Mycobacterial Adhesion: From Hydrophobic to Receptor-Ligand Interactions

Mycobacterium tuberculosis Glyceraldehyde‐3‐phosphate dehydrogenase plays a dual role‐as an adhesin and as a receptor for Plasmin(ogen)

(2021) Zahid Gani et al.   CELLULAR MICROBIOLOGY

Rv1717 Is a Cell Wall - Associated β-Galactosidase of Mycobacterium tuberculosis That Is Involved in Biofilm Dispersion

(2021) Suman Bharti et al.   Frontiers in Microbiology

Biofilm formation in the lung contributes to virulence and drug tolerance of Mycobacterium tuberculosis

(2021) Poushali Chakraborty et al.   Nature Communications

Beyond the Wall: Exopolysaccharides in the Biofilm Lifestyle of Pathogenic and Beneficial Plant-Associated Pseudomonas

(2021) Zaira Heredia-Ponce et al.   Microorganisms

Inhibition of Streptococcus mutans biofilm formation by strategies targeting the metabolism of exopolysaccharides

(2021) Yongwang Lin et al.   CRITICAL REVIEWS IN MICROBIOLOGY

M. tuberculosis curli pili (MTP) is associated with alterations in carbon, fatty acid and amino acid metabolism in a THP-1 macrophage infection model

(2021) Shinese Ashokcoomar et al.   MICROBIAL PATHOGENESIS

Stepwise pathogenic evolution of Mycobacterium abscessus

(2021) Josephine M. Bryant et al.   SCIENCE

Mycobacterium abscessus in cystic fibrosis

(2021) Rossa Brugha et al.   SCIENCE

Structural Basis of Ligand Selectivity by a Bacterial Adhesin Lectin Involved in Multispecies Biofilm Formation

(2021) Shuaiqi Guo et al.   mBio

Rediscovering bacterial exopolysaccharides of terrestrial and marine origins: novel insights on their distribution, biosynthesis, biotechnological production, and future perspectives

(2021) Ahmed Zayed et al.   CRITICAL REVIEWS IN BIOTECHNOLOGY

Bacterial Exopolysaccharides: Insight into Their Role in Plant Abiotic Stress Tolerance

(2021) Neeta Bhagat et al.   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

AFM Identifies a Protein Complex Involved in Pathogen Adhesion Which Ruptures at Three Nanonewtons

(2021) Constance Chantraine et al.   NANO LETTERS

Underwhelming or Misunderstood? Genetic Variability of Pattern Recognition Receptors in Immune Responses and Resistance to Mycobacterium tuberculosis

(2021) Jean-Yves Dubé et al.   Frontiers in Immunology

The respiratory microbiome and nontuberculous mycobacteria: an emerging concern in human health

(2021) Christina S. Thornton et al.   European Respiratory Review

Carbohydrates from Pseudomonas aeruginosa biofilms interact with immune C-type lectins and interfere with their receptor function

(2021) Sonali Singh et al.   npj Biofilms and Microbiomes

Mechanomicrobiology: how bacteria sense and respond to forces

(2020) Yves F. Dufrêne et al.   NATURE REVIEWS MICROBIOLOGY

Non-tuberculous mycobacteria and the rise of Mycobacterium abscessus

(2020) Matt D. Johansen et al.   NATURE REVIEWS MICROBIOLOGY

How Microbes Use Force To Control Adhesion

(2020) Albertus Viljoen et al.   JOURNAL OF BACTERIOLOGY

Synthetic mycobacterial molecular patterns partially complete Freund’s adjuvant

(2020) Jean-Yves Dubé et al.   Scientific Reports

Mechanical Forces between Mycobacterial Antigen 85 Complex and Fibronectin

(2020) Albertus Viljoen et al.   Cells

The versatile Pseudomonas aeruginosa biofilm matrix protein CdrA promotes aggregation through different extracellular EPS interactions

(2020) Courtney Reichhardt et al.   JOURNAL OF BACTERIOLOGY

Binding Strength of Gram-Positive Bacterial Adhesins

(2020) Yves F. Dufrêne et al.   Frontiers in Microbiology

Mycobacterium tuberculosis curli pili (MTP) is associated with significant host metabolic pathways in an A549 epithelial cell infection model and contributes to the pathogenicity of Mycobacterium tuberculosis

