Biomaterial-induced conversion of quiescent cardiomyocytes into pacemaker cells in rats

Modulating Cell Fate as a Therapeutic Strategy

(2018) Brian Lin et al.   Cell Stem Cell

A systems mechanobiology model to predict cardiac reprogramming outcomes on different biomaterials

(2018) Yen P. Kong et al.   BIOMATERIALS

Effects of long-term exercise on arrhythmogenesis in aged hypertensive rats

(2018) Yen-Ling Sung et al.   COMPUTERS IN BIOLOGY AND MEDICINE

Impact of Biomaterials on Differentiation and Reprogramming Approaches for the Generation of Functional Cardiomyocytes

(2018) Camilla Paoletti et al.   Cells

Reduced capacity of autonomic and baroreflex control associated with sleep pattern in spontaneously hypertensive rats with a nondipping profile

(2017) Chieh-Wen Chen et al.   JOURNAL OF HYPERTENSION

Morphological transformation of hBMSC from 2D monolayer to 3D microtissue on low-crystallinity SF-PCL patch with promotion of cardiomyogenesis

(2017) Hsin-Yu Lo et al.   Journal of Tissue Engineering and Regenerative Medicine

Next-generation pacemakers: from small devices to biological pacemakers

(2017) Eugenio Cingolani et al.   Nature Reviews Cardiology

Live imaging molecular changes in junctional tension upon VE-cadherin in zebrafish

(2017) Anne Karine Lagendijk et al.   Nature Communications

A biomaterial approach to cell reprogramming and differentiation

(2017) Joseph Long et al.   Journal of Materials Chemistry B

Biochemical and biomechanical properties of the pacemaking sinoatrial node extracellular matrix are distinct from contractile left ventricular matrix

(2017) Jessica M. Gluck et al.   PLoS One

Mechanical Forces Reshape Differentiation Cues That Guide Cardiomyogenesis

(2016) Cassandra L. Happe et al.   CIRCULATION RESEARCH

Promoting Cardiomyogenesis of hBMSC with a Forming Self-Assembly hBMSC Microtissues/HA-GRGD/SF-PCL Cardiac Patch Is Mediated by the Synergistic Functions of HA-GRGD

(2016) Tze-Wen Chung et al.   MACROMOLECULAR BIOSCIENCE

Sinoatrial node cardiomyocytes derived from human pluripotent cells function as a biological pacemaker

(2016) Stephanie I Protze et al.   NATURE BIOTECHNOLOGY

Single-cell transcriptome and epigenomic reprogramming of cardiomyocyte-derived cardiac progenitor cells

(2016) Xin Chen et al.   Scientific Data

Programming and reprogramming a human heart cell

(2015) M. Sahara et al.   EMBO JOURNAL

ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation

(2015) Gabriele D’Uva et al.   NATURE CELL BIOLOGY

Gene therapy to treat cardiac arrhythmias

(2015) Rossana Bongianino et al.   Nature Reviews Cardiology

Highly Tunable Elastomeric Silk Biomaterials

(2014) Benjamin P. Partlow et al.   ADVANCED FUNCTIONAL MATERIALS

Wnt-induced transcriptional activation is exclusively mediated by TCF/LEF

(2014) Jurian Schuijers et al.   EMBO JOURNAL

Gene Therapy and Biological Pacing

(2014) Michael R. Rosen   NEW ENGLAND JOURNAL OF MEDICINE

Integrative ChIP-seq/Microarray Analysis Identifies a CTNNB1 Target Signature Enriched in Intestinal Stem Cells and Colon Cancer

(2014) Kazuhide Watanabe et al.   PLoS One

Improving cardiac rhythm with a biological pacemaker

(2014) N. V. Munshi et al.   SCIENCE

Use of differentiated pluripotent stem cells in replacement therapy for treating disease

(2014) I. J. Fox et al.   SCIENCE

Direct reprogramming of mouse fibroblasts to cardiomyocyte-like cells using Yamanaka factors on engineered poly(ethylene glycol) (PEG) hydrogels

(2013) Amanda W. Smith et al.   BIOMATERIALS

Pluripotent Stem Cells Induced from Mouse Somatic Cells by Small-Molecule Compounds

(2013) P. Hou et al.   SCIENCE

Silk fibroin biomaterials for tissue regenerations

(2012) Banani Kundu et al.   ADVANCED DRUG DELIVERY REVIEWS

T-box transcription factor TBX3 reprogrammes mature cardiac myocytes into pacemaker-like cells

(2012) Martijn L. Bakker et al.   CARDIOVASCULAR RESEARCH

2012 ACCF/AHA/HRS Focused Update Incorporated Into the ACCF/AHA/HRS 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities

(2012) Andrew E. Epstein et al.   CIRCULATION

SOX7 regulates the expression of VE-cadherin in the haemogenic endothelium at the onset of haematopoietic development

(2012) G. Costa et al.   DEVELOPMENT

Direct conversion of quiescent cardiomyocytes to pacemaker cells by expression of Tbx18

(2012) Nidhi Kapoor et al.   NATURE BIOTECHNOLOGY

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

(2012) Cole Trapnell et al.   Nature Protocols

Wnt/β-Catenin Signaling Maintains the Mesenchymal Precursor Pool for Murine Sinus Horn Formation

(2011) Julia Norden et al.   CIRCULATION RESEARCH

Reprogramming cardiomyocyte mechanosensing by crosstalk between integrins and hyaluronic acid receptors

(2011) Anant Chopra et al.   JOURNAL OF BIOMECHANICS

Cardiomyocyte contractile status is associated with differences in fibronectin and integrin interactions

(2010) Xin Wu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Development of the Pacemaker Tissues of the Heart

(2010) Vincent M. Christoffels et al.   CIRCULATION RESEARCH

A Coupled SYSTEM of Intracellular Ca 2+ Clocks and Surface Membrane Voltage Clocks Controls the Timekeeping Mechanism of the Heart’s Pacemaker

(2010) Edward G. Lakatta et al.   CIRCULATION RESEARCH

The Role of the Funny Current in Pacemaker Activity

(2010) Dario DiFrancesco   CIRCULATION RESEARCH

Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation

(2010) Chris Jopling et al.   NATURE

The cardiomyogenic differentiation of rat mesenchymal stem cells on silk fibroin–polysaccharide cardiac patches in vitro

(2009) Ming-Chia Yang et al.   BIOMATERIALS

A regulatory pathway involving Notch1/β-catenin/Isl1 determines cardiac progenitor cell fate.

(2009) Chulan Kwon et al.   NATURE CELL BIOLOGY

VE-cadherin and β-catenin binding dynamics during histamine-induced endothelial hyperpermeability

(2008) Mingzhang Guo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Derivation and performance of an entirely autologous injectable hydrogel delivery system for cell-based therapies

(2008) Nicholas Bryan et al.   BIOMATERIALS

Signalling by neurotrophins and hepatocyte growth factor regulates axon morphogenesis by differential  -catenin phosphorylation

(2008) M. D. David et al.   JOURNAL OF CELL SCIENCE