The Association between TNF-α, IL-6, and Vitamin D Levels and COVID-19 Severity and Mortality: A Systematic Review and Meta-Analysis
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Title
The Association between TNF-α, IL-6, and Vitamin D Levels and COVID-19 Severity and Mortality: A Systematic Review and Meta-Analysis
Authors
Keywords
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Journal
Pathogens
Volume 11, Issue 2, Pages 195
Publisher
MDPI AG
Online
2022-02-02
DOI
10.3390/pathogens11020195
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Note: Only part of the references are listed.- Exploring the link between Vitamin D and clinical outcomes in COVID-19.
- (2021) Prateek Lohia et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Inflammation‐associated factors for predicting in‐hospital mortality in patients with COVID‐19
- (2021) Jun‐Hong Wang et al. JOURNAL OF MEDICAL VIROLOGY
- Vitamin D Deficiency and Low Serum Calcium as Predictors of Poor Prognosis in Patients with Severe COVID-19
- (2021) Salam Bennouar et al. JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION
- Elevated plasma IL-6 and CRP levels are associated with adverse clinical outcomes and death in critically ill SARS-CoV-2 patients: inflammatory response of SARS-CoV-2 patients
- (2021) Jean-Rémi Lavillegrand et al. Annals of Intensive Care
- Hyperosmolarity Deserves More Attention in Critically Ill COVID-19 Patients with Diabetes: A Cohort-Based Study
- (2021) Luoning Gou et al. Diabetes Metabolic Syndrome and Obesity-Targets and Therapy
- Baseline characteristics and changes of biomarkers in disease course predict prognosis of patients with COVID-19
- (2021) Tao Li et al. Internal and Emergency Medicine
- The role of IL-6/lymphocyte ratio in the peripheral blood of severe patients with COVID-19
- (2021) Boyi Yang et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- The association between micronutrient and hemogram values and prognostic factors in COVID‐19 patients: A single‐center experience from Turkey
- (2021) Ayşegül Ersöz et al. INTERNATIONAL JOURNAL OF CLINICAL PRACTICE
- The Inflammatory Factors Associated with Disease Severity to Predict COVID-19 Progression
- (2021) Wei Huang et al. JOURNAL OF IMMUNOLOGY
- Association of Vitamin D Status with SARS-CoV-2 Infection or COVID-19 Severity: A Systematic Review and Meta-analysis
- (2021) Asma Kazemi et al. Advances in Nutrition
- Peripheral Inflammatory Cytokines and Lymphocyte Subset Features of Deceased COVID-19 Patients
- (2021) Nan Jiang et al. Biomed Research International
- Association and Interaction Between Serum Interleukin-6 Levels and Metabolic Dysfunction-Associated Fatty Liver Disease in Patients With Severe Coronavirus Disease 2019
- (2021) Feng Gao et al. Frontiers in Endocrinology
- Implications of Laboratory Tests in Disease Grading and Death Risk Stratification of COVID-19: A Retrospective Study in Wuhan, China
- (2021) Yang Bai et al. Frontiers in Medicine
- Clinical characteristics and risk factors for mortality in patients with coronavirus disease 2019 in intensive care unit: a single- center, retrospective, observational study in China
- (2021) Fangfang Sai et al. Annals of Palliative Medicine
- The Leading Causes of Death in the US for 2020
- (2021) Farida B. Ahmad et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Analysis of cytokines in SARS-CoV-2 or COVID-19 patients in Erbil city, Kurdistan Region of Iraq
- (2021) Mohammed Yousif Merza et al. PLoS One
- COVID-19 Disease Severity and Death in Relation to Vitamin D Status among SARS-CoV-2-Positive UAE Residents
- (2021) Habiba AlSafar et al. Nutrients
