Mechanosensitive molecular mechanisms of myocardial fibrosis in living myocardial slices

Intact myocardial preparations reveal intrinsic transmural heterogeneity in cardiac mechanics

(2020) Fotios G. Pitoulis et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Long-term functional and structural preservation of precision-cut human myocardium under continuous electromechanical stimulation in vitro

(2019) Carola Fischer et al.   Nature Communications

Myofibroblast Phenotype and Reversibility of Fibrosis in Patients With End-Stage Heart Failure

(2019) Chandan K. Nagaraju et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Biomimetic electromechanical stimulation to maintain adult myocardial slices in vitro

(2019) Samuel A. Watson et al.   Nature Communications

Myocardial slices come to age: an intermediate complexity in vitro cardiac model for translational research

(2019) Fotios G Pitoulis et al.   CARDIOVASCULAR RESEARCH

Mechanical regulation of cardiac fibroblast profibrotic phenotypes

(2017) Kate M. Herum et al.   MOLECULAR BIOLOGY OF THE CELL

IL11 is a crucial determinant of cardiovascular fibrosis

(2017) Sebastian Schafer et al.   NATURE

Preparation of viable adult ventricular myocardial slices from large and small mammals

(2017) Samuel A Watson et al.   Nature Protocols

The Biological Basis for Cardiac Repair After Myocardial Infarction

(2016) Sumanth D. Prabhu et al.   CIRCULATION RESEARCH

Transcriptional control of cardiac fibroblast plasticity

(2016) Janet K. Lighthouse et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Mechanical control of cardiac myofibroblasts

(2016) Sander van Putten et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Matricellular Protein CCN5 Reverses Established Cardiac Fibrosis

(2016) Dongtak Jeong et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Revisiting Cardiac Cellular CompositionNovelty and Significance

(2015) Alexander R. Pinto et al.   CIRCULATION RESEARCH

Targeting the TGFβ signalling pathway in disease

(2012) Rosemary J. Akhurst et al.   NATURE REVIEWS DRUG DISCOVERY

Redirecting Valvular Myofibroblasts into Dormant Fibroblasts through Light-mediated Reduction in Substrate Modulus

(2012) Huan Wang et al.   PLoS One

Congestive Heart Failure Effects on Atrial Fibroblast Phenotype: Differences between Freshly-Isolated and Cultured Cells

(2012) Kristin Dawson et al.   PLoS One

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

Transforming growth factor (TGF)-β signaling in cardiac remodeling

(2010) Marcin Dobaczewski et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Myocardial remodeling after infarction: the role of myofibroblasts

(2009) Susanne W. M. van den Borne et al.   Nature Reviews Cardiology

Transforming growth factor beta inhibition increases mortality and left ventricular dilatation after myocardial infarction

(2008) Stefan Frantz et al.   BASIC RESEARCH IN CARDIOLOGY

Embryonic cardiomyocytes beat best on a matrix with heart-like elasticity: scar-like rigidity inhibits beating

(2008) A. J. Engler et al.   JOURNAL OF CELL SCIENCE