Potassium channel-driven bioelectric signalling regulates metastasis in triple-negative breast cancer

Particle tracking microrheology of cancer cells in living subjects

(2020) Pei-Hsun Wu et al.   Materials Today

Novel Blocker of Onco SK3 Channels Derived from Scorpion Toxin Tamapin and Active against Migration of Cancer Cells

(2020) Marlen Mayorga-Flores et al.   ACS Medicinal Chemistry Letters

The Functional Role of Voltage-Gated Sodium Channel Nav1.5 in Metastatic Breast Cancer

(2020) Qianxuan Luo et al.   Frontiers in Pharmacology

Low dose amiodarone reduces tumor growth and angiogenesis

(2020) Eliana Steinberg et al.   Scientific Reports

Potassium channel activity controls breast cancer metastasis by affecting β-catenin signaling

(2019) Eun-Kyoung Breuer et al.   Cell Death & Disease

Interactions between cadherin-11 and platelet-derived growth factor receptor-alpha signaling link cell adhesion and proliferation

(2019) Bhanupriya Madarampalli et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

A microfluidic assay for the quantification of the metastatic propensity of breast cancer specimens

(2019) Christopher L. Yankaskas et al.   Nature Biomedical Engineering

Monospecific antibody targeting of CDH11 inhibits epithelial-to-mesenchymal transition and represses cancer stem cell-like phenotype by up-regulating miR-335 in metastatic breast cancer, in vitro and in vivo

(2019) Jia-Hong Chen et al.   BMC CANCER

Update on triple‐negative breast cancer disparities for the United States: A population‐based study from the United States Cancer Statistics database, 2010 through 2014

(2019) Lia C. Scott et al.   CANCER

Improved Survival in Hepatocellular Carcinoma Patients with Cardiac Arrhythmia by Amiodarone Treatment through Autophagy

(2019) Huang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Voltage‐dependent activation of Rac1 by Na v 1.5 channels promotes cell migration

(2019) Ming Yang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Toward Decoding Bioelectric Events in Xenopus Embryogenesis: New Methodology for Tracking Interplay Between Calcium and Resting Potentials In Vivo

(2019) Patrick McMillen et al.   JOURNAL OF MOLECULAR BIOLOGY

In Vivo Evidence for Voltage-Gated Sodium Channel Expression in Carcinomas and Potentiation of Metastasis

(2019) Mustafa B. A. Djamgoz et al.   Cancers

Sodium Channel Nav1.5 Controls Epithelial-to-Mesenchymal Transition and Invasiveness in Breast Cancer Cells Through its Regulation by the Salt-Inducible Kinase-1

(2019) Frédéric Gradek et al.   Scientific Reports

Amiodarone, a multi-channel blocker, enhances anticonvulsive effect of carbamazepine in the mouse maximal electroshock model

(2018) Monika Banach et al.   EPILEPSY RESEARCH

Ion Channels in Cancer: Are Cancer Hallmarks Oncochannelopathies?

(2018) Natalia Prevarskaya et al.   PHYSIOLOGICAL REVIEWS

Piezo2 channel regulates RhoA and actin cytoskeleton to promote cell mechanobiological responses

(2018) Carlos Pardo-Pastor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Involvement of AMP-activated Protein Kinase (AMPK) in Regulation of Cell Membrane Potential in a Gastric Cancer Cell Line

(2018) Lin Zhu et al.   Scientific Reports

Electrical Characterization of Normal and Cancer Cells

(2018) Mahmoud Al Ahmad et al.   IEEE Access

Evaluation of the anticancer and anti-metastasis effects of novel synthetic sodium channel blockers in prostate cancer cells in vitro and in vivo

(2018) Jiajia Wang et al.   PROSTATE

Interactions between amiodarone and the hERG potassium channel pore determined with mutagenesis and in silico docking

(2016) Yihong Zhang et al.   BIOCHEMICAL PHARMACOLOGY

Pharmacological targeting of ion channels for cancer therapy: In vivo evidences

(2016) Luigi Leanza et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Bioelectric signalling via potassium channels: a mechanism for craniofacial dysmorphogenesis in KCNJ2-associated Andersen-Tawil Syndrome