(2020) K. S. Reedoy et al.   Metabolomics

Mycobacterium tuberculosis curli pili (MTP) deficiency is associated with alterations in cell wall biogenesis, fatty acid metabolism and amino acid synthesis

(2020) S. Ashokcoomar et al.   Metabolomics

O-Methylation of the Glycopeptidolipid Acyl Chain Defines Surface Hydrophobicity of Mycobacterium abscessus and Macrophage Invasion

(2020) Wassim Daher et al.   ACS Infectious Diseases

A protein fragment of Rv3194c located on mycobacterial cell surface efficiently prevents adhesion of recombinant Mycobacterium smegmatis, and promises a new anti-adhesive drug

(2020) Dongyue Zhao et al.   MICROBIAL PATHOGENESIS

Lectins of Mycobacterium tuberculosis – rarely studied proteins

(2019) Katharina Kolbe et al.   Beilstein Journal of Organic Chemistry

The Mycobacterium tuberculosis capsule: a cell structure with key implications in pathogenesis

(2019) Rainer Kalscheuer et al.   BIOCHEMICAL JOURNAL

The Pseudomonas aeruginosa lectin LecB binds to the exopolysaccharide Psl and stabilizes the biofilm matrix

(2019) Daniel Passos da Silva et al.   Nature Communications

Cyclipostins and Cyclophostin Analogues as Multitarget Inhibitors That Impair Growth of Mycobacterium abscessus

(2019) Abdeldjalil Madani et al.   ACS Infectious Diseases

Unraveling the Structure of the Mycobacterial Envelope

(2019) Mamadou Daffé et al.   Microbiology Spectrum

The cell surface adhesins of Mycobacterium tuberculosis

(2019) Vivek Vinod et al.   MICROBIOLOGICAL RESEARCH

Cyclophostin and Cyclipostins analogues, new promising molecules to treat mycobacterial-related diseases

(2018) Phuong Chi Nguyen et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Rv0613c/MSMEG_1285 Interacts with HBHA and Mediates Its Proper Cell-Surface Exposure in Mycobacteria

(2018) Romain Veyron-Churlet et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cyclipostins and cyclophostin analogs inhibit the antigen 85C fromMycobacterium tuberculosisbothin vitroandin vivo

(2018) Albertus Viljoen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bacterial adhesion at the single-cell level

(2018) Cecile Berne et al.   NATURE REVIEWS MICROBIOLOGY

Molecular mechanism of extreme mechanostability in a pathogen adhesin

(2018) Lukas F. Milles et al.   SCIENCE

A Simple and Rapid Gene Disruption Strategy in Mycobacterium abscessus: On the Design and Application of Glycopeptidolipid Mutants

(2018) Albertus Viljoen et al.   Frontiers in Cellular and Infection Microbiology

Mannose-capped lipoarabinomannan in Mycobacterium tuberculosis pathogenesis

(2018) Joanne Turner et al.   Pathogens and Disease

Transmission of Leprosy: A Study of Skin and Nasal Secretions of Household Contacts of Leprosy Patients Using PCR

(2018) Charles K. Job et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

CdrA Interactions within the Pseudomonas aeruginosa Biofilm Matrix Safeguard It from Proteolysis and Promote Cellular Packing

(2018) Courtney Reichhardt et al.   mBio

Heparin-Binding Hemagglutinin Adhesin (HBHA) Is Involved in Intracytosolic Lipid Inclusions Formation in Mycobacteria

(2018) Dominique Raze et al.   Frontiers in Microbiology

Cutaneous Mycobacterial Infections

(2018) Carlos Franco-Paredes et al.   CLINICAL MICROBIOLOGY REVIEWS

Calcium stabilizes the strongest protein fold

(2018) Lukas F. Milles et al.   Nature Communications

Deciphering the molecular basis of mycobacteria and lipoglycan recognition by the C-type lectin Dectin-2

(2018) Alexiane Decout et al.   Scientific Reports

Characterization of a mycobacterial cellulase and its impact on biofilm- and drug-induced cellulose production

(2017) Niël Van Wyk et al.   GLYCOBIOLOGY

Mycobacterium tuberculosisinhibits human innate immune responses via the production of TLR2 antagonist glycolipids

(2017) Landry Blanc et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rational design of adjuvants targeting the C-type lectin Mincle