- Lack of association of baseline 25-hydroxyvitamin D levels with disease severity and mortality in Indian patients hospitalized for COVID-19
- (2021) Ganesh Jevalikar et al. Scientific Reports
- PaO2/FiO2 and IL-6 are risk factors of mortality for intensive care COVID-19 patients
- (2021) Yanli Gu et al. Scientific Reports
- Vitamin D and COVID-19 severity and related mortality: a prospective study in Italy
- (2021) Irene Campi et al. BMC INFECTIOUS DISEASES
- Serum IL-6: A potential biomarker of mortality among SARS-CoV-2 infected patients in Mexico
- (2021) Azalia Avila-Nava et al. CYTOKINE
- Prognostic parameters of in‐hospital mortality in COVID‐19 patients—An Italian experience
- (2021) Massimiliano Ruscica et al. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
- Immunological predictors of disease severity in patients with COVID-19
- (2021) Asma Al Balushi et al. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
- Low serum level of apolipoprotein A1 may predict the severity of COVID‐19: A retrospective study
- (2021) Zhe Zhu et al. JOURNAL OF CLINICAL LABORATORY ANALYSIS
- The relationship between 25(OH) vitamin D levels and COVID-19 onset and disease course in Spanish patients
- (2021) Manuel Diaz-Curiel et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Serum IL-6 and procalcitonin are two promising novel biomarkers for evaluating the severity of COVID-19 patients
- (2021) Jinsong Tang et al. MEDICINE
- Viral loads, lymphocyte subsets and cytokines in asymptomatic, mildly and critical symptomatic patients with SARS-CoV-2 infection: a retrospective study
- (2021) Shi-Wei Yin et al. Virology Journal
- Association of Clinical and Immunological Characteristics With Disease Severity and Outcomes in 211 Patients With COVID-19 in Wuhan, China
- (2021) Man Wang et al. Frontiers in Cellular and Infection Microbiology
- Analysis of Lymphocyte Subpopulations and Cytokines in COVID-19-Associated Pneumonia and Community-Acquired Pneumonia
- (2021) Guohong Liu et al. Journal of Immunology Research
- The predictive power of serum vitamin D for poor outcomes in COVID‐19 patients
- (2021) Hoda Derakhshanian et al. Food Science & Nutrition
- Efficacy and safety of IL-6 inhibitors in patients with COVID-19 pneumonia: a systematic review and meta-analysis of multicentre, randomized trials
- (2021) Alessandro Belletti et al. Annals of Intensive Care
- Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China
- (2020) Zunyou Wu et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
- (2020) Chaolin Huang et al. LANCET
- Using IL‐2R/lymphocytes for predicting the clinical progression of patients with COVID‐19
- (2020) H. Hou et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Dysregulation of Immune Response in Patients With Coronavirus 2019 (COVID-19) in Wuhan, China
- (2020) Chuan Qin et al. CLINICAL INFECTIOUS DISEASES
- Clinical and immunological features of severe and moderate coronavirus disease 2019
- (2020) Guang Chen et al. JOURNAL OF CLINICAL INVESTIGATION
- Risk factors for severe COVID-19: Evidence from 167 hospitalized patients in Anhui, China
- (2020) Yuan-Yuan Wei et al. JOURNAL OF INFECTION
- Diagnostic Utility of Clinical Laboratory Data Determinations for Patients with the Severe COVID‐19
- (2020) Yong Gao et al. JOURNAL OF MEDICAL VIROLOGY
- Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study
- (2020) Fei Zhou et al. LANCET
- Clinical characteristics and risk factors associated with COVID-19 disease severity in patients with cancer in Wuhan, China: a multicentre, retrospective, cohort study
- (2020) Jianbo Tian et al. LANCET ONCOLOGY
- Clinical characteristics and co-infections of 354 hospitalized patients with COVID-19 in Wuhan, China: a retrospective cohort study
