Adhesion G protein–coupled receptor Gpr126/Adgrg6 is essential for placental development

Structural basis for adhesion G protein-coupled receptor Gpr126 function

(2020) Katherine Leon et al.   Nature Communications

Regulation of body length and bone mass by Gpr126/Adgrg6

(2020) Peng Sun et al.   Science Advances

Genetic compensation triggered by mutant mRNA degradation

(2019) Mohamed A. El-Brolosy et al.   NATURE

Identification of compounds that rescue otic and myelination defects in the zebrafish adgrg6 (gpr126) mutant

(2019) Elvira Diamantopoulou et al.   eLife

Development of the human placenta

(2019) Margherita Y. Turco et al.   DEVELOPMENT

Regulators of G-Protein Signaling in Cardiovascular Function During Pregnancy

(2018) Katherine J. Perschbacher et al.   PHYSIOLOGICAL GENOMICS

Near to One's Heart: The Intimate Relationship Between the Placenta and Fetal Heart

(2018) Emily J. Camm et al.   Frontiers in Physiology

Placentation defects are highly prevalent in embryonic lethal mouse mutants

(2018) Vicente Perez-Garcia et al.   NATURE

The Role of Abnormal Placentation in Congenital Heart Disease; Cause, Correlate, or Consequence?

(2018) Jennifer A. Courtney et al.   Frontiers in Physiology

Regulation of Placental Development and Its Impact on Fetal Growth—New Insights From Mouse Models

(2018) Laura Woods et al.   Frontiers in Endocrinology

Transplacental Nutrient Transport Mechanisms of Intrauterine Growth Restriction in Rodent Models and Humans

(2017) Elke Winterhager et al.   Frontiers in Physiology

The force within: endocardial development, mechanotransduction and signalling during cardiac morphogenesis

(2016) Timm Haack et al.   DEVELOPMENT

Myocardial VHL-HIF Signaling Controls an Embryonic Metabolic Switch Essential for Cardiac Maturation

(2016) Ivan Menendez-Montes et al.   DEVELOPMENTAL CELL

Enhancing homology-directed genome editing by catalytically active and inactive CRISPR-Cas9 using asymmetric donor DNA

(2016) Christopher D Richardson et al.   NATURE BIOTECHNOLOGY

Cardiac electrical defects in progeroid mice and Hutchinson–Gilford progeria syndrome patients with nuclear lamina alterations

(2016) José Rivera-Torres et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RS-1 enhances CRISPR/Cas9- and TALEN-mediated knock-in efficiency

(2016) Jun Song et al.   Nature Communications

Mutations of GPR126 Are Responsible for Severe Arthrogryposis Multiplex Congenita

(2015) Gianina Ravenscroft et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Defining the gene repertoire and spatiotemporal expression profiles of adhesion G protein-coupled receptors in zebrafish

(2015) Breanne L Harty et al.   BMC GENOMICS

Sequential Notch activation regulates ventricular chamber development

(2015) Gaetano D’Amato et al.   NATURE CELL BIOLOGY

The Adhesion GPCR GPR126 Has Distinct, Domain-Dependent Functions in Schwann Cell Development Mediated by Interaction with Laminin-211

(2015) Sarah C. Petersen et al.   NEURON

Long-term outcome for patients with arthrogryposis multiplex congenita

(2015) Jean Dubousset et al.   Journal of Childrens Orthopaedics

Development of the hemochorial maternal vascular spaces in the placenta through endothelial and vasculogenic mimicry

(2014) Anshita Rai et al.   DEVELOPMENTAL BIOLOGY

Efficient Mutagenesis by Cas9 Protein-Mediated Oligonucleotide Insertion and Large-Scale Assessment of Single-Guide RNAs

(2014) James A. Gagnon et al.   PLoS One

Type IV collagen is an activating ligand for the adhesion G protein-coupled receptor GPR126

(2014) K. J. Paavola et al.   Science Signaling

A Tethered Agonist within the Ectodomain Activates the Adhesion G Protein-Coupled Receptors GPR126 and GPR133

(2014) Ines Liebscher et al.   Cell Reports

Analysis of Gpr126 function defines distinct mechanisms controlling the initiation and maturation of myelin

(2013) T. D. Glenn et al.   DEVELOPMENT

Semicircular canal morphogenesis in the zebrafish inner ear requires the function of gpr126 (lauscher), an adhesion class G protein-coupled receptor gene

(2013) F.-S. Geng et al.   DEVELOPMENT

Gpr126 Functions in Schwann Cells to Control Differentiation and Myelination via G-Protein Activation

(2013) A. Mogha et al.   JOURNAL OF NEUROSCIENCE

Genetic variants in GPR126 are associated with adolescent idiopathic scoliosis

(2013) Ikuyo Kou et al.   NATURE GENETICS

Organ-specific function of adhesion G protein-coupled receptor GPR126 is domain-dependent

(2013) C. Patra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Matrix metalloproteinase-9 deficiency phenocopies features of preeclampsia and intrauterine growth restriction

(2013) V. Plaks et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GO-Elite: a flexible solution for pathway and ontology over-representation

(2012) Alexander C. Zambon et al.   BIOINFORMATICS

Endocardial Cells Form the Coronary Arteries by Angiogenesis through Myocardial-Endocardial VEGF Signaling

(2012) Bingruo Wu et al.   CELL

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

(2011) Bo Li et al.   BMC BIOINFORMATICS

Gpr126 is essential for peripheral nerve development and myelination in mammals

(2011) K. R. Monk et al.   DEVELOPMENT

ADAM17 regulates TNFα production by placental trophoblasts

(2011) R. Ma et al.   PLACENTA

A dual role for ErbB2 signaling in cardiac trabeculation

(2010) J. Liu et al.   DEVELOPMENT

Cellular and Molecular Regulation of Spiral Artery Remodelling: Lessons from the Cardiovascular Field

(2010) G.St.J. Whitley et al.   PLACENTA

Review: Trophoblast-Vascular Cell Interactions in Early Pregnancy: How to Remodel a Vessel

(2010) L.K. Harris   PLACENTA

The Orphan Adhesion-GPCR GPR126 Is Required for Embryonic Development in the Mouse

(2010) Helen Waller-Evans et al.   PLoS One

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

The Role of Hypoxia in Development of the Mammalian Embryo

(2009) Sally L. Dunwoodie   DEVELOPMENTAL CELL

Expression of matrix metalloproteinases 2 and 9 in human trophoblasts of normal and preeclamptic placentas: Preliminary findings

(2009) Mahmoud Shokry et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Development and function of trophoblast giant cells in the rodent placenta

(2009) Dong Hu et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Isolation of Plasma Membrane Vesicles from Mouse Placenta at Term and Measurement of System A and System β Amino Acid Transporter Activity

(2009) L.C. Kusinski et al.   PLACENTA

Syncytin-A knockout mice demonstrate the critical role in placentation of a fusogenic, endogenous retrovirus-derived, envelope gene

(2009) A. Dupressoir et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The cAMP binding protein Epac regulates cardiac myofilament function

(2009) O. Cazorla et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A G Protein-Coupled Receptor Is Essential for Schwann Cells to Initiate Myelination

(2009) K. R. Monk et al.   SCIENCE

Early patterning of the chorion leads to the trilaminar trophoblast cell structure in the placental labyrinth

(2008) D. G. Simmons et al.   DEVELOPMENT

Foxn4 directly regulates tbx2b expression and atrioventricular canal formation

(2008) N. C. Chi et al.   GENES & DEVELOPMENT