Effects of transcranial ultrasound stimulation pulsed at 40 Hz on Aβ plaques and brain rhythms in 5×FAD mice

A pilot clinical study of low-intensity transcranial focused ultrasound in Alzheimer’s disease

(2021) Hyeonseok Jeong et al.   Ultrasonography

Prevalence of cerebral amyloid angiopathy: A systematic review and meta‐analysis

(2021) Lieke Jäkel et al.   Alzheimers & Dementia

Can we learn lessons from the FDA’s approval of aducanumab?

(2021) Kathy Y. Liu et al.   Nature Reviews Neurology

Effective Ultrasonic Stimulation in Human Peripheral Nervous System

(2021) Thomas Riis et al.   IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

Extensive frontal focused ultrasound mediated blood–brain barrier opening for the treatment of Alzheimer’s disease: a proof-of-concept study

(2021) So Hee Park et al.   Translational Neurodegeneration

Transcranial focused ultrasound, pulsed at 40 Hz, activates microglia acutely and reduces Aβ load chronically, as demonstrated in vivo

(2020) M.S. Bobola et al.   Brain Stimulation

Applications of focused ultrasound in the brain: from thermoablation to drug delivery

(2020) Ying Meng et al.   Nature Reviews Neurology

Improvement of glymphatic–lymphatic drainage of beta-amyloid by focused ultrasound in Alzheimer’s disease model

(2020) Youngsun Lee et al.   Scientific Reports

Modulation of β-Amyloid Fibril Formation in Alzheimer’s Disease by Microglia and Infection

(2020) Madeleine R. Brown et al.   Frontiers in Molecular Neuroscience

Priming of microglia with IFN-γ slows neuronal gamma oscillations in situ

(2019) Thuy-Truc Ta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multi-sensory Gamma Stimulation Ameliorates Alzheimer’s-Associated Pathology and Improves Cognition

(2019) Anthony J. Martorell et al.   CELL

Transcranial Low-Intensity Pulsed Ultrasound Modulates Structural and Functional Synaptic Plasticity in Rat Hippocampus

(2019) Xiaowei Huang et al.   IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL

Gamma Entrainment Binds Higher-Order Brain Regions and Offers Neuroprotection

(2019) Chinnakkaruppan Adaikkan et al.   NEURON

Transcranial Pulse Stimulation with Ultrasound in Alzheimer's Disease—A New Navigated Focal Brain Therapy

(2019) Roland Beisteiner et al.   Advanced Science

Whole-brain low-intensity pulsed ultrasound therapy markedly improves cognitive dysfunctions in mouse models of dementia - Crucial roles of endothelial nitric oxide synthase

(2018) Kumiko Eguchi et al.   Brain Stimulation

Gamma oscillations in cognitive disorders

(2018) Alexandra J Mably et al.   CURRENT OPINION IN NEUROBIOLOGY

Why do trials for Alzheimer’s disease drugs keep failing? A discontinued drug perspective for 2010-2015

(2017) Dev Mehta et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Quantitative microglia analyses reveal diverse morphologic responses in the rat cortex after diffuse brain injury

(2017) Helena Morrison et al.   Scientific Reports

Failed Alzheimer’s trial does not kill leading theory of disease

(2016) Alison Abbott et al.   NATURE

Gamma frequency entrainment attenuates amyloid load and modifies microglia

(2016) Hannah F. Iaccarino et al.   NATURE

Apolipoprotein E4 Causes Age-Dependent Disruption of Slow Gamma Oscillations during Hippocampal Sharp-Wave Ripples

(2016) Anna K. Gillespie et al.   NEURON

Effect of noninvasive focused ultrasound stimulation on gamma oscillations in rat hippocampus

(2016) Yi Yuan et al.   NEUROREPORT

Frequency Dependence of Ultrasound Neurostimulation in the Mouse Brain

(2016) Patrick Peiyong Ye et al.   ULTRASOUND IN MEDICINE AND BIOLOGY

Innate immunity in Alzheimer's disease

(2015) Michael T Heneka et al.   NATURE IMMUNOLOGY

Alzheimer's disease

(2015) Colin L. Masters et al.   Nature Reviews Disease Primers

GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease

(2014) Seonmi Jo et al.   NATURE MEDICINE

2013 Alzheimer's disease facts and figures

(2013)   Alzheimers & Dementia

IFN-  Production by Amyloid  -Specific Th1 Cells Promotes Microglial Activation and Increases Plaque Burden in a Mouse Model of Alzheimer's Disease

(2013) T. C. Browne et al.   JOURNAL OF IMMUNOLOGY

Inhibitory Interneuron Deficit Links Altered Network Activity and Cognitive Dysfunction in Alzheimer Model

(2012) Laure Verret et al.   CELL

A critical role for NMDA receptors in parvalbumin interneurons for gamma rhythm induction and behavior

(2011) M Carlén et al.   MOLECULAR PSYCHIATRY

Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders

(2011) Berislav V. Zlokovic   NATURE REVIEWS NEUROSCIENCE

Soluble amyloid  -protein dimers isolated from Alzheimer cortex directly induce Tau hyperphosphorylation and neuritic degeneration

(2011) M. Jin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Parvalbumin neurons and gamma rhythms enhance cortical circuit performance

(2009) Vikaas S. Sohal et al.   NATURE

Amyloid β-Protein Toxicity and the Pathogenesis of Alzheimer Disease

(2008) Bruce A. Yankner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloid-β causes memory impairment by disturbing the JAK2/STAT3 axis in hippocampal neurons

(2008) T Chiba et al.   MOLECULAR PSYCHIATRY

Rapid appearance and local toxicity of amyloid-β plaques in a mouse model of Alzheimer’s disease

(2008) Melanie Meyer-Luehmann et al.   NATURE