Exacerbated post‐infarct pathological myocardial remodelling in diabetes is associated with impaired autophagy and aggravated NLRP3 inflammasome activation

Fat‐1 transgenic mice rich in endogenous omega‐3 fatty acids are protected from lipopolysaccharide‐induced cardiac dysfunction

(2021) Shuai Mao et al.   ESC Heart Failure

Type 2 Diabetes and Myocardial Infarction: Recent Clinical Evidence and Perspective

(2021) Jing Cui et al.   Frontiers in Cardiovascular Medicine

Loss of autophagy protein ATG5 impairs cardiac capacity in mice and humans through diminishing mitochondrial abundance and disrupting Ca2+ cycling

(2021) Senka Ljubojević-Holzer et al.   CARDIOVASCULAR RESEARCH

Empagliflozin Blunts Worsening Cardiac Dysfunction Associated With Reduced NLRP3 (Nucleotide-Binding Domain-Like Receptor Protein 3) Inflammasome Activation in Heart Failure

(2020) Nikole J. Byrne et al.   Circulation-Heart Failure

18F-FDG PET imaging-monitored anti-inflammatory therapy for acute myocardial infarction: Exploring the role of MCC950 in murine model

(2020) Xiang Li et al.   JOURNAL OF NUCLEAR CARDIOLOGY

A Network of Macrophages Supports Mitochondrial Homeostasis in the Heart

(2020) José A. Nicolás-Ávila et al.   CELL

Interplay Between NLRP3 Inflammasome and Autophagy

(2020) Monika Biasizzo et al.   Frontiers in Immunology

Glucose Metabolism is Required for Platelet Hyperactivation in a Murine Model of Type 1 Diabetes Mellitus

(2019) Trevor P. Fidler et al.   DIABETES

Dysglycemia and increased left ventricle mass in normotensive patients admitted with a first myocardial infarction: prognostic implications of dysglycemia during 14 years of follow-up

(2019) Gokulan Pararajasingam et al.   BMC Cardiovascular Disorders

Metformin Enhances Autophagy and Provides Cardioprotection in δ-Sarcoglycan Deficiency-Induced Dilated Cardiomyopathy

(2019) Hiromitsu Kanamori et al.   Circulation-Heart Failure

Extent of coronary artery disease is associated with myocardial infarction and mortality in patients with diabetes mellitus

(2019) Christine Gyldenkerne et al.   Clinical Epidemiology

The NLRP3 inflammasome in acute myocardial infarction

(2019) Adolfo Gabriele Mauro et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Exploration of Multiple Signaling Pathways Through Which Sodium Tanshinone IIA Sulfonate Attenuates Pathologic Remodeling Experimental Infarction

(2019) Shuai Mao et al.   Frontiers in Pharmacology

NLRP3 Inflammasome Promotes Myocardial Remodeling During Diet-Induced Obesity

(2019) Marina Sokolova et al.   Frontiers in Immunology

Guidelines for evaluating myocardial cell death

(2019) Paras K Mishra et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Combined ischemic and rapamycin preconditioning alleviated liver ischemia and reperfusion injury by restoring autophagy in aged mice

(2019) Tao Jiang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Dissociation of mitochondrial HK-II elicits mitophagy and confers cardioprotection against ischemia

(2019) Valerie P. Tan et al.   Cell Death & Disease

Intermittent Hypoxia Induces Autophagy to Protect Cardiomyocytes From Endoplasmic Reticulum Stress and Apoptosis

(2019) Jui-Chih Chang et al.   Frontiers in Physiology

Exosome Treatment Enhances Anti-Inflammatory M2 Macrophages and Reduces Inflammation-Induced Pyroptosis in Doxorubicin-Induced Cardiomyopathy

(2019) Dinender K. Singla et al.   Cells

NLRP3 Inflammasome Regulates Development of Systemic Inflammatory Response and Compensatory Anti-Inflammatory Response Syndromes in Mice With Acute Pancreatitis

(2019) Matthias Sendler et al.   GASTROENTEROLOGY

Caspase-1 inhibition by VX-765 administered at reperfusion in P2Y12 receptor antagonist-treated rats provides long-term reduction in myocardial infarct size and preservation of ventricular function

(2018) Jonathon P. Audia et al.   BASIC RESEARCH IN CARDIOLOGY

Heart Disease and Stroke Statistics—2018 Update: A Report From the American Heart Association

(2018) Emelia J. Benjamin et al.   CIRCULATION

Tongguan Capsule Mitigates Post-myocardial Infarction Remodeling by Promoting Autophagy and Inhibiting Apoptosis: Role of Sirt1

(2018) Shuai Mao et al.   Frontiers in Physiology

Autophagy and inflammasomes

(2017) James Harris et al.   MOLECULAR IMMUNOLOGY

The NLRP3 inflammasome in acute myocardial infarction

(2017) Stefano Toldo et al.   Nature Reviews Cardiology

Tanshinone IIA inhibits angiotensin II induced extracellular matrix remodeling in human cardiac fibroblasts — Implications for treatment of pathologic cardiac remodeling

(2016) Shuai Mao et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

The role of the autophagy in myocardial ischemia/reperfusion injury

(2015) Sai Ma et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The Importance of NLRP3 Inflammasome in Heart Failure

(2015) Brittany Butts et al.   JOURNAL OF CARDIAC FAILURE

Berberine improves pressure overload-induced cardiac hypertrophy and dysfunction through enhanced autophagy

(2014) Ming-Hui Li et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Role of NLRP3 (cryopyrin) in acute myocardial infarction

(2013) Eleonora Mezzaroma et al.   CARDIOVASCULAR RESEARCH

PRAS40 prevents development of diabetic cardiomyopathy and improves hepatic insulin sensitivity in obesity

(2013) Mirko Völkers et al.   EMBO Molecular Medicine

Mammalian Target of Rapamycin (mTOR) Inhibition with Rapamycin Improves Cardiac Function in Type 2 Diabetic Mice

(2013) Anindita Das et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effects of saxagliptin and sitagliptin on glycaemic control and pancreatic β-cell mass in a streptozotocin-induced mouse model of type 2 diabetes

(2012) S. M. Poucher et al.   DIABETES OBESITY & METABOLISM

Autophagy Regulates IL-23 Secretion and Innate T Cell Responses through Effects on IL-1 Secretion

(2012) C. Peral de Castro et al.   JOURNAL OF IMMUNOLOGY

The inflammasome promotes adverse cardiac remodeling following acute myocardial infarction in the mouse

(2011) E. Mezzaroma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production

(2008) Tatsuya Saitoh et al.   NATURE