Dysregulation of cholesterol homeostasis in human lung cancer tissue and tumour-associated macrophages

Accurate quantification of lipid species affected by isobaric overlap in Fourier-Transform mass spectrometry

(2021) Marcus Höring et al.   JOURNAL OF LIPID RESEARCH

Targeting the PI3K/Akt/mTOR pathway in non‐small cell lung cancer (NSCLC)

(2020) Aaron C. Tan   Thoracic Cancer

Thioholgamide A, a New Anti-Proliferative Anti-Tumor Agent, Modulates Macrophage Polarization and Metabolism

(2020) Charlotte Dahlem et al.   Cancers

Spatial Density and Distribution of Tumor-Associated Macrophages Predict Survival in Non-Small-Cell Lung Carcinoma

(2020) Xiang Zheng et al.   CANCER RESEARCH

Reprogramming of tumor-associated macrophages by targeting β-catenin/FOSL2/ARID5A signaling: A potential treatment of lung cancer

(2020) Poonam Sarode et al.   Science Advances

Statin use and prognosis of lung cancer: a systematic review and meta-analysis of observational studies and randomized controlled trials

(2019) Dao-Kui Xia et al.   Drug Design Development and Therapy

Membrane Cholesterol Efflux Drives Tumor-Associated Macrophage Reprogramming and Tumor Progression

(2019) Pieter Goossens et al.   Cell Metabolism

Quantification of Cholesterol and Cholesteryl Ester by Direct Flow Injection High-Resolution Fourier Transform Mass Spectrometry Utilizing Species-Specific Response Factors

(2019) Marcus Höring et al.   ANALYTICAL CHEMISTRY

Membrane Cholesterol Regulates Macrophage Plasticity in Cancer

(2019) Antonio Sica et al.   Cell Metabolism

Macrophages and Metabolism in the Tumor Microenvironment

(2019) Ilio Vitale et al.   Cell Metabolism

ShinyGO: a graphical gene-set enrichment tool for animals and plants

(2019) Steven Xijin Ge et al.   BIOINFORMATICS

Clinical lipidomics in understanding of lung cancer: Opportunity and challenge

(2019) Linlin Zhang et al.   CANCER LETTERS

Macrophage plasticity, polarization, and function in health and disease

(2018) Abbas Shapouri-Moghaddam et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

PANTHER version 14: more genomes, a new PANTHER GO-slim and improvements in enrichment analysis tools

(2018) Huaiyu Mi et al.   NUCLEIC ACIDS RESEARCH

Tumor-associated myeloid cells: new understandings on their metabolic regulation and their influence in cancer immunotherapy

(2017) Chiara Porta et al.   FEBS Journal

Hepatic interleukin-6 production is maintained during endotoxin tolerance and facilitates lipid accumulation

(2017) Anna Dembek et al.   IMMUNOBIOLOGY

Salmon provides fast and bias-aware quantification of transcript expression

(2017) Rob Patro et al.   NATURE METHODS

Lipidomes of lung cancer and tumour-free lung tissues reveal distinct molecular signatures for cancer differentiation, age, inflammation, and pulmonary emphysema

(2017) Lars F. Eggers et al.   Scientific Reports

Macrophages, Inflammation, and Lung Cancer

(2016) Emma M. Conway et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

A Breakthrough: Macrophage-Directed Cancer Immunotherapy

(2016) C. D. Mills et al.   CANCER RESEARCH

ATR-101, a Selective and Potent Inhibitor of Acyl-CoA Acyltransferase 1, Induces Apoptosis in H295R Adrenocortical Cells and in the Adrenal Cortex of Dogs

(2016) Christopher R. LaPensee et al.   ENDOCRINOLOGY

Role of tumor-associated macrophages in human malignancies: friend or foe?

(2016) Motohiro Takeya et al.   PATHOLOGY INTERNATIONAL

Transcriptional and metabolic reprogramming induce an inflammatory phenotype in non-medullary thyroid carcinoma-induced macrophages

(2016) Rob J. W. Arts et al.   OncoImmunology

Macrophage polarization in pathology

(2015) Antonio Sica et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Non-small cell lung cancer is characterized by dramatic changes in phospholipid profiles

(2015) Eyra Marien et al.   INTERNATIONAL JOURNAL OF CANCER

The prognostic landscape of genes and infiltrating immune cells across human cancers

(2015) Andrew J Gentles et al.   NATURE MEDICINE

Cholesterol uptake disruption, in association with chemotherapy, is a promising combined metabolic therapy for pancreatic adenocarcinoma

(2015) Fabienne Guillaumond et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The cholesterol transporter ABCG1 links cholesterol homeostasis and tumour immunity

(2015) Duygu Sag et al.   Nature Communications

LXRs link metabolism to inflammation through Abca1-dependent regulation of membrane composition and TLR signaling

(2015) Ayaka Ito et al.   eLife

Role of Chemokines in Non-Small Cell Lung Cancer: Angiogenesis and Inflammation

(2015) Selma Rivas-Fuentes et al.   Journal of Cancer

Inhibition of Fatty Acid Oxidation Modulates Immunosuppressive Functions of Myeloid-Derived Suppressor Cells and Enhances Cancer Therapies

(2015) F. Hossain et al.   Cancer Immunology Research

M2 polarization enhances silica nanoparticle uptake by macrophages

(2015) Jessica Hoppstädter et al.   Frontiers in Pharmacology

Opposite Effects of M1 and M2 Macrophage Subtypes on Lung Cancer Progression

(2015) Ang Yuan et al.   Scientific Reports

Fatty acid oxidation is dispensable for human macrophage IL-4-induced polarization

(2014) Dmitry Namgaladze et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Normalization of RNA-seq data using factor analysis of control genes or samples

(2014) Davide Risso et al.   NATURE BIOTECHNOLOGY

Molecular Mechanisms That Influence the Macrophage M1–M2 Polarization Balance

(2014) Nan Wang et al.   Frontiers in Immunology

Shorthand notation for lipid structures derived from mass spectrometry

(2013) Gerhard Liebisch et al.   JOURNAL OF LIPID RESEARCH

Analysis of Lipid Experiments (ALEX): A Software Framework for Analysis of High-Resolution Shotgun Lipidomics Data

(2013) Peter Husen et al.   PLoS One

Glucocorticoid-induced leucine zipper is downregulated in human alveolar macrophages upon Toll-like receptor activation

(2012) Jessica Hoppstädter et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

M2-Polarized tumor-associated macrophages are associated with poor prognoses resulting from accelerated lymphangiogenesis in lung adenocarcinoma

(2011) Bicheng Zhang et al.   Clinics

The M1 form of tumor-associated macrophages in non-small cell lung cancer is positively associated with survival time

(2010) Junliang Ma et al.   BMC CANCER

Stromal Macrophage Expressing CD204 is Associated with Tumor Aggressiveness in Lung Adenocarcinoma

(2010) Yoichi Ohtaki et al.   Journal of Thoracic Oncology

ATP-binding cassette transporter hallmarks tissue macrophages and modulates cytokine-triggered polarization programs

(2009) Lydie C. Pradel et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Macrophages within NSCLC tumour islets are predominantly of a cytotoxic M1 phenotype associated with extended survival

(2009) C. M. Ohri et al.   EUROPEAN RESPIRATORY JOURNAL

Lipid extraction by methyl-tert-butyl ether for high-throughput lipidomics

(2008) Vitali Matyash et al.   JOURNAL OF LIPID RESEARCH