(2017) Alexiane Decout et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A structural overview of mycobacterial adhesins: Key biomarkers for diagnostics and therapeutics

(2017) Flavia Squeglia et al.   PROTEIN SCIENCE

Recognition of Mycobacterial Lipids by Immune Receptors

(2017) Eri Ishikawa et al.   TRENDS IN IMMUNOLOGY

Cyclipostins and Cyclophostin analogs as promising compounds in the fight against tuberculosis

(2017) Phuong Chi Nguyen et al.   Scientific Reports

Trehalose Polyphleates, External Cell Wall Lipids in Mycobacterium abscessus, Are Associated with the Formation of Clumps with Cording Morphology, Which Have Been Associated with Virulence

(2017) Marta Llorens-Fons et al.   Frontiers in Microbiology

Multidrug-resistant Mycobacterium abscessus threatens patients with cystic fibrosis

(2017) Aaron van Dorn   Lancet Respiratory Medicine

The role of hydrophobicity in tuberculosis evolution and pathogenicity

(2017) Monika Jankute et al.   Scientific Reports

Dissecting the mycobacterial cell envelope and defining the composition of the native mycomembrane

(2017) Laura Chiaradia et al.   Scientific Reports

Against the tide: the role of bacterial adhesion in host colonization

(2016) D. H. Stones et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Evaluation of the role of Mycobacterium tuberculosis pili (MTP) as an adhesin, invasin, and cytokine inducer of epithelial cells

(2016) Saiyur Ramsugit et al.   Brazilian Journal of Infectious Diseases

Treatment of human disease due toMycobacterium bovis: a systematic review

(2016) Zhiyi Lan et al.   EUROPEAN RESPIRATORY JOURNAL

Analysis of the contribution of MTP and the predicted Flp pilus genes to Mycobacterium tuberculosis pathogenesis

(2016) Katherine M. Mann et al.   MICROBIOLOGY-SGM

Deletion of a dehydratase important for intracellular growth and cording renders roughMycobacterium abscessusavirulent

(2016) Iman Halloum et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Emergence and spread of a human-transmissible multidrug-resistant nontuberculous mycobacterium

(2016) Josephine M. Bryant et al.   SCIENCE

Identification of Bicarbonate as a Trigger and Genes Involved with Extracellular DNA Export in Mycobacterial Biofilms

(2016) Sasha J. Rose et al.   mBio

Thiol reductive stress induces cellulose-anchored biofilm formation in Mycobacterium tuberculosis

(2016) Abhishek Trivedi et al.   Nature Communications

Optical and force nanoscopy in microbiology

(2016) Jie Xiao et al.   Nature Microbiology

Chronic pulmonary disease withMycobacterium abscessuscomplex is a biofilm infection

(2015) Tavs Qvist et al.   EUROPEAN RESPIRATORY JOURNAL

From hydration repulsion to dry adhesion between asymmetric hydrophilic and hydrophobic surfaces

(2015) Matej Kanduč et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ancient mycobacterial lipids: Key reference biomarkers in charting the evolution of tuberculosis

(2015) David E. Minnikin et al.   TUBERCULOSIS

Allelic variation contributes to bacterial host specificity

(2015) Min Yue et al.   Nature Communications

Manipulation of the endocytic pathway and phagocyte functions by Mycobacterium tuberculosis lipoarabinomannan

(2015) Isabelle Vergne et al.   Frontiers in Cellular and Infection Microbiology

Mycobacterium avium Possesses Extracellular DNA that Contributes to Biofilm Formation, Structural Integrity, and Tolerance to Antibiotics

(2015) Sasha J. Rose et al.   PLoS One

Host Evasion and Exploitation Schemes of Mycobacterium tuberculosis

(2014) C.J. Cambier et al.   CELL

Structure, interactions and evolutionary implications of a domain-swapped lectin dimer from Mycobacterium smegmatis

(2014) Dhabaleswar Patra et al.   GLYCOBIOLOGY

Dectin-2 Is a Direct Receptor for Mannose-Capped Lipoarabinomannan of Mycobacteria

(2014) Akiko Yonekawa et al.   IMMUNITY

Mycobacterium tuberculosis Pili Promote Adhesion to and Invasion of THP-1 Macrophages

(2014) Saiyur Ramsugit et al.   JAPANESE JOURNAL OF INFECTIOUS DISEASES

Inactivation of theMycobacterium tuberculosisAntigen 85 Complex by Covalent, Allosteric Inhibitors

