Review
Clinical Neurology
Huiyuan Liu, Yashu Liu, Mengyuan Shi, Yuhan Zhou, Yuhong Zhao, Yang Xia
Summary: This meta-analysis examined the association between sugar-sweetened beverage (SSB) consumption and cognitive disorders. The results showed a positive association between SSB intake and the prevalence of cognitive disorders, particularly in cohort studies, middle-aged and elderly populations, and individuals who consumed sugar-sweetened soft drinks.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Geriatrics & Gerontology
Hang Su, Xiaokang Sun, Fang Li, Qihao Guo
Summary: This study found that handgrip strength significantly decreased in MCI and AD patients, and stronger handgrip strength was associated with better cognitive performance. Handgrip strength could potentially aid in the early recognition of Chinese AD patients.
Review
Medicine, General & Internal
Leicia Iris de Assuncao Prado, Ana Lucia Junger, Leonardo Ferreira Caixeta, Matias Noll, Cesar de Oliveira, Erika Aparecida Silveira
Summary: This study aims to assess the effectiveness of treating dementia and cognitive decline with methylfolate supplementation in older adults. The main outcomes analyzed will be dementia and changes in cognitive function. Secondary outcomes, such as inflammatory markers and folic acid levels, will also be assessed.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Psychiatry
Azizi Seixas, Farid A. Rajabli, Margaret Pericak-Vance, Girardin L. Jean-Louis, Ioannis Tarnanas
Summary: This study investigated a digital neuro signature biomarker in predicting cognitive functioning and changes in older adults, compared to traditional biomarkers. The study also explored which demographic and clinical factors predicted the digital neuro signature biomarker in cognitively impaired and healthy older adults. The findings suggest that digital biomarkers may offer more reliable predictions of cognitive functioning and changes in older adults compared to traditional biomarkers.
FRONTIERS IN PSYCHIATRY
(2022)
Review
Public, Environmental & Occupational Health
Linghao Meng, Yang Zhang, Shushan Zhang, Fugui Jiang, Leihao Sha, Yajia Lan, Lei Huang
Summary: This study conducted a systematic review and dose-response meta-analysis to explore the association between noise exposure and the risk of dementia. The results showed a positive linear association between noise increment and dementia risk. Additionally, the study indicated that noise exposure may be a specific risk factor for dementia.
FRONTIERS IN PUBLIC HEALTH
(2022)
Review
Clinical Neurology
Jemma Hazan, Michelle Wing, Kathy Y. Liu, Suzanne Reeves, Robert Howard
Summary: This study evaluated the clinical utility of cerebrospinal fluid (CSF) biomarkers in the diagnosis of Alzheimer's disease (AD) in patients with cognitive impairment. The meta-analysis showed that the use of CSF biomarkers led to changes in diagnosis, increased diagnostic confidence, and influenced patient management. Further research is needed to explore the clinical utility of blood-based biomarkers.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
(2023)
Review
Clinical Neurology
Liqing Li, Qi Zhang, Di Yang, Sule Yang, Yulan Zhao, Min Jiang, Xiaofang Wang, Ling Zhao, Qi Liu, Zuxun Lu, Xiaogang Zhou, Yong Gan, Chunmei Wu
Summary: Epidemiological studies have shown that tooth loss may be associated with an increased risk of cognitive decline and dementia. However, some results do not show a significant association. Therefore, we performed a meta-analysis to evaluate this association.
FRONTIERS IN NEUROLOGY
(2023)
Review
Clinical Neurology
Abdul Gofir, Samekto Wibowo, Muhammad Hakimi, David Dwi Putera, Irawan Satriotomo, Mustofa Mustofa
Summary: This study conducted a systematic review and meta-analysis on folic acid treatments for vascular cognitive impairment. The findings suggest that folic acid can effectively lower plasma homocysteine concentration, but it has limited impact on cognitive function.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
(2022)
Review
Cardiac & Cardiovascular Systems
Swarna Vishwanath, Vazhma Qaderi, Claire J. Steves, Christopher M. Reid, Ingrid Hopper, Joanne Ryan
Summary: There is an association between heart failure (HF) and cognitive change and dementia. HF is not significantly associated with dementia, but increases the risk of cognitive impairment. Patients with HF perform worse on cognitive tests.