(2016) Dany Spencer Adams et al.   JOURNAL OF PHYSIOLOGY-LONDON

The class III anti-arrhythmic agent, amiodarone, inhibits voltage-dependent K+ channels in rabbit coronary arterial smooth muscle cells

(2016) Hongliang Li et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Cadherin-11 expression is upregulated in invasive human breast cancer

(2016) Kamil Pohlodek et al.   Oncology Letters

Cadherin-11 localizes to focal adhesions and promotes cell–substrate adhesion

(2016) Rahul P. Langhe et al.   Nature Communications

Use of genetically encoded, light-gated ion translocators to control tumorigenesis

(2016) Brook T. Chernet et al.   Oncotarget

SARTools: A DESeq2- and EdgeR-Based R Pipeline for Comprehensive Differential Analysis of RNA-Seq Data

(2016) Hugo Varet et al.   PLoS One

Targeting ion channels for cancer therapy by repurposing the approved drugs

(2015) Vijay Pralhad Kale et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Endogenous Gradients of Resting Potential Instructively Pattern Embryonic Neural Tissue via Notch Signaling and Regulation of Proliferation

(2015) V. P. Pai et al.   JOURNAL OF NEUROSCIENCE

EAG2 potassium channel with evolutionarily conserved function as a brain tumor target

(2015) Xi Huang et al.   NATURE NEUROSCIENCE

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

Targeting potassium channels in cancer

(2014) Xi Huang et al.   JOURNAL OF CELL BIOLOGY

Potassium channels in cell cycle and cell proliferation

(2014) D. Urrego et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Pivotal Role of the Lipid Raft SK3-Orai1 Complex in Human Cancer Cell Migration and Bone Metastases

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KCa3.1 channels are involved in the infiltrative behavior of glioblastoma in vivo

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Therapeutic potential for phenytoin: targeting Nav1.5 sodium channels to reduce migration and invasion in metastatic breast cancer

(2012) Ming Yang et al.   BREAST CANCER RESEARCH AND TREATMENT

Role of Ion Channels and Transporters in Cell Migration

(2012) Albrecht Schwab et al.   PHYSIOLOGICAL REVIEWS

The Crest Phenotype in Chicken Is Associated with Ectopic Expression of HOXC8 in Cranial Skin

(2012) Yanqiang Wang et al.   PLoS One

Bioelectric controls of cell proliferation: Ion channels, membrane voltage and the cell cycle

(2011) Douglas J. Blackiston et al.   CELL CYCLE

Randomised controlled trial of lipiodol transarterial chemoembolisation with or without amiodarone for unresectable hepatocellular carcinoma

(2011) Mathieu Boulin et al.   DIGESTIVE AND LIVER DISEASE

Mena invasive (MenaINV) promotes multicellular streaming motility and transendothelial migration in a mouse model of breast cancer

(2011) E. T. Roussos et al.   JOURNAL OF CELL SCIENCE

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(2009) M. D. Robinson et al.   BIOINFORMATICS

KCa2.3 channel-dependent hyperpolarization increases melanoma cell motility

(2009) Aurelie Chantome et al.   EXPERIMENTAL CELL RESEARCH

Hyperpolarization of the plasma membrane potential provokes reorganization of the actin cytoskeleton and increases the stability of adherens junctions in bovine corneal endothelial cells in culture

(2009) Verónica Nin et al.   CELL MOTILITY AND THE CYTOSKELETON

Electrolytes and Trace Elements in Human Breast Cyst Fluid

(2008) Ali Rıza Şişman et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Pattern of metastatic spread in triple-negative breast cancer

(2008) Rebecca Dent et al.   BREAST CANCER RESEARCH AND TREATMENT

Novel Amiodarone−Doxorubicin Cocktail Liposomes Enhance Doxorubicin Retention and Cytotoxicity in DU145 Human Prostate Carcinoma Cells

(2008) Theodossis A. Theodossiou et al.   JOURNAL OF MEDICINAL CHEMISTRY