(2014) Lorenza Favrot et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mannan Chain Length Controls Lipoglycans Signaling via and Binding to TLR2

(2014) J. Nigou et al.   JOURNAL OF IMMUNOLOGY

Mycobacterium tuberculosis adhesins: potential biomarkers as anti-tuberculosis therapeutic and diagnostic targets

(2014) V. S. Govender et al.   MICROBIOLOGY-SGM

The binding force of the staphylococcal adhesin SdrG is remarkably strong

(2014) Philippe Herman et al.   MOLECULAR MICROBIOLOGY

Mycobacterium abscessus cording prevents phagocytosis and promotes abscess formation

(2014) A. Bernut et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mycobacterium tuberculosis pili (MTP), a putative biomarker for a tuberculosis diagnostic test

(2014) Natasha Naidoo et al.   TUBERCULOSIS

Genetics study and transmission electron microscopy of pili in susceptible and resistant clinical isolates of Mycobacterium tuberculosis

(2014) Hossein Hosseini et al.   Asian Pacific Journal of Tropical Medicine

Mycobacterium ulcerans Fails to Infect through Skin Abrasions in a Guinea Pig Infection Model: Implications for Transmission

(2014) Heather R. Williamson et al.   PLoS Neglected Tropical Diseases

Expression of antimicrobial drug tolerance by attached communities ofMycobacterium tuberculosis

(2014) David F. Ackart et al.   Pathogens and Disease

Characterization of mycobacterial triacylglycerols and monomeromycolyl diacylglycerols from Mycobacterium smegmatis biofilm by electrospray ionization multiple-stage and high-resolution mass spectrometry

(2013) Georgiana E. Purdy et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Pili contribute to biofilm formation in vitro in Mycobacterium tuberculosis

(2013) Saiyur Ramsugit et al.   ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY

Interaction of Mycobacterium leprae with Human Airway Epithelial Cells: Adherence, Entry, Survival, and Identification of Potential Adhesins by Surface Proteome Analysis

(2013) Carlos A. M. Silva et al.   INFECTION AND IMMUNITY

MmpL11 Protein Transports Mycolic Acid-containing Lipids to the Mycobacterial Cell Wall and Contributes to Biofilm Formation in Mycobacterium smegmatis

(2013) Sophia A. Pacheco et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mycobacteria manipulate macrophage recruitment through coordinated use of membrane lipids

(2013) C. J. Cambier et al.   NATURE

Chaperone-Usher Fimbriae of Escherichia coli

(2013) Daniël J. Wurpel et al.   PLoS One

Identification of Novel Adhesins of M. tuberculosis H37Rv Using Integrated Approach of Multiple Computational Algorithms and Experimental Analysis

(2013) Sanjiv Kumar et al.   PLoS One

Mannodendrimers prevent acute lung inflammation by inhibiting neutrophil recruitment

(2013) E. Blattes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Keto-Mycolic Acid-Dependent Pellicle Formation Confers Tolerance to Drug-Sensitive Mycobacterium tuberculosis

(2013) D. Sambandan et al.   mBio

Mycobacterial HBHA induces endoplasmic reticulum stress-mediated apoptosis through the generation of reactive oxygen species and cytosolic Ca2+ in murine macrophage RAW 264.7 cells

(2013) J-A Choi et al.   Cell Death & Disease

Mechanism of inhibition of Mycobacterium tuberculosis antigen 85 by ebselen

(2013) Lorenza Favrot et al.   Nature Communications

Bacterial cell wall macroamphiphiles: Pathogen-/microbe-associated molecular patterns detected by mammalian innate immune system

(2012) Aurélie Ray et al.   BIOCHIMIE

Elastin, a Novel Extracellular Matrix Protein Adhering to Mycobacterial Antigen 85 Complex

(2012) Chih-Jung Kuo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RapA2 Is a Calcium-binding Lectin Composed of Two Highly Conserved Cadherin-like Domains That Specifically RecognizeRhizobium leguminosarumAcidic Exopolysaccharides

(2012) Patricia L. Abdian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Biology of the Toll-Like Receptor Family

(2011) Jin Young Kang et al.   Annual Review of Biochemistry

Fibronectin attachment protein from bacillus Calmette-Guerin as targeting agent for bladder tumor cells