JOURNAL OF CARDIAC FAILURE
(2022)
Review
Nutrition & Dietetics
Run-ze Zhu, Mei-qing Chen, Zhi-wen Zhang, Tian-yu Wu, Wen-Hong Zhao
Summary: A meta-analysis showed a significant association between omega-3 polyunsaturated fatty acid (PUFA) intake and MCI risk, while other fatty acids were not significantly associated with AD or dementia risk.
Article
Food Science & Technology
Alba Tor-Roca, Alex Sanchez-Pla, Aniko Korosi, Merce Pallas, Paul J. Lucassen, Pol Castellano-Escuder, Ludwig Aigner, Raul Gonzalez-Dominguez, Claudine Manach, Francisco Carmona, Esteban Vegas, Catherine Helmer, Catherine Feart, Sophie Lefevre-Arbogast, Jeanne Neuffer, Hyunah Lee, Sandrine Thuret, Cristina Andres-Lacueva, Cecilia Samieri, Mireia Urpi-Sarda
Summary: This study found that greater adherence to the Mediterranean diet is associated with lower odds of cognitive decline in older adults.
MOLECULAR NUTRITION & FOOD RESEARCH
(2023)
Review
Biochemistry & Molecular Biology
Arkadiusz Dziedzic
Summary: A systematic review and meta-analysis suggests a potential association between periodontitis and cognitive impairment, particularly dementia and Alzheimer's disease. However, the heterogeneity of study designs, methods, and treatment of confounders, as well as the presence of bias, hinders drawing definitive conclusions about the role of periodontitis as a risk factor for age-related cognitive impairment.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Geriatrics & Gerontology
Jun Wang, Xuanlin Li, Siyuan Lei, Dong Zhang, Shujuan Zhang, Hailong Zhang, Jiansheng Li
Summary: This meta-analysis study found a significant association between chronic obstructive pulmonary disease (COPD) and an increased risk of dementia or cognitive impairment. The risk of dementia was most pronounced in COPD patients under the age of 65, while gender did not have a significant impact on the risk of dementia.
FRONTIERS IN AGING NEUROSCIENCE
(2022)
Article
Clinical Neurology
Kevin Kuo, Ya-Ru Zhang, Shi-Dong Chen, Xiao-Yu He, Shu-Yi Huang, Bang-Sheng Wu, Yue-Ting Deng, Liu Yang, Ya-Nan Ou, Yu Guo, Rui-Qi Zhang, Yi Zhang, Lan Tan, Qiang Dong, Wei Cheng, Jin-Tai Yu
Summary: This study analyzed data from the UK Biobank and found that a 5 kg increment in grip strength was associated with lower risks of all types of dementia, while a slow walking pace was associated with increased risks of all types of dementia. These findings highlight the importance of grip strength and walking pace in estimating the risks of dementia.
ALZHEIMERS & DEMENTIA
(2023)
Review
Geriatrics & Gerontology
Huiling Qu, Shida Yang, Zhicheng Yao, Xiaoyu Sun, Huisheng Chen
Summary: This meta-analysis found an association between headache disorders and all-cause dementia, AD, and VaD. It showed that any headache disorder increases the risk of these types of dementia. The risk is slightly higher in females and in retrospective cohorts.
FRONTIERS IN AGING NEUROSCIENCE
(2022)
Article
Nutrition & Dietetics
Setor K. Kunutsor, Jari A. Laukkanen, Jyrki K. Virtanen
Summary: Egg or cholesterol intake is not associated with future risk of venous thromboembolism (VTE) in middle-aged and older Finnish men.
BRITISH JOURNAL OF NUTRITION
(2023)
Article
Peripheral Vascular Disease
Sae Young Jae, Hyun Jeong Kim, Sudhir Kurl, Setor K. Kunutsor, Jari A. Laukkanen
Summary: A study of 1,481 men showed that an exaggerated systolic blood pressure (ESBP) during exercise is associated with an increased risk of cardiovascular disease (CVD) mortality. However, high levels of cardiorespiratory fitness (CRF) do not attenuate this risk.
AMERICAN JOURNAL OF HYPERTENSION
(2023)
Review
Orthopedics
Ifrah Omar, Setor K. Kunutsor, Wendy Bertram, Andrew J. Moore, Ashley W. Blom, Erik Lenguerrand, Michael R. Whitehouse, Vikki Wylde
Summary: This study aimed to understand the current provision of rehabilitation for revision total knee replacement (TKR) in England and evaluate the existing evidence. The study involved an online national survey of education and rehabilitation provision for patients receiving revision TKR in 22 hospitals across England, as well as a systematic review of studies evaluating rehabilitation programs for revision joint replacement. The study identified the need for future research on tailored rehabilitation to optimize patient outcomes following revision TKR.
