IL-6 secretion in osteoarthritis patients is mediated by chondrocyte-synovial fibroblast cross-talk and is enhanced by obesity

Adipokines in bone disease

(2016) Elena Neumann et al.   Nature Reviews Rheumatology

Associations of surgical and nonsurgical weight loss with knee musculature: a cohort study of obese adults

(2016) Andrew J. Teichtahl et al.   Surgery for Obesity and Related Diseases

Unicompartmental and bicompartmental knee osteoarthritis show different patterns of mononuclear cell infiltration and cytokine release in the affected joints

(2015) B. Moradi et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Obesity Is Common in Axial Spondyloarthritis and Is Associated with Poor Clinical Outcome

(2015) Fiona Maas et al.   JOURNAL OF RHEUMATOLOGY

Differential expression of interleukin-17 and interleukin-22 in inflamed and non-inflamed synovium from osteoarthritis patients

(2015) C. Deligne et al.   OSTEOARTHRITIS AND CARTILAGE

Leptin induces ADAMTS-4, ADAMTS-5, and ADAMTS-9 genes expression by mitogen-activated protein kinases and NF-ĸB signaling pathways in human chondrocytes

(2014) Kursat Oguz Yaykasli et al.   CELL BIOLOGY INTERNATIONAL

The hallmarks of osteoarthritis and the potential to develop personalised disease-modifying pharmacological therapeutics

(2014) D.P. Tonge et al.   OSTEOARTHRITIS AND CARTILAGE

Adipokines, Metabolic Syndrome and Rheumatic Diseases

(2014) Vanessa Abella et al.   Journal of Immunology Research

NAMPT (visfatin), a direct target of hypoxia-inducible factor-2α, is an essential catabolic regulator of osteoarthritis

(2013) Siyoung Yang et al.   ANNALS OF THE RHEUMATIC DISEASES

Inflammatory Mediators: Tracing Links Between Obesity and Osteoarthritis

(2012) Muhammad Farooq Rai et al.   CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION

Serum adipokines in osteoarthritis; comparison with controls and relationship with local parameters of synovial inflammation and cartilage damage

(2012) T.N. de Boer et al.   OSTEOARTHRITIS AND CARTILAGE

Obesity and psoriatic arthritis: from pathogenesis to clinical outcome and management

(2012) A. Russolillo et al.   RHEUMATOLOGY

Leptin produced by joint white adipose tissue induces cartilage degradation via upregulation and activation of matrix metalloproteinases

(2011) Wang Hui et al.   ANNALS OF THE RHEUMATIC DISEASES

Temporal relationship between serum adipokines, biomarkers of bone and cartilage turnover, and cartilage volume loss in a population with clinical knee osteoarthritis

(2011) Patricia A. Berry et al.   ARTHRITIS AND RHEUMATISM

Inhibition of TNF-induced IL-6 by the TWEAK-Fn14 interaction in rheumatoid arthritis fibroblast like synoviocytes

(2011) Jiro Yamana et al.   CELLULAR IMMUNOLOGY

Notch Signaling Mediates TNF-α-Induced IL-6 Production in Cultured Fibroblast-Like Synoviocytes from Rheumatoid Arthritis

(2011) Zhijun Jiao et al.   Clinical & Developmental Immunology

Metabolic Factors in Obesity

(2011) N. Brito et al.   JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM

Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions

(2011) Yeonseok Chung et al.   NATURE MEDICINE

Lifetime body mass index, other anthropometric measures of obesity and risk of knee or hip osteoarthritis in the GOAL case-control study

(2010) K.L. Holliday et al.   OSTEOARTHRITIS AND CARTILAGE

Cell culture and passaging alters gene expression pattern and proliferation rate in rheumatoid arthritis synovial fibroblasts

(2010) Elena Neumann et al.   ARTHRITIS RESEARCH & THERAPY

IL-6 trans-signalling directly induces RANKL on fibroblast-like synovial cells and is involved in RANKL induction by TNF-  and IL-17

(2008) M. Hashizume et al.   RHEUMATOLOGY