(2011) Brian G. Coon et al.   INTERNATIONAL JOURNAL OF CANCER

Novel Mycobacteria Antigen 85 Complex Binding Motif on Fibronectin

(2011) Chih-Jung Kuo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Location of Intra- and Extracellular M. tuberculosis Populations in Lungs of Mice and Guinea Pigs during Disease Progression and after Drug Treatment

(2011) Donald R. Hoff et al.   PLoS One

Lipoglycans Contribute to Innate Immune Detection of Mycobacteria

(2011) Shyam Krishna et al.   PLoS One

Recent advances in deciphering the contribution of Mycobacterium tuberculosis lipids to pathogenesis

(2011) Olivier Neyrolles et al.   TUBERCULOSIS

Heparan Sulfate Proteoglycans

(2011) S. Sarrazin et al.   Cold Spring Harbor Perspectives in Biology

Targeting of Mycobacterium tuberculosis Heparin-Binding Hemagglutinin to Mitochondria in Macrophages

(2011) Hosung Sohn et al.   PLoS Pathogens

Cloning, expression, purification, crystallization and preliminary X-ray studies of a secreted lectin (Rv1419) fromMycobacterium tuberculosis

(2010) Dhabaleswar Patra et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Overexpression of proinflammatory TLR-2-signalling lipoproteins in hypervirulent mycobacterial variants

(2010) Anne-Laure Roux et al.   CELLULAR MICROBIOLOGY

Enzymatic Hydrolysis of Trehalose Dimycolate Releases Free Mycolic Acids during Mycobacterial Growth in Biofilms

(2010) Anil K. Ojha et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hospital water filters as a source of Mycobacterium avium complex

(2010) J. O. Falkinham   JOURNAL OF MEDICAL MICROBIOLOGY

Force Spectroscopy of the Interaction Between Mycobacterial Adhesins and Heparan Sulphate Proteoglycan Receptors

(2009) Vincent Dupres et al.   CHEMPHYSCHEM

Mycobacterium tuberculosisRv1419 encodes a secreted 13 kDa lectin with immunological reactivity during human tuberculosis

(2009) Lucas Nogueira et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Role of Phosphatidylinositol Mannosides in the Interaction between Mycobacteria and DC-SIGN

(2009) N. N. Driessen et al.   INFECTION AND IMMUNITY

Mycobacterium avium subsp. paratuberculosis Fibronectin Attachment Protein Activates Dendritic Cells and Induces a Th1 Polarization

(2009) J. S. Lee et al.   INFECTION AND IMMUNITY

Direct measurement of Mycobacterium–fibronectin interactions

(2009) Claire Verbelen et al.   Integrative Biology

Surrounded by mycobacteria: nontuberculous mycobacteria in the human environment

(2009) J.O. Falkinham et al.   JOURNAL OF APPLIED MICROBIOLOGY

Identification of Mycobacterial  -Glucan As a Novel Ligand for DC-SIGN: Involvement of Mycobacterial Capsular Polysaccharides in Host Immune Modulation

(2009) J. Geurtsen et al.   JOURNAL OF IMMUNOLOGY

Mycobacterium abscessus Glycopeptidolipids Mask Underlying Cell Wall Phosphatidyl-myo-Inositol Mannosides Blocking Induction of Human Macrophage TNF-  by Preventing Interaction with TLR2

(2009) E. R. Rhoades et al.   JOURNAL OF IMMUNOLOGY

Soluble CD36 Ectodomain Binds Negatively Charged Diacylglycerol Ligands and Acts as a Co-Receptor for TLR2

(2009) Maximiliano J. Jimenez-Dalmaroni et al.   PLoS One

Interaction of the Mycobacterial Heparin-Binding Hemagglutinin with Actin, as Evidenced by Single-Molecule Force Spectroscopy

(2008) C. Verbelen et al.   JOURNAL OF BACTERIOLOGY

Acute Respiratory Failure Involving an R Variant of Mycobacterium abscessus

(2008) E. Catherinot et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Mutation in the DC-SIGN cytoplasmic triacidic cluster motif markedly attenuates receptor activity for phagocytosis and endocytosis of mannose-containing ligands by human myeloid cells

(2008) Abul K. Azad et al.   JOURNAL OF LEUKOCYTE BIOLOGY