BMC MUSCULOSKELETAL DISORDERS
(2023)
Letter
Medicine, General & Internal
Setor K. Kunutsor, Jari A. Laukkanen
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
(2023)
Review
Public, Environmental & Occupational Health
Samuel Seidu, Mohammad Abdool, Abdullah Almaqhawi, Thomas J. Wilkinson, Setor K. Kunutsor, Kamlesh Khunti, Tom Yates
Summary: Regular physical activity is associated with a reduced risk of chronic kidney disease (CKD) in the general population, according to a systematic review and meta-analysis of observational cohort studies. However, the quality of the evidence is low.
EUROPEAN JOURNAL OF EPIDEMIOLOGY
(2023)
Review
Orthopedics
Richard L. Donovan, Harvey Johnson, Sherwin Fernando, Michael Foxall-Smith, Michael R. Whitehouse, Ashley W. Blom, Setor K. Kunutsor
Summary: This study compared the use of constrained acetabular components and dual mobility implants in revision total hip arthroplasty (rTHA) and found that dual mobility implants had lower rates of dislocation, re-revision for dislocation, and re-revision for any cause compared to constrained acetabular components. Surgeons should consider these findings when choosing implants for the treatment of instability.
JOURNAL OF ARTHROPLASTY
(2023)
Letter
Cardiac & Cardiovascular Systems
Setor K. K. Kunutsor, Sae Young Jae, Sudhir Kurl, Jari A. Laukkanen
JOURNAL OF CARDIOPULMONARY REHABILITATION AND PREVENTION
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Setor K. Kunutsor, Jari A. Laukkanen
Summary: This editorial discusses the 'U-shaped relationship between apolipoprotein A1 levels and mortality risk in men and women'.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2023)
Article
Geriatrics & Gerontology
Setor K. Kunutsor, Nzechukwu M. Isiozor, Jonathan Myers, Samuel Seidu, Kamlesh Khunti, Jari A. Laukkanen
Summary: Chronic kidney disease (CKD) is a preventable global public health burden. High levels of cardiorespiratory fitness (CRF) are associated with a decreased risk of CKD, but the dose-response relationship and long-term relevance of CRF levels to CKD have not been fully addressed.
Article
Cardiac & Cardiovascular Systems
Nzechukwu M. Isiozor, Setor K. Kunutsor, Ari Voutilainen, Ifeanyichukwu Isiozor, Bamba Gaye, Jussi Kauhanen, Jari A. Laukkanen
Summary: This study aimed to examine the association between cardiovascular health (CVH) metrics and the risk of heart failure (HF) in a Finnish population. The study found that individuals with optimal CVH scores had a lower risk of heart failure compared to those with inadequate CVH scores.
Article
Medicine, General & Internal
Setor K. Kunutsor, Jussi Kauhanen, Jari A. Laukkanen
Summary: This study found that frequent sauna bathing is not associated with impaired renal function or increased risk of chronic kidney disease (CKD).
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
(2023)
Article
Cardiac & Cardiovascular Systems
Jari A. Laukkanen, Nzechukwu M. Isiozor, Peter Willeit, Setor K. Kunutsor
Summary: The study examines the association between hemodynamic gain index (HGI) and cardiovascular disease (CVD) mortality risk. The results show an inverse relationship between HGI and CVD mortality risk, which is partly dependent on cardiorespiratory fitness (CRF) levels.
JOURNAL OF CARDIOPULMONARY REHABILITATION AND PREVENTION
(2023)
Letter
Cardiac & Cardiovascular Systems
Setor K. Kunutsor, Sudhir Kurl, Jari A. Laukkanen
JOURNAL OF CARDIOPULMONARY REHABILITATION AND PREVENTION
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Hassan Khan, Setor K. Kunutsor
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Article
Medicine, General & Internal
Samuel Seidu, Harini Willis, Setor K. Kunutsor, Kamlesh Khunti
Summary: This study assessed and compared the benefits and harms of intensive versus standard blood pressure control in older people with or without diabetes. Analysis of six randomized controlled trials involving 20,985 patients showed that intensive blood pressure control reduces the risk of cardiovascular events in the general population, but its effectiveness in patients with diabetes is uncertain.
JOURNAL OF THE ROYAL SOCIETY OF MEDICINE
(2023)
