In vivo mRNA delivery to virus-specific T cells by light-induced ligand exchange of MHC class I antigen-presenting nanoparticles

In Vivo T Cell-Targeting Nanoparticle Drug Delivery Systems: Considerations for Rational Design

(2021) Paula M. Cevaal et al.   ACS Nano

Affinity-matured HLA class II dimers for robust staining of antigen-specific CD4+ T cells

(2021) Kenji Sugata et al.   NATURE BIOTECHNOLOGY

Engineered red blood cells as an off-the-shelf allogeneic anti-tumor therapeutic

(2021) Xuqing Zhang et al.   Nature Communications

Interfacing Biomaterials with Synthetic T Cell Immunity

(2021) Fang‐Yi Su et al.   Advanced Healthcare Materials

Delivery technologies for T cell gene editing: Applications in cancer immunotherapy

(2021) Ella S. Atsavapranee et al.   EBioMedicine

Functional HPV-specific PD-1+ stem-like CD8 T cells in head and neck cancer

(2021) Christiane S. Eberhardt et al.   NATURE

CUE-101, a Novel HPV16 E7-pHLA-IL-2-Fc Fusion Protein, Enhances Tumor Antigen Specific T Cell Activation for the Treatment of HPV16-Driven Malignancies

(2020) Steven N Quayle et al.   CLINICAL CANCER RESEARCH

Antibody-mediated delivery of viral epitopes to tumors harnesses CMV-specific T cells for cancer therapy

(2020) David G. Millar et al.   NATURE BIOTECHNOLOGY

High throughput pMHC-I tetramer library production using chaperone-mediated peptide exchange

(2020) Sarah A. Overall et al.   Nature Communications

The PD-1 Pathway Regulates Development and Function of Memory CD8+ T Cells following Respiratory Viral Infection

(2020) Kristen E. Pauken et al.   Cell Reports

In vivo detection of antigen-specific CD8+ T cells by immuno-positron emission tomography

(2020) Andrew W. Woodham et al.   NATURE METHODS

In vitro-transcribed antigen receptor mRNA nanocarriers for transient expression in circulating T cells in vivo

(2020) N. N. Parayath et al.   Nature Communications

DNA-Barcoded pMHC Tetramers for Detection of Single Antigen-Specific T Cells by Digital PCR

(2019) Shreyas N Dahotre et al.   ANALYTICAL CHEMISTRY

An artificial antigen-presenting cell delivering 11 immune molecules expands tumor antigen-specific CTLs in ex vivo and in vivo murine melanoma models

(2019) Lei Zhang et al.   Cancer Immunology Research

Quantification of epitope abundance reveals the effect of direct and cross-presentation on influenza CTL responses

(2019) Ting Wu et al.   Nature Communications

Sensitization of Tumors for Attack by Virus-Specific CD8+ T-Cells Through Antibody-Mediated Delivery of Immunogenic T-Cell Epitopes

(2019) Julian P. Sefrin et al.   Frontiers in Immunology

Antigen Identification for Orphan T Cell Receptors Expressed on Tumor-Infiltrating Lymphocytes

(2018) Marvin H. Gee et al.   CELL

A flexible MHC class I multimer loading system for large-scale detection of antigen-specific T cells

(2018) Jolien J. Luimstra et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A modular platform for targeted RNAi therapeutics

(2018) Ranit Kedmi et al.   Nature Nanotechnology

Individually addressable and dynamic DNA gates for multiplexed cell sorting

(2018) Shreyas N. Dahotre et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enhanced mRNA delivery into lymphocytes enabled by lipid-varied libraries of charge-altering releasable transporters

(2018) Colin J. McKinlay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Progress and challenges towards targeted delivery of cancer therapeutics

(2018) Daniel Rosenblum et al.   Nature Communications

Engineered mRNA-expressed antibodies prevent respiratory syncytial virus infection

(2018) Pooja Munnilal Tiwari et al.   Nature Communications

Cell specific delivery of modified mRNA expressing therapeutic proteins to leukocytes

(2018) Nuphar Veiga et al.   Nature Communications

Systematically benchmarking peptide-MHC binding predictors: From synthetic to naturally processed epitopes

(2018) Weilong Zhao et al.   PLoS Computational Biology

Site-selective orientated immobilization of antibodies and conjugates for immunodiagnostics development

