Lentiviral and adeno-associated vectors efficiently transduce mouse T lymphocytes when targeted to murine CD8

Genetic in vivo engineering of human T lymphocytes in mouse models

(2021) Tatjana Weidner et al.   Nature Protocols

Adeno-Associated Virus Vector for Central Nervous System Gene Therapy

(2021) Danqing Zhu et al.   TRENDS IN MOLECULAR MEDICINE

IFNg is Critical for CAR T Cell Mediated Myeloid Activation and Induction of Endogenous Immunity

(2021) Darya Alizadeh et al.   Cancer Discovery

CAR T-cell product performance in haematological malignancies before and after marketing authorisation

(2020) Magdi Elsallab et al.   LANCET ONCOLOGY

CD8-Specific Designed Ankyrin Repeat Proteins Improve Selective Gene Delivery into Human and Primate T Lymphocytes

(2020) Annika M. Frank et al.   HUMAN GENE THERAPY

In Vivo Generation of CAR T Cells Selectively in Human CD4+ Lymphocytes

(2020) Shiwani Agarwal et al.   MOLECULAR THERAPY

In vivo engineering of lymphocytes after systemic exosome-associated AAV delivery

(2020) Cort B. Breuer et al.   Scientific Reports

Chimäre Antigenrezeptoren (CARs) in der Onkologie: eine Übersicht zu klinischer Anwendung und neuen Entwicklungen

(2020) Alexander Michels et al.   Bundesgesundheitsblatt-Gesundheitsforschung-Gesundheitsschutz

Current Clinical Applications of In Vivo Gene Therapy with AAVs

(2020) Jerry R. Mendell et al.   MOLECULAR THERAPY

In vitro-transcribed antigen receptor mRNA nanocarriers for transient expression in circulating T cells in vivo

(2020) N. N. Parayath et al.   Nature Communications

Genetic engineering of hematopoiesis: current stage of clinical translation and future perspectives

(2019) Luigi Naldini   EMBO Molecular Medicine

Highly efficient and selective CAR-gene transfer using CD4- and CD8-targeted lentiviral vectors

(2019) Arezoo Jamali et al.   Molecular Therapy-Methods & Clinical Development

GluA4-targeted AAV vectors deliver genes selectively to interneurons while relying on the AAV receptor for entry

(2019) Jessica Hartmann et al.   Molecular Therapy-Methods & Clinical Development

Nanobody-enhanced targeting of AAV gene therapy vectors

(2019) Anna Marei Eichhoff et al.   Molecular Therapy-Methods & Clinical Development

Gene therapy for severe combined immunodeficiencies and beyond

(2019) Alain Fischer et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Chimeric Antigen Receptor Therapy

(2018) Carl H. June et al.   NEW ENGLAND JOURNAL OF MEDICINE

A library-based screening strategy for the identification of DARPins as ligands for receptor-targeted AAV and lentiviral vectors

(2018) Jessica Hartmann et al.   Molecular Therapy-Methods & Clinical Development

In vivo generation of human CD19‐CAR T cells results in B‐cell depletion and signs of cytokine release syndrome

(2018) Anett Pfeiffer et al.   EMBO Molecular Medicine

Surface-Engineered Lentiviral Vectors for Selective Gene Transfer into Subtypes of Lymphocytes

(2018) Annika M. Frank et al.   Molecular Therapy-Methods & Clinical Development

An essential receptor for adeno-associated virus infection

(2016) S. Pillay et al.   NATURE

IL-7 Induces SAMHD1 Phosphorylation in CD4+ T Lymphocytes, Improving Early Steps of HIV-1 Life Cycle

(2016) Mayte Coiras et al.   Cell Reports

Designed Ankyrin Repeat Proteins (DARPins): Binding Proteins for Research, Diagnostics, and Therapy

(2015) Andreas Plückthun   Annual Review of Pharmacology and Toxicology

Surface-Engineered Viral Vectors for Selective and Cell Type-Specific Gene Delivery

(2015) Christian J. Buchholz et al.   TRENDS IN BIOTECHNOLOGY

Off-target-free gene delivery by affinity-purified receptor-targeted viral vectors

(2015) Robert C. Münch et al.   Nature Communications

Antiretroviral restriction factors in mice

(2014) Smita Nair et al.   VIRUS RESEARCH

Design, construction, and characterization of a second-generation DARPin library with reduced hydrophobicity

(2013) Markus A. Seeger et al.   PROTEIN SCIENCE

Mouse SAMHD1 Has Antiretroviral Activity and Suppresses a Spontaneous Cell-Intrinsic Antiviral Response

(2013) Rayk Behrendt et al.   Cell Reports

Extensive Methylation of Promoter Sequences Silences Lentiviral Transgene Expression During Stem Cell Differentiation In Vivo

(2012) Friederike Herbst et al.   MOLECULAR THERAPY

Displaying High-affinity Ligands on Adeno-associated Viral Vectors Enables Tumor Cell-specific and Safe Gene Transfer

(2012) Robert C Münch et al.   MOLECULAR THERAPY

Random Insertion of mCherry Into VP3 Domain of Adeno-associated Virus Yields Fluorescent Capsids With no Loss of Infectivity

(2012) Justin Judd et al.   Molecular Therapy-Nucleic Acids

Genetic Engineering of Murine CD8+ and CD4+ T Cells for Preclinical Adoptive Immunotherapy Studies

(2011) Sid P. Kerkar et al.   JOURNAL OF IMMUNOTHERAPY

Protein Transfer Into Human Cells by VSV-G-induced Nanovesicles

(2011) Philippe-Emmanuel Mangeot et al.   MOLECULAR THERAPY

Adoptive transfer of syngeneic T cells transduced with a chimeric antigen receptor that recognizes murine CD19 can eradicate lymphoma and normal B cells

(2010) J. N. Kochenderfer et al.   BLOOD

Specific gene transfer to neurons, endothelial cells and hematopoietic progenitors with lentiviral vectors

(2010) Brigitte Anliker et al.   NATURE METHODS

Pseudotyping lentiviral vectors with the wild-type measles virus glycoproteins improves titer and selectivity

(2009) S Funke et al.   GENE THERAPY

Relief of Preintegration Inhibition and Characterization of Additional Blocks for HIV Replication in Primary Mouse T Cells

(2008) Jing-xin Zhang et al.   PLoS One