A System-Level Mechanism of Anmyungambi Decoction for Obesity: A Network Pharmacological Approach

Effect of Quercetin on Lipids Metabolism Through Modulating the Gut Microbial and AMPK/PPAR Signaling Pathway in Broilers

(2021) Mi Wang et al.   Frontiers in Cell and Developmental Biology

STAT3 phosphorylation in central leptin resistance

(2021) Huimin Liu et al.   Nutrition & Metabolism

Leptin and Obesity: Role and Clinical Implication

(2021) Milan Obradovic et al.   Frontiers in Endocrinology

Applications of Network Pharmacology in Traditional Chinese Medicine Research

(2020) Zhuchen Zhou et al.   Evidence-based Complementary and Alternative Medicine

Systematic Elucidation of the Potential Mechanism of Erzhi Pill against Drug-Induced Liver Injury via Network Pharmacology Approach

(2020) Shao-jie Huang et al.   Evidence-based Complementary and Alternative Medicine

Ephedrae Herba in combination with herbal medicine (Zhizichi decoction and Phellodendri Cortex) for weight reduction: a case series

(2020) Eunji Lee et al.   Integrative Medicine Research

Network Pharmacology Databases for Traditional Chinese Medicine: Review and Assessment

(2019) Runzhi Zhang et al.   Frontiers in Pharmacology

The Methodological Trends of Traditional Herbal Medicine Employing Network Pharmacology

(2019) Won-Yung Lee et al.   Biomolecules

Exploring the combination and modular characteristics of herbs for alopecia treatment in traditional Chinese medicine: an association rule mining and network analysis study

(2018) Jungtae Leem et al.   BMC Complementary and Alternative Medicine

DNA-binding activity of STAT3 increased in hypothalamus of DIO mice; the reduction of STAT3 phosphorylation may facilitate leptin signaling

(2018) Liang Xu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The PI3K/AKT pathway in obesity and type 2 diabetes

(2018) Xingjun Huang et al.   International Journal of Biological Sciences

Herbal Medicine for the Treatment of Obesity: An Overview of Scientific Evidence from 2007 to 2017

(2017) Yanfei Liu et al.   Evidence-based Complementary and Alternative Medicine

Quercetin induces apoptosis and autophagy in primary effusion lymphoma cells by inhibiting PI3K/AKT/mTOR and STAT3 signaling pathways

(2017) Marisa Granato et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Quercetin prevents alcohol‑induced liver injury through targeting of PI3K/Akt/nuclear factor‑κB and STAT3 signaling pathway

(2017) Minglin Zhu et al.   Experimental and Therapeutic Medicine

DisGeNET: a comprehensive platform integrating information on human disease-associated genes and variants

(2016) Janet Piñero et al.   NUCLEIC ACIDS RESEARCH

Berberine Increases Doxorubicin Sensitivity by Suppressing STAT3 in Lung Cancer

(2015) Ting Zhu et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

TM-MC: a database of medicinal materials and chemical compounds in Northeast Asian traditional medicine

(2015) Sang-Kyun Kim et al.   BMC Complementary and Alternative Medicine

Physiological adaptations to weight loss and factors favouring weight regain

(2015) F L Greenway   INTERNATIONAL JOURNAL OF OBESITY

Limonin, a Component of Dictamni Radicis Cortex, Inhibits Eugenol-Induced Calcium and cAMP Levels and PKA/CREB Signaling Pathway in Non-Neuronal 3T3-L1 Cells

(2015) Yeo Yoon et al.   MOLECULES

STITCH 5: augmenting protein–chemical interaction networks with tissue and affinity data

(2015) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Adipocytokines in obesity and metabolic disease

(2014) Haiming Cao   JOURNAL OF ENDOCRINOLOGY

Quercetin inhibits AMPK/TXNIP activation and reduces inflammatory lesions to improve insulin signaling defect in the hypothalamus of high fructose-fed rats

(2014) Qing-Yu Zhang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Evodiamine Inhibits Insulin-Stimulated mTOR-S6K Activation and IRS1 Serine Phosphorylation in Adipocytes and Improves Glucose Tolerance in Obese/Diabetic Mice

(2014) Ting Wang et al.   PLoS One

Quercetin exerts anti-melanoma activities and inhibits STAT3 signaling

(2013) Hui-Hui Cao et al.   BIOCHEMICAL PHARMACOLOGY

A gene signature based method for identifying subtypes and subtype-specific drivers in cancer with an application to medulloblastoma

(2013) Peikai Chen et al.   BMC BIOINFORMATICS

Amniotic fluid stem cells prevent β-cell injury

(2013) Valentina Villani et al.   CYTOTHERAPY

FAM3A activates PI3K p110α/Akt signaling to ameliorate hepatic gluconeogenesis and lipogenesis

(2013) Chunjiong Wang et al.   HEPATOLOGY

Genistein sensitizes hepatic insulin signaling and modulates lipid regulatory genes through p70 ribosomal S6 kinase-1 inhibition in high-fat–high-fructose diet-fed mice

(2013) Elumalai Arunkumar et al.   PHARMACEUTICAL BIOLOGY

Evodiamine inhibits STAT3 signaling by inducing phosphatase shatterproof 1 in hepatocellular carcinoma cells

(2012) Jie Yang et al.   CANCER LETTERS

Quantifying the chemical beauty of drugs

(2012) G. Richard Bickerton et al.   Nature Chemistry

Limitations in anti-obesity drug development: the critical role of hunger-promoting neurons

(2012) Marcelo O. Dietrich et al.   NATURE REVIEWS DRUG DISCOVERY

ROS Acts as a Double-Edged Sword in the Pathogenesis of Type 2 Diabetes Mellitus: Is Nrf2 a Potential Target for the Treatment?

(2011) X. Wang et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Inhibition of Preadipocyte Differentiation and Lipid Accumulation by Orengedokuto Treatment of 3T3-L1 Cultures

(2011) Nobutomo Ikarashi et al.   PHYTOTHERAPY RESEARCH

Tissue-specific Functions in the Fatty Acid-binding Protein Family

(2010) Judith Storch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Feed-forward signaling of TNF-α and NF-κB via IKK-β pathway contributes to insulin resistance and coronary arteriolar dysfunction in type 2 diabetic mice

(2009) Jiyeon Yang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Regulation of AMP-activated protein kinase by cAMP in adipocytes: Roles for phosphodiesterases, protein kinase B, protein kinase A, Epac and lipolysis

(2009) Bilal Omar et al.   CELLULAR SIGNALLING

Berberine modulates insulin signaling transduction in insulin-resistant cells

(2009) Li-Zhong Liu et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Molecular Mechanisms of Alcoholic Fatty Liver

(2008) Vishnudutt Purohit et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Adipocytokines and the Metabolic Complications of Obesity

(2008) Neda Rasouli et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The Human Protein Atlas-a tool for pathology

(2008) F Pontén et al.   JOURNAL OF PATHOLOGY