TGFβ Drives Metabolic Perturbations during Epithelial Mesenchymal Transition in Pancreatic Cancer: TGFβ Induced EMT in PDAC

Metabolism of Amino Acids in Cancer

(2021) Zhen Wei et al.   Frontiers in Cell and Developmental Biology

Cholecystokinin Receptor Antagonist Improves Efficacy of Chemotherapy in Murine Models of Pancreatic Cancer by Altering the Tumor Microenvironment

(2021) Zoe X. Malchiodi et al.   Cancers

Epithelial to Mesenchymal Transition: A Mechanism that Fuels Cancer Radio/Chemoresistance

(2020) József Dudás et al.   Cells

Shaping Up the Tumor Microenvironment With Cellular Fibronectin

(2020) Georgios Efthymiou et al.   Frontiers in Oncology

Reprogramming of Amino Acid Metabolism in Pancreatic Cancer: Recent Advances and Therapeutic Strategies

(2020) Ruiyuan Xu et al.   Frontiers in Oncology

The enhancement of glycolysis regulates pancreatic cancer metastasis

(2019) Jinshou Yang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Reduced mannosidase MAN1A1 expression leads to aberrant N-glycosylation and impaired survival in breast cancer

(2018) Karen Legler et al.   BRITISH JOURNAL OF CANCER

miR-9-5p inhibits pancreatic cancer cell proliferation, invasion and glutamine metabolism by targeting GOT1

(2018) Juan Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Regulation of the Hippo-YAP Pathway by Glucose Sensor O-GlcNAcylation

(2017) Changmin Peng et al.   MOLECULAR CELL

Role of protein glycosylation in cancer metastasis

(2017) Leticia Oliveira-Ferrer et al.   SEMINARS IN CANCER BIOLOGY

Targeting the Metabolic Reprogramming That Controls Epithelial-to-Mesenchymal Transition in Aggressive Tumors

(2017) Andrea Morandi et al.   Frontiers in Oncology

Overview of pre-clinical and clinical studies targeting angiogenesis in pancreatic ductal adenocarcinoma

(2016) Kelly E. Craven et al.   CANCER LETTERS

BMP-7 attenuated silica-induced pulmonary fibrosis through modulation of the balance between TGF-β/Smad and BMP-7/Smad signaling pathway

(2016) Di Liang et al.   CHEMICO-BIOLOGICAL INTERACTIONS

A lipidomic and metabolomic serum signature from nonhuman primates exposed to ionizing radiation

(2016) Evan L. Pannkuk et al.   Metabolomics

Abrogating cholesterol esterification suppresses growth and metastasis of pancreatic cancer

(2016) J Li et al.   ONCOGENE

Targeting the TGFβ pathway for cancer therapy

(2015) Cindy Neuzillet et al.   PHARMACOLOGY & THERAPEUTICS

Interactive XCMS Online: Simplifying Advanced Metabolomic Data Processing and Subsequent Statistical Analyses

(2014) Harsha Gowda et al.   ANALYTICAL CHEMISTRY

Projecting Cancer Incidence and Deaths to 2030: The Unexpected Burden of Thyroid, Liver, and Pancreas Cancers in the United States

(2014) L. Rahib et al.   CANCER RESEARCH

Mutant p53 Drives Pancreatic Cancer Metastasis through Cell-Autonomous PDGF Receptor β Signaling

(2014) Susann Weissmueller et al.   CELL

Molecular Pathways: Linking Tumor Microenvironment to Epithelial-Mesenchymal Transition in Metastasis

(2014) H.-Y. Jung et al.   CLINICAL CANCER RESEARCH

Cholecystokinin Mediates Progression and Metastasis of Pancreatic Cancer Associated with Dietary Fat

(2014) Gail L. Matters et al.   DIGESTIVE DISEASES AND SCIENCES

Plasma phospholipids identify antecedent memory impairment in older adults

(2014) Mark Mapstone et al.   NATURE MEDICINE

Elevation of circulating branched-chain amino acids is an early event in human pancreatic adenocarcinoma development

(2014) Jared R Mayers et al.   NATURE MEDICINE

Targeting the Transforming Growth Factor-β Signaling in Cancer Therapy

(2013) Yhun Yhong Sheen et al.   Biomolecules & Therapeutics

Hyper-O-GlcNAcylation Is Anti-apoptotic and Maintains Constitutive NF-κB Activity in Pancreatic Cancer Cells

(2013) Zhiyuan Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway

(2013) Jaekyoung Son et al.   NATURE

Retinoic acid alters the proliferation and survival of the epithelium and mesenchyme and suppresses Wnt/β-catenin signaling in developing cleft palate

(2013) X Hu et al.   Cell Death & Disease

TGF-  and  v 6 Integrin Act in a Common Pathway to Suppress Pancreatic Cancer Progression

(2012) A. F. Hezel et al.   CANCER RESEARCH

EMT and Dissemination Precede Pancreatic Tumor Formation

(2012) Andrew D. Rhim et al.   CELL

Translational Therapeutic Opportunities in Ductal Adenocarcinoma of the Pancreas

(2012) M. Hidalgo et al.   CLINICAL CANCER RESEARCH

Concurrent PEDF deficiency and Kras mutation induce invasive pancreatic cancer and adipose-rich stroma in mice

(2012) Paul J Grippo et al.   GUT

The role of stroma in pancreatic cancer: diagnostic and therapeutic implications

(2012) Mert Erkan et al.   Nature Reviews Gastroenterology & Hepatology

Endothelial SurfaceN-Glycans Mediate Monocyte Adhesion and Are Targets for Anti-inflammatory Effects of Peroxisome Proliferator-activated Receptor γ Ligands

(2011) Balu K. Chacko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pancreatic cancer

(2011) Audrey Vincent et al.   LANCET

Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry

(2011) Warwick B Dunn et al.   Nature Protocols

Role of endogenous cholecystokinin on growth of human pancreatic cancer

(2010) Smith   INTERNATIONAL JOURNAL OF ONCOLOGY

Lipid droplet-associated PAT-proteins show frequent and differential expression in neoplastic steatogenesis

(2010) Beate K Straub et al.   MODERN PATHOLOGY

EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer

(2010) A Singh et al.   ONCOGENE

TGF-β and fibrosis in different organs — molecular pathway imprints

(2009) Dirk Pohlers et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Bidirectional Transport of Amino Acids Regulates mTOR and Autophagy

(2009) Paul Nicklin et al.   CELL

Glycosylation in immune cell trafficking

(2009) Markus Sperandio et al.   IMMUNOLOGICAL REVIEWS

mTOR signaling at a glance

(2009) M. Laplante et al.   JOURNAL OF CELL SCIENCE

MetaboAnalyst: a web server for metabolomic data analysis and interpretation

(2009) J. Xia et al.   NUCLEIC ACIDS RESEARCH

Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer

(2009) K. P. Olive et al.   SCIENCE

Amino acid regulation of TOR complex 1

(2008) Joseph Avruch et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM