UFMylation of MRE11 is essential for telomere length maintenance and hematopoietic stem cell survival

TRF2-mediated telomere protection is dispensable in pluripotent stem cells

(2020) Marta Markiewicz-Potoczny et al.   NATURE

TRF2-independent chromosome end protection during pluripotency

(2020) Phil Ruis et al.   NATURE

CDK5RAP3, a UFL1 substrate adaptor, is critical for liver development

(2019) Rui Yang et al.   DEVELOPMENT

Ribosomal protein RPL26 is the principal target of UFMylation

(2019) Christopher P. Walczak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Indispensable role of the Ubiquitin-fold modifier 1-specific E3 ligase in maintaining intestinal homeostasis and controlling gut inflammation

(2019) Yafei Cai et al.   Cell Discovery

UFL1 promotes histone H4 ufmylation and ATM activation

(2019) Bo Qin et al.   Nature Communications

Ufbp1 promotes plasma cell development and ER expansion by modulating distinct branches of UPR

(2019) Huabin Zhu et al.   Nature Communications

MRE11 UFMylation promotes ATM activation

(2019) Zhifeng Wang et al.   NUCLEIC ACIDS RESEARCH

Biallelic UFM1 and UFC1 mutations expand the essential role of ufmylation in brain development

(2018) Michael S Nahorski et al.   BRAIN

Ufm1-Specific Ligase Ufl1 Regulates Endoplasmic Reticulum Homeostasis and Protects Against Heart Failure

(2018) Jie Li et al.   Circulation-Heart Failure

Role of the Mre11 Complex in Preserving Genome Integrity

(2018) Julyun Oh et al.   Genes

NBS1 Phosphorylation Status Dictates Repair Choice of Dysfunctional Telomeres

(2017) Rekha Rai et al.   MOLECULAR CELL

A method for measuring the distribution of the shortest telomeres in cells and tissues

(2017) Tsung-Po Lai et al.   Nature Communications

Role of Telomeres and Telomerase in Aging and Cancer

(2016) J. W. Shay   Cancer Discovery

Hematopoietic Stem Cell Arrival Triggers Dynamic Remodeling of the Perivascular Niche

(2015) Owen J. Tamplin et al.   CELL

RCAD/Ufl1, a Ufm1 E3 ligase, is essential for hematopoietic stem cell function and murine hematopoiesis

(2015) M Zhang et al.   CELL DEATH AND DIFFERENTIATION

UFBP1, a Key Component of the Ufm1 Conjugation System, Is Essential for Ufmylation-Mediated Regulation of Erythroid Development

(2015) Yafei Cai et al.   PLoS Genetics

Modification of ASC1 by UFM1 Is Crucial for ERα Transactivation and Breast Cancer Development

(2014) Hee Min Yoo et al.   MOLECULAR CELL

Improved Genome Editing in Human Cell Lines Using the CRISPR Method

(2014) Ivan M. Munoz et al.   PLoS One

A non-canonical function of telomerase RNA in the regulation of developmental myelopoiesis in zebrafish

(2014) Francisca Alcaraz-Pérez et al.   Nature Communications

TERRA-Reinforced Association of LSD1 with MRE11 Promotes Processing of Uncapped Telomeres

(2014) Antonio Porro et al.   Cell Reports

The Ufm1 Cascade

(2014) Jens Daniel et al.   Cells

TeloTool: a new tool for telomere length measurement from terminal restriction fragment analysis with improved probe intensity correction

(2013) Janett Göhring et al.   NUCLEIC ACIDS RESEARCH

Zebrafish globin switching occurs in two developmental stages and is controlled by the LCR

(2012) Jared J. Ganis et al.   DEVELOPMENTAL BIOLOGY

The MRE11 complex: starting from the ends

(2011) Travis H. Stracker et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Ufm1-activating enzyme Uba5 is indispensable for erythroid differentiation in mice

(2011) Kanako Tatsumi et al.   Nature Communications

SNMIB/Apollo protects leading-strand telomeres against NHEJ-mediated repair

(2010) Yung C Lam et al.   EMBO JOURNAL

Cdc13 and Telomerase Bind through Different Mechanisms at the Lagging- and Leading-Strand Telomeres

(2010) Virginie Faure et al.   MOLECULAR CELL

Apollo Contributes to G Overhang Maintenance and Protects Leading-End Telomeres

(2010) Peng Wu et al.   MOLECULAR CELL

Function of Apollo (SNM1B) at telomere highlighted by a splice variant identified in a patient with Hoyeraal-Hreidarsson syndrome

(2010) F. Touzot et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Mre11 Complex and the Response to Dysfunctional Telomeres

(2009) C. L. Attwooll et al.   MOLECULAR AND CELLULAR BIOLOGY

Cell Cycle-Dependent Role of MRN at Dysfunctional Telomeres: ATM Signaling-Dependent Induction of Nonhomologous End Joining (NHEJ) in G1 and Resection-Mediated Inhibition of NHEJ in G2

(2009) N. Dimitrova et al.   MOLECULAR AND CELLULAR BIOLOGY

Multiple roles for MRE11 at uncapped telomeres

(2009) Yibin Deng et al.   NATURE

Origin and function of ubiquitin-like proteins

(2009) Mark Hochstrasser   NATURE