- (2020) Zhihua Lv et al. MICROBES AND INFECTION
- The Risk of Children Hospitalized With Severe COVID-19 in Wuhan
- (2020) Yanli Wang et al. PEDIATRIC INFECTIOUS DISEASE JOURNAL
- Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease 2019 Pneumonia in Wuhan, China
- (2020) Chaomin Wu et al. JAMA Internal Medicine
- Infection with SARS-CoV-2 causes abnormal laboratory results of multiple organs in patients
- (2020) Ai-Ping Yang et al. Aging-US
- Vitamin D (VD3) antioxidative and anti-inflammatory activities: Peripheral and central effects
- (2020) Luzia Kalyne Almeida Moreira Leal et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Clinical value of immune-inflammatory parameters to assess the severity of coronavirus disease 2019
- (2020) Zhe Zhu et al. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
- Pathophysiology, Transmission, Diagnosis, and Treatment of Coronavirus Disease 2019 (COVID-19)
- (2020) W. Joost Wiersinga et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- IL-6–based mortality risk model for hospitalized patients with COVID-19
- (2020) Rocio Laguna-Goya et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- The Association of Interleukin‐6 value, Interleukin inhibitors and Outcomes of Patients with COVID‐19 in New York City
- (2020) Tetsuro Maeda et al. JOURNAL OF MEDICAL VIROLOGY
- Clinical Characteristics of confirmed and clinically diagnosed patients with 2019 novel coronavirus pneumonia: a single-center, retrospective, case-control study
- (2020) Chunjin Ke et al. MEDICINA CLINICA
- Mortality in COVID-19 patients with acute respiratory distress syndrome and corticosteroids use: a systematic review and meta-analysis
- (2020) Syed Shahzad Hasan et al. Expert Review of Respiratory Medicine
- Cytokine Storm in COVID-19: The Current Evidence and Treatment Strategies
- (2020) Yujun Tang et al. Frontiers in Immunology
- The laboratory tests and host immunity of COVID-19 patients with different severity of illness
- (2020) Feng Wang et al. JCI Insight
- Leucocyte Subsets Effectively Predict the Clinical Outcome of Patients With COVID-19 Pneumonia: A Retrospective Case-Control Study
- (2020) Jiahua Gan et al. Frontiers in Public Health
- Comparative analysis of laboratory indexes of severe and non-severe patients infected with COVID-19
- (2020) Jinfeng Bao et al. CLINICA CHIMICA ACTA
- Deciphering the COVID‐19 cytokine storm: Systematic review and meta‐analysis
- (2020) Rubina Mulchandani et al. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
- Characteristics of immune cells and cytokines in patients with coronavirus disease 2019 in Guangzhou, China
- (2020) Xing Chen et al. HUMAN IMMUNOLOGY
- Associations between serum amyloid A, interleukin‐6, and COVID‐19: A cross‐sectional study
- (2020) Qian Liu et al. JOURNAL OF CLINICAL LABORATORY ANALYSIS
- Impact of Serum 25(OH) Vitamin D Level on Mortality in Patients with COVID-19 in Turkey
- (2020) S. Karahan et al. Journal of Nutrition Health & Aging
- Does Serum Vitamin D Level Affect COVID-19 Infection and Its Severity?-A Case-Control Study
- (2020) Kun Ye et al. JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION
- An inflammatory cytokine signature predicts COVID-19 severity and survival
- (2020) Diane Marie Del Valle et al. NATURE MEDICINE
- Interleukin‐6 in Covid‐19: A systematic review and meta‐analysis
- (2020) Eric A. Coomes et al. REVIEWS IN MEDICAL VIROLOGY
- Vitamin D Deficiency and Outcome of COVID-19 Patients
- (2020) Aleksandar Radujkovic et al. Nutrients
- Impact of Vitamin D Deficiency on COVID-19—A Prospective Analysis from the CovILD Registry
- (2020) Alex Pizzini et al. Nutrients
