Integrator enforces the fidelity of transcriptional termination at protein-coding genes
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Integrator enforces the fidelity of transcriptional termination at protein-coding genes
Authors
Keywords
-
Journal
Science Advances
Volume 7, Issue 45, Pages -
Publisher
American Association for the Advancement of Science (AAAS)
Online
2021-11-04
DOI
10.1126/sciadv.abe3393
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Integrator is a genome-wide attenuator of non-productive transcription
- (2021) Søren Lykke-Andersen et al. MOLECULAR CELL
- Hyperosmotic stress alters the RNA polymerase II interactome and induces readthrough transcription despite widespread transcriptional repression
- (2021) Nicolle A. Rosa-Mercado et al. MOLECULAR CELL
- The Human Integrator Complex Facilitates Transcriptional Elongation by Endonucleolytic Cleavage of Nascent Transcripts
- (2020) Felipe Beckedorff et al. Cell Reports
- Integrator restrains paraspeckles assembly by promoting isoform switching of the lncRNA NEAT1
- (2020) Jasmine Barra et al. Science Advances
- The Integrator complex cleaves nascent mRNAs to attenuate transcription
- (2019) Deirdre C. Tatomer et al. GENES & DEVELOPMENT
- The Integrator Complex Attenuates Promoter-Proximal Transcription at Protein-Coding Genes
- (2019) Nathan D. Elrod et al. MOLECULAR CELL
- Tyrosine-1 of RNA Polymerase II CTD Controls Global Termination of Gene Transcription in Mammals
- (2018) Nilay Shah et al. MOLECULAR CELL
- Integrator subunit 4 is a ‘Symplekin-like’ scaffold that associates with INTS9/11 to form the Integrator cleavage module
- (2018) Todd R Albrecht et al. NUCLEIC ACIDS RESEARCH
- Two distinct transcription termination modes dictated by promoters
- (2017) Takashi S. Miki et al. GENES & DEVELOPMENT
- Integrator orchestrates RAS/ERK1/2 signaling transcriptional programs
- (2017) Jingyin Yue et al. GENES & DEVELOPMENT
- Comparative analysis reveals genomic features of stress-induced transcriptional readthrough
- (2017) Anna Vilborg et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Human TFIIH Kinase CDK7 Regulates Transcription-Associated Chromatin Modifications
- (2017) Christopher C. Ebmeier et al. Cell Reports
- P-TEFb regulation of transcription termination factor Xrn2 revealed by a chemical genetic screen for Cdk9 substrates
- (2016) Miriam Sansó et al. GENES & DEVELOPMENT
- Robust transcriptome-wide discovery of RNA-binding protein binding sites with enhanced CLIP (eCLIP)
- (2016) Eric L Van Nostrand et al. NATURE METHODS
- Base-pair-resolution genome-wide mapping of active RNA polymerases using precision nuclear run-on (PRO-seq)
- (2016) Dig Bijay Mahat et al. Nature Protocols
- The pol II CTD: new twists in the tail
- (2016) Justyna Zaborowska et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- R-loopDB: a database for R-loop forming sequences (RLFS) and R-loops
- (2016) Piroon Jenjaroenpun et al. NUCLEIC ACIDS RESEARCH
- deepTools2: a next generation web server for deep-sequencing data analysis
- (2016) Fidel Ramírez et al. NUCLEIC ACIDS RESEARCH
- Readthrough transcription: How are DoGs made and what do they do?