(2017) Min Shen et al.   METHODS

In situ programming of leukaemia-specific T cells using synthetic DNA nanocarriers

(2017) Tyrel T. Smith et al.   Nature Nanotechnology

Peptide–MHC-based nanomedicines for autoimmunity function as T-cell receptor microclustering devices

(2017) Santiswarup Singha et al.   Nature Nanotechnology

T cell-targeting nanoparticles focus delivery of immunotherapy to improve antitumor immunity

(2017) Daniela Schmid et al.   Nature Communications

A Simple and Rapid Method for Quality Control of Major Histocompatibility Complex–Peptide Monomers by Flow Cytometry

(2017) P. Anoop Chandran et al.   Frontiers in Immunology

Expanding antigen-specific regulatory networks to treat autoimmunity

(2016) Xavier Clemente-Casares et al.   NATURE

Large-scale detection of antigen-specific T cells using peptide-MHC-I multimers labeled with DNA barcodes

(2016) Amalie Kai Bentzen et al.   NATURE BIOTECHNOLOGY

Systemic Gene Silencing in Primary T Lymphocytes Using Targeted Lipid Nanoparticles

(2015) Srinivas Ramishetti et al.   ACS Nano

Delivery of oligonucleotides with lipid nanoparticles

(2015) Yuhua Wang et al.   ADVANCED DRUG DELIVERY REVIEWS

Site-Specific Antibody–Drug Conjugates: The Nexus of Bioorthogonal Chemistry, Protein Engineering, and Drug Development

(2015) Paresh Agarwal et al.   BIOCONJUGATE CHEMISTRY

Conventional versus stealth lipid nanoparticles: Formulation and in vivo fate prediction through FRET monitoring

(2014) A.-L. Lainé et al.   JOURNAL OF CONTROLLED RELEASE

mRNA-based therapeutics — developing a new class of drugs

(2014) Ugur Sahin et al.   NATURE REVIEWS DRUG DISCOVERY

Dipeptides catalyze rapid peptide exchange on MHC class I molecules

(2014) Sunil Kumar Saini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modulation of Antigen-Specific T-Cells as Immune Therapy for Chronic Infectious Diseases and Cancer

(2014) Suling Li et al.   Frontiers in Immunology

In vivo targeting of adoptively transferred T-cells with antibody- and cytokine-conjugated liposomes

(2013) Yiran Zheng et al.   JOURNAL OF CONTROLLED RELEASE

Cooperativity Between CD8+ T Cells, Non-Neutralizing Antibodies, and Alveolar Macrophages Is Important for Heterosubtypic Influenza Virus Immunity

(2013) Brian J. Laidlaw et al.   PLoS Pathogens

Dissection of T-cell Antigen Specificity in Human Melanoma

(2012) R. S. Andersen et al.   CANCER RESEARCH

Microbiota regulates immune defense against respiratory tract influenza A virus infection

(2011) T. Ichinohe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Unexpectedly Large Polyclonal Repertoire of HPV-Specific T Cells Is Poised for Action in Patients with Cervical Cancer

(2010) Peggy J. de Vos van Steenwijk et al.   CANCER RESEARCH

Qualitatively Different Memory CD8+ T Cells Are Generated after Lymphocytic Choriomeningitis Virus and Influenza Virus Infections

(2010) S. N. Mueller et al.   JOURNAL OF IMMUNOLOGY

In vivo Administration of Artificial Antigen-Presenting Cells Activates Low-Avidity T Cells for Treatment of Cancer

(2009) S. Ugel et al.   CANCER RESEARCH

Modular Nucleic Acid Assembled p/MHC Microarrays for Multiplexed Sorting of Antigen-Specific T Cells

(2009) Gabriel A. Kwong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Immunization with Live Attenuated Influenza Viruses That Express Altered NS1 Proteins Results in Potent and Protective Memory CD8+ T-Cell Responses

(2009) S. N. Mueller et al.   JOURNAL OF VIROLOGY

Conditional MHC class I ligands and peptide exchange technology for the human MHC gene products HLA-A1, -A3, -A11, and -B7

(2008) A. H. Bakker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Discovery of CD8+ T cell epitopes in Chlamydia trachomatis infection through use of caged class I MHC tetramers

(2008) G. M. Grotenbreg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA