IL-15 Participates in the Pathogenesis of Polycystic Ovary Syndrome by Affecting the Activity of Granulosa Cells

Association of metabolic and inflammatory markers with polycystic ovarian syndrome (PCOS): an update

(2021) Subeka Abraham Gnanadass et al.   ARCHIVES OF GYNECOLOGY AND OBSTETRICS

Inflammation and reproductive function in women with polycystic ovary syndrome†

(2021) Leandro M Velez et al.   BIOLOGY OF REPRODUCTION

A high-androgen microenvironment inhibits granulosa cell proliferation and alters cell identity

(2021) Renee M. McFee et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Age and Interleukin-15 Levels Are Independently Associated With Intima-Media Thickness in Obesity-Related NAFLD Patients

(2021) Giovanni Tarantino et al.   Frontiers in Medicine

Correlation between leptin and IFN-γ involved in granulosa cell apoptosis in PCOS

(2020) Juan Wang et al.   GYNECOLOGICAL ENDOCRINOLOGY

TGF-β and IL-15 Synergize through MAPK Pathways to Drive the Conversion of Human NK Cells to an Innate Lymphoid Cell 1–like Phenotype

(2020) Lindsey G. Hawke et al.   JOURNAL OF IMMUNOLOGY

Inhibition of autophagy in theca cells induces CYP17A1 and PAI-1 expression via ROS/p38 and JNK signalling during the development of polycystic ovary syndrome

(2020) Mutsumi Kobayashi et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Dapk1 improves inflammation, oxidative stress and autophagy in LPS-induced acute lung injury via p38MAPK/NF-κB signaling pathway

(2020) Tao Li et al.   MOLECULAR IMMUNOLOGY

Pathophysiological roles of chronic low‐grade inflammation mediators in polycystic ovary syndrome

(2020) Maryam Rostamtabar et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The role of serum inflammatory cytokines and berberine in the insulin signaling pathway among women with polycystic ovary syndrome

(2020) Hongying Kuang et al.   PLoS One

The AKT Activator SC79 Protects Hepatocytes from TNFα-mediated Apoptosis and Alleviates D-Gal/LPS-induced Liver Injury

(2019) Zhen-Tang Jing et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

New drugs under investigation for the treatment of alopecias

(2019) Jorge Ocampo-Garza et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Loss of growth hormone–mediated signal transducer and activator of transcription 5 (STAT5) signaling in mice results in insulin sensitivity with obesity

(2019) Yash Chhabra et al.   FASEB JOURNAL

Effect of the neuropeptide phoenixin and its receptor GPR173 during folliculogenesis

(2019) Xuan Phuoc Nguyen et al.   REPRODUCTION

Metabolically healthy obesity: facts and fantasies

(2019) Gordon I. Smith et al.   JOURNAL OF CLINICAL INVESTIGATION

Polycystic ovary syndrome: possible involvement of androgen-induced, chemerin-mediated ovarian recruitment of monocytes/macrophages†

(2018) Patricia D A Lima et al.   BIOLOGY OF REPRODUCTION

Interleukin 15 concentrations in follicular fluid and their effect on oocyte maturation in subfertile women undergoing intracytoplasmic sperm injection

(2018) S. Spanou et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Polycystic ovary syndrome: definition, aetiology, diagnosis and treatment

(2018) Héctor F. Escobar-Morreale   Nature Reviews Endocrinology

Activation of TGF‐β1/Smad3 signaling pathway inhibits the development of ovarian follicle in polycystic ovary syndrome by promoting apoptosis of granulosa cells

(2018) Haoran Shen et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Ring Finger Protein 6 Mediates Androgen-Induced Granulosa Cell Proliferation and Follicle Growth via Modulation of Androgen Receptor Signaling

(2017) Jung Jin Lim et al.   ENDOCRINOLOGY

Disruption of aromatase homeostasis as the cause of a multiplicity of ailments: A comprehensive review

(2017) Seema Patel   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Interleukin-15 in obesity and metabolic dysfunction: current understanding and future perspectives

(2017) Y. Duan et al.   Obesity Reviews

PRDM5 promotes the apoptosis of epithelial cells induced by IFN-γ during Crohn’s disease

(2017) Han Wu et al.   PATHOLOGY RESEARCH AND PRACTICE

Regulation of androgen receptor signaling by ubiquitination during folliculogenesis and its possible dysregulation in polycystic ovarian syndrome

(2017) Jung Jin Lim et al.   Scientific Reports

Altered FoxO3 expression and apoptosis in granulosa cells of women with polycystic ovary syndrome

(2016) Saideh Mikaeili et al.   ARCHIVES OF GYNECOLOGY AND OBSTETRICS

Criteria, prevalence, and phenotypes of polycystic ovary syndrome

(2016) Daria Lizneva et al.   FERTILITY AND STERILITY

Are CRH & NGF as psychoneuroimmune regulators in women with polycystic ovary syndrome?

(2016) F. Z. Zangeneh et al.   GYNECOLOGICAL ENDOCRINOLOGY

Interactions between androgens, FSH, anti-Müllerian hormone and estradiol during folliculogenesis in the human normal and polycystic ovary

(2016) Didier Dewailly et al.   HUMAN REPRODUCTION UPDATE

Enhanced Inflammatory Transcriptome in the Granulosa Cells of Women With Polycystic Ovarian Syndrome

(2016) Jaye Adams et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Insulin Resistance in PCOS Patients Enhances Oxidative Stress and Leukocyte Adhesion: Role of Myeloperoxidase

(2016) Victor M. Victor et al.   PLoS One

Polycystic ovary syndrome

(2016) Ricardo Azziz et al.   Nature Reviews Disease Primers

Association between Polycystic Ovary Syndrome and Gut Microbiota

(2016) Yanjie Guo et al.   PLoS One

Deficiency of Interleukin-15 Confers Resistance to Obesity by Diminishing Inflammation and Enhancing the Thermogenic Function of Adipose Tissues

(2016) Gregory Lacraz et al.   PLoS One

Biomarker Profiles in Women with PCOS and PCOS Offspring; A Pilot Study

(2016) Nadine M. P. Daan et al.   PLoS One

Interleukins 6 and 15 Levels Are Higher in Subcutaneous Adipose Tissue, but Obesity Is Associated with Their Increased Content in Visceral Fat Depots

(2015) Marta Jonas et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

IL-15 Superagonist–Mediated Immunotoxicity: Role of NK Cells and IFN-γ

(2015) Yin Guo et al.   JOURNAL OF IMMUNOLOGY

Functional genomics of PCOS: from GWAS to molecular mechanisms

(2015) Jan M. McAllister et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Obesity, inflammation, and the gut microbiota

(2015) Amanda J Cox et al.   Lancet Diabetes & Endocrinology

Interleukin-15 and Soluble Interleukin-15 Receptor α in Coronary Artery Disease Patients: Association with Epicardial Fat and Indices of Adipose Tissue Distribution

(2014) Elena Dozio et al.   PLoS One

Beneficial metabolic activities of inflammatory cytokine interleukin 15 in obesity and type 2 diabetes

(2014) Jianping Ye   Frontiers of Medicine

CYP17A1: A Biochemistry, Chemistry, and Clinical Review

(2013) David Porubek   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Effect of HSP10 on apoptosis induced by testosterone in cultured mouse ovarian granulosa cells

(2013) Kao-Kao Zhao et al.   European Journal of Obstetrics & Gynecology and Reproductive Biology

Phosphorylation of Human Cytochrome P450c17 by p38α Selectively Increases 17,20 Lyase Activity and Androgen Biosynthesis

(2013) Meng Kian Tee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Follicular Growth and Atresia in Mammalian Ovaries: Regulation by Survival and Death of Granulosa Cells

(2012) Fuko MATSUDA et al.   JOURNAL OF REPRODUCTION AND DEVELOPMENT

Mechanistic and structural insight into the functional dichotomy between IL-2 and IL-15

(2012) Aaron M Ring et al.   NATURE IMMUNOLOGY

IVF outcome in women with endometriosis in relation to tumour necrosis factor and anti-Müllerian hormone

(2010) H Falconer et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Plasma monocyte chemoattractant protein-1 (MCP-1) and macrophage inflammatory protein-1α are increased in patients with polycystic ovary syndrome (PCOS) and associated with adiposity, but unaffected by pioglitazone treatment

(2009) Dorte Glintborg et al.   CLINICAL ENDOCRINOLOGY

Blockade of IL-15 activity inhibits microglial activation through the NFκB, p38, and ERK1/2 pathways, reducing cytokine and chemokine release

(2009) Diego Gomez-Nicola et al.   GLIA