- (2016) Anna Vilborg et al. RNA Biology
- Transcriptional termination in mammals: Stopping the RNA polymerase II juggernaut
- (2016) N. J. Proudfoot SCIENCE
- The pol II CTD: new twists in the tail
- (2016) Justyna Zaborowska et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The Integrator complex controls the termination of transcription at diverse classes of gene targets
- (2015) Jeffrey R Skaar et al. CELL RESEARCH
- The host Integrator complex acts in transcription-independent maturation of herpesvirus microRNA 3′ ends
- (2015) Mingyi Xie et al. GENES & DEVELOPMENT
- Poly(A) Signal-Dependent Transcription Termination Occurs through a Conformational Change Mechanism that Does Not Require Cleavage at the Poly(A) Site
- (2015) Huimin Zhang et al. MOLECULAR CELL
- Effects of Transcription Elongation Rate and Xrn2 Exonuclease Activity on RNA Polymerase II Termination Suggest Widespread Kinetic Competition
- (2015) Nova Fong et al. MOLECULAR CELL
- Widespread Inducible Transcription Downstream of Human Genes
- (2015) Anna Vilborg et al. MOLECULAR CELL
- Integrator mediates the biogenesis of enhancer RNAs
- (2015) Fan Lai et al. NATURE
- Getting up to speed with transcription elongation by RNA polymerase II
- (2015) Iris Jonkers et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Integrator: surprisingly diverse functions in gene expression
- (2015) David Baillat et al. TRENDS IN BIOCHEMICAL SCIENCES
- Widespread disruption of host transcription termination in HSV-1 infection
- (2015) Andrzej J. Rutkowski et al. Nature Communications
- Pervasive transcription read-through promotes aberrant expression of oncogenes and RNA chimeras in renal carcinoma
- (2015) Ana R Grosso et al. eLife
- Trimmomatic: a flexible trimmer for Illumina sequence data
- (2014) Anthony M. Bolger et al. BIOINFORMATICS
- Poly(A) polymerase (PAP) diversity in gene expression - Star-PAP vs canonical PAP
- (2014) Rakesh S. Laishram FEBS LETTERS
- 3' end formation of pre-mRNA and phosphorylation of Ser2 on the RNA polymerase II CTD are reciprocally coupled in human cells
- (2014) L. Davidson et al. GENES & DEVELOPMENT
- Integrator Regulates Transcriptional Initiation and Pause Release following Activation
- (2014) Alessandro Gardini et al. MOLECULAR CELL
- GC skew at the 5' and 3' ends of human genes links R-loop formation to epigenetic regulation and transcription termination
- (2013) P. A. Ginno et al. GENOME RESEARCH
- Alternative cleavage and polyadenylation: the long and short of it
- (2013) Bin Tian et al. TRENDS IN BIOCHEMICAL SCIENCES
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- The RNA polymerase II CTD coordinates transcription and RNA processing
- (2012) J.-P. Hsin et al. GENES & DEVELOPMENT
- RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome
- (2011) Bo Li et al. BMC BIOINFORMATICS
- Ending the message: poly(A) signals then and now
- (2011) N. J. Proudfoot GENES & DEVELOPMENT
- Transcriptional Activators Enhance Polyadenylation of mRNA Precursors
- (2011) Takashi Nagaike et al. MOLECULAR CELL
- Pre-mRNA splicing is a determinant of histone H3K36 methylation
- (2011) S. Kim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- BEDTools: a flexible suite of utilities for comparing genomic features
- (2010) Aaron R. Quinlan et al. BIOINFORMATICS
- The Integrator Complex Recognizes a New Double Mark on the RNA Polymerase II Carboxyl-terminal Domain
- (2010) Sylvain Egloff et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities
- (2010) Sven Heinz et al. MOLECULAR CELL
- Molecular Architecture of the Human Pre-mRNA 3′ Processing Complex
- (2009) Yongsheng Shi et al. MOLECULAR CELL
- Differential chromatin marking of introns and expressed exons by H3K36me3
- (2009) Paulina Kolasinska-Zwierz et al. NATURE GENETICS
- Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
- (2009) Ben Langmead et al. GENOME BIOLOGY
- The Vienna RNA Websuite
- (2008) A. R. Gruber et al. NUCLEIC ACIDS RESEARCH
- Nascent RNA Sequencing Reveals Widespread Pausing and Divergent Initiation at Human Promoters
- (2008) Leighton J. Core et al. SCIENCE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now