- Cytokine storm and COVID-19: a chronicle of pro-inflammatory cytokines
- (2020) Antonella Fara et al. Open Biology
- Exploring links between vitamin D deficiency and COVID-19
- (2020) Mradul Mohan et al. PLoS Pathogens
- Serum Interleukin-6 Concentrations and the Severity of COVID-19 Pneumonia: A Retrospective Study at a Single Center in Bengbu City, Anhui Province, China, in January and February 2020
- (2020) Hong Sun et al. MEDICAL SCIENCE MONITOR
- Selection of an Optimal Combination Panel to Better Triage COVID-19 Hospitalized Patients
- (2020) Yueting Tang et al. Journal of Inflammation Research
- Serum 25(OH)D Level on Hospital Admission Associated With COVID-19 Stage and Mortality
- (2020) Dieter De Smet et al. AMERICAN JOURNAL OF CLINICAL PATHOLOGY
- Risk factors and clinical features of deterioration in COVID-19 patients in Zhejiang, China: a single-centre, retrospective study
- (2020) Ping Yi et al. BMC INFECTIOUS DISEASES
- Predictors of Coronavirus Disease 2019 Severity: A Retrospective Study of 64 Cases
- (2020) Huihuang Huang et al. JAPANESE JOURNAL OF INFECTIOUS DISEASES
- Development and validation of a nomogram using on admission routine laboratory parameters to predict in‐hospital survival of patients with COVID‐19
- (2020) Hao Chen et al. JOURNAL OF MEDICAL VIROLOGY
- Inflammatory-Related Clinical and Metabolic Outcomes in COVID-19 Patients
- (2020) Maria Martinez-Urbistondo et al. MEDIATORS OF INFLAMMATION
- Association of elevated inflammatory markers and severe COVID-19
- (2020) Pan Ji et al. MEDICINE
- High serum IL-6 values increase the risk of mortality and the severity of pneumonia in patients diagnosed with COVID-19
- (2020) Jose J. Guirao et al. MOLECULAR IMMUNOLOGY
- Cytokine Storm May Not Be the Chief Culprit for the Deterioration of COVID-19
- (2020) Yang Gao et al. VIRAL IMMUNOLOGY
- Clinical characteristics and predictors of mortality associated with COVID-19 in elderly patients from a long-term care facility
- (2020) Enrico Maria Trecarichi et al. Scientific Reports
- An immune-based biomarker signature is associated with mortality in COVID-19 patients
- (2020) Michael S. Abers et al. JCI Insight
- Vitamin D 25OH deficiency in COVID-19 patients admitted to a tertiary referral hospital
- (2020) Emanuele Cereda et al. CLINICAL NUTRITION
- The role of vitamin D in increasing circulating T regulatory cell numbers and modulating T regulatory cell phenotypes in patients with inflammatory disease or in healthy volunteers: A systematic review
- (2019) Sheila A. Fisher et al. PLoS One
- The balance of interleukin (IL)-6, IL-6·soluble IL-6 receptor (sIL-6R), and IL-6·sIL-6R·sgp130 complexes allows simultaneous classic and trans-signaling
- (2018) Paul Baran et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The study of vitamin D administration effect on CRP and Interleukin-6 as prognostic biomarkers of ventilator associated pneumonia
- (2018) Amir Ebrahim Miroliaee et al. JOURNAL OF CRITICAL CARE
- Panethnic Differences in Blood Pressure in Europe: A Systematic Review and Meta-Analysis
- (2016) Pietro Amedeo Modesti et al. PLoS One
- TNF biology, pathogenic mechanisms and emerging therapeutic strategies
- (2015) George D. Kalliolias et al. Nature Reviews Rheumatology
- Vitamin D and 1,25(OH)2D Regulation of T cells
- (2015) Margherita Cantorna et al. Nutrients
- Vitamin D Deficiency in Adults: When to Test and How to Treat
- (2010) Kurt A. Kennel et al. MAYO CLINIC PROCEEDINGS
- Serum tumor necrosis factor-alpha concentrations are negatively correlated with serum 25(OH)D concentrations in healthy women
- (2008) Catherine A Peterson et al. Journal of Inflammation-London
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