNA condensation by copper(II) complexes and their anti-proliferative effect on cancerous and normal fibroblast cells

(2014) Subramaniyam Rajalakshmi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Interaction of the anticancer gallium(III) complexes of 8-hydroxyquinoline and maltol with human serum proteins

(2014) Éva A. Enyedy et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Two water-soluble copper(II) complexes: Synthesis, characterization, DNA cleavage, protein binding activities and in vitro anticancer activity studies

(2014) Jing Lu et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Interaction of human serum albumin with sulfadiazine

(2014) Mohd Sajid Ali et al.   JOURNAL OF MOLECULAR LIQUIDS

ROS-Mediated Cytotoxic Effect of Copper(II) Hydrazone Complexes against Human Glioma Cells

(2014) Angel Recio Despaigne et al.   MOLECULES

Advances in Copper Complexes as Anticancer Agents

(2013) Carlo Santini et al.   CHEMICAL REVIEWS

DNA-binding of nickel(II), copper(II) and zinc(II) complexes: Structure–affinity relationships

(2013) Giampaolo Barone et al.   COORDINATION CHEMISTRY REVIEWS

Potential cytotoxic and amoebicide activity of first row transition metal compounds with 2,9-bis-(2′,5′-diazahexanyl)-1,1-phenanthroline (L1)

(2012) Juan Carlos García-Ramos et al.   DALTON TRANSACTIONS

DNA targeting polyaza macrobicyclic dizinc(ii) complexes promoting high in vitro caspase dependent anti-proliferative activity against human carcinoma cancer cells

(2012) Sellamuthu Anbu et al.   DALTON TRANSACTIONS

Affinity of Two Novel Five-Coordinated Anticancer Pt(II) Complexes to Human and Bovine Serum Albumins: A Spectroscopic Approach

(2012) Fayezeh Samari et al.   INORGANIC CHEMISTRY

Characterization of the binding sites of the anticancer ruthenium(III) complexes KP1019 and KP1339 on human serum albumin via competition studies

(2012) Orsolya Dömötör et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Copper(II) complexes of terpyridine derivatives: A footstep towards development of antiproliferative agent for breast cancer

(2012) Subramaniyam Rajalakshmi et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

X-ray Absorption Spectroscopy of an Investigational Anticancer Gallium(III) Drug: Interaction with Serum Proteins, Elemental Distribution Pattern, and Coordination of the Compound in Tissue

(2012) Alfred A. Hummer et al.   JOURNAL OF MEDICINAL CHEMISTRY

Copper(II) Complexes of Salicylic Acid Combining Superoxide Dismutase Mimetic Properties with DNA Binding and Cleaving Capabilities Display Promising Chemotherapeutic Potential with Fast Acting in Vitro Cytotoxicity against Cisplatin Sensitive and Resistant Cancer Cell Lines

(2012) Mark O’Connor et al.   JOURNAL OF MEDICINAL CHEMISTRY

Evaluation of drug–human serum albumin binding interactions with support vector machine aided online automated docking

(2011) Ferenc Zsila et al.   BIOINFORMATICS

Copper(II), zinc(II) and nickel(II) complexes as nuclease mimetics

(2011) Dominique Desbouis et al.   COORDINATION CHEMISTRY REVIEWS

Effect of terminal N-substitution in 2-oxo-1,2-dihydroquinoline-3-carbaldehyde thiosemicarbazones on the mode of coordination, structure, interaction with protein, radical scavenging and cytotoxic activity of copper(ii) complexes

(2011) Duraisamy Senthil Raja et al.   DALTON TRANSACTIONS

Ferrocene-Conjugatedl-Tryptophan Copper(II) Complexes of Phenanthroline Bases Showing DNA Photocleavage Activity and Cytotoxicity

(2011) Tridib K. Goswami et al.   INORGANIC CHEMISTRY

The Crystal Structure and Cytotoxicity of Centrosymmetric Copper(II) Complex Derived from S-methyldithiocarbazate with Isatin

(2011) Mohd Abdul Fatah Abdul Manan et al.   JOURNAL OF CHEMICAL CRYSTALLOGRAPHY

Remarkable photocytotoxicity in hypoxic HeLa cells by a dipyridophenazine copper(II) Schiff base thiolate

(2011) Debojyoti Lahiri et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Study on potential antitumor mechanism of a novel Schiff Base copper(II) complex: Synthesis, crystal structure, DNA binding, cytotoxicity and apoptosis induction activity

(2011) Xin Qiao et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Copper Binding Agents Acting as Copper Ionophores Lead to Caspase Inhibition and Paraptotic Cell Death in Human Cancer Cells

(2011) Saverio Tardito et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mononuclear copper(II) complex with terpyridine and an extended phenanthroline base, [Cu(tpy)(dppz)]2+: Synthesis, crystal structure, DNA binding and cytotoxicity activity

(2011) Khatereh Abdi et al.   POLYHEDRON

An effective approach to artificial nucleases using copper(ii) complexes bearing nucleobases

(2010) Jin-Tao Wang et al.   DALTON TRANSACTIONS

The status of platinum anticancer drugs in the clinic and in clinical trials

(2010) Nial J. Wheate et al.   DALTON TRANSACTIONS

Synthesis, characterization antibacterial and antiproliferative activity of novel Cu(II) and Pd(II) complexes with 2-hydroxy-8-R-tricyclo[7.3.1.0.2,7]tridecane-13-one thiosemicarbazone

(2009) Tudor Rosu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Mixed-Ligand Copper(II) Maltolate Complexes: Synthesis, Characterization, DNA Binding and Cleavage, and Cytotoxicity

(2009) Archika Barve et al.   INORGANIC CHEMISTRY

Anticancer activity, structure, and theoretical calculation of N-(1-phenyl-3-methyl-4-propyl-pyrazolone-5)-salicylidene hydrazone and its copper(II) complex

(2009) Yanhui Zhang et al.   INORGANICA CHIMICA ACTA

Inhibition of transcription by platinum antitumor compounds

(2009) Ryan C. Todd et al.   Metallomics

The effect of MG132, a proteasome inhibitor on HeLa cells in relation to cell growth, reactive oxygen species and GSH

(2009) Park   ONCOLOGY REPORTS