Synovial tissue from sites of joint pain in knee osteoarthritis patients exhibits a differential phenotype with distinct fibroblast subsets

Distinct fibroblast subsets drive inflammation and damage in arthritis

(2019) Adam P. Croft et al.   NATURE

Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry

(2019) Fan Zhang et al.   NATURE IMMUNOLOGY

Pharmacological Blockade of Spinal CXCL3/CXCR2 Signaling by NVP CXCR2 20, a Selective CXCR2 Antagonist, Reduces Neuropathic Pain Following Peripheral Nerve Injury

(2019) Anna Piotrowska et al.   Frontiers in Immunology

Obese osteoarthritis patients exhibit an inflammatory synovial fibroblast phenotype, which is regulated by the long non coding RNA MALAT1

(2019) Dominika E Nanus et al.   Arthritis & Rheumatology

Expression of the Atypical Chemokine Receptor ACKR4 Identifies a Novel Population of Intestinal Submucosal Fibroblasts That Preferentially Expresses Endothelial Cell Regulators

(2018) Carolyn A. Thomson et al.   JOURNAL OF IMMUNOLOGY

The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2018 update

(2018) Enis Afgan et al.   NUCLEIC ACIDS RESEARCH

Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis

(2018) Fumitaka Mizoguchi et al.   Nature Communications

Circulating and Synovial Fluid Heat Shock Protein 70 Are Correlated with Severity in Knee Osteoarthritis

(2018) Srihatach Ngarmukos et al.   Cartilage

IL-6 secretion in osteoarthritis patients is mediated by chondrocyte-synovial fibroblast cross-talk and is enhanced by obesity

(2017) Mark J. Pearson et al.   Scientific Reports

Association of Pain in Knee Osteoarthritis With Distinct Patterns of Synovitis

(2015) B. J. E. de Lange-Brokaar et al.   Arthritis & Rheumatology

Sulf1 and Sulf2 Differentially Modulate Heparan Sulfate Proteoglycan Sulfation during Postnatal Cerebellum Development: Evidence for Neuroprotective and Neurite Outgrowth Promoting Functions

(2015) Ina Kalus et al.   PLoS One

Neuritin, A Neurotrophic Factor in Nervous System Physiology

(2014) S. Zhou et al.   CURRENT MEDICINAL CHEMISTRY

Osteoarthritis joint pain: The cytokine connection

(2014) Rachel E. Miller et al.   CYTOKINE

Chemokine CXCL1 enhances inflammatory pain and increases NMDA receptor activity and COX-2 expression in spinal cord neurons via activation of CXCR2

(2014) De-Li Cao et al.   EXPERIMENTAL NEUROLOGY

The hallmarks of osteoarthritis and the potential to develop personalised disease-modifying pharmacological therapeutics

(2014) D.P. Tonge et al.   OSTEOARTHRITIS AND CARTILAGE

The epidemiology and impact of pain in osteoarthritis

(2013) T. Neogi   OSTEOARTHRITIS AND CARTILAGE

Associations between proinflammatory cytokines in the synovial fluid and radiographic grading and pain-related scores in 47 consecutive patients with osteoarthritis of the knee

(2011) Sumihisa Orita et al.   BMC MUSCULOSKELETAL DISORDERS

KCa1.1 Potassium Channels Regulate Key Proinflammatory and Invasive Properties of Fibroblast-like Synoviocytes in Rheumatoid Arthritis

(2011) Xueyou Hu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Relation of synovitis to knee pain using contrast-enhanced MRIs

(2010) K. Baker et al.   ANNALS OF THE RHEUMATIC DISEASES

Assessment of synovitis with contrast-enhanced MRI using a whole-joint semiquantitative scoring system in people with, or at high risk of, knee osteoarthritis: the MOST study

(2010) A. Guermazi et al.   ANNALS OF THE RHEUMATIC DISEASES

Differential effects of locally and systemically administered soluble glycoprotein 130 on pain and inflammation in experimental arthritis

(2010) Michael K Boettger et al.   ARTHRITIS RESEARCH & THERAPY

Emerging roles of serine proteinases in tissue turnover in arthritis

(2008) J. M. Milner et al.   ARTHRITIS AND RHEUMATISM