Assessing the Causal Role of Selenium in Amyotrophic Lateral Sclerosis: A Mendelian Randomization Study

A Matter of Concern – Trace Element Dyshomeostasis and Genomic Stability in Neurons

(2021) Viktoria K. Wandt et al.   Redox Biology

Constrained maximum likelihood-based Mendelian randomization robust to both correlated and uncorrelated pleiotropic effects

(2021) Haoran Xue et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A robust and efficient method for Mendelian randomization with hundreds of genetic variants

(2020) Stephen Burgess et al.   Nature Communications

Mendelian randomization accounting for correlated and uncorrelated pleiotropic effects using genome-wide summary statistics

(2020) Jean Morrison et al.   NATURE GENETICS

Environmental and Occupational Risk Factors of Amyotrophic Lateral Sclerosis: A Population-Based Case-Control Study

(2020) Tommaso Filippini et al.   International Journal of Environmental Research and Public Health

Blood metal levels and amyotrophic lateral sclerosis risk: a prospective cohort

(2020) Susan Peters et al.   ANNALS OF NEUROLOGY

Metal(loid)s role in the pathogenesis of amyotrophic lateral sclerosis: Environmental, epidemiological, and genetic data

(2020) Marina Tesauro et al.   ENVIRONMENTAL RESEARCH

Analysis of Trace Elements in Human Brain: Its Aim, Methods, and Concentration Levels

(2019) Cezary Grochowski et al.   Frontiers in Chemistry

Genetic Convergence Brings Clarity to the Enigmatic Red Line in ALS

(2019) Casey Cook et al.   NEURON

Mendelian randomization analysis using mixture models for robust and efficient estimation of causal effects

(2019) Guanghao Qi et al.   Nature Communications

Epidemiology of amyotrophic lateral sclerosis

(2019) Elisa Longinetti et al.   CURRENT OPINION IN NEUROLOGY

Exposure to a high selenium environment in Punjab, India: Biomarkers and health conditions

(2019) Rajinder Chawla et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Evaluating the potential role of pleiotropy in Mendelian randomization studies

(2018) Gibran Hemani et al.   HUMAN MOLECULAR GENETICS

Circulating Selenium and Prostate Cancer Risk: A Mendelian Randomization Analysis

(2018) James Yarmolinsky et al.   JNCI-Journal of the National Cancer Institute

Novel genes associated with amyotrophic lateral sclerosis: diagnostic and clinical implications

(2018) Ruth Chia et al.   LANCET NEUROLOGY

Genome-wide Analyses Identify KIF5A as a Novel ALS Gene

(2018) Aude Nicolas et al.   NEURON

Circulating Selenium and Prostate Cancer Risk: A Mendelian Randomization Analysis

(2018) James Yarmolinsky et al.   JNCI-Journal of the National Cancer Institute

Ionic Homeostasis Maintenance in ALS: Focus on New Therapeutic Targets

(2018) Rossana Sirabella et al.   Frontiers in Neuroscience

Sensitivity Analyses for Robust Causal Inference from Mendelian Randomization Analyses with Multiple Genetic Variants

(2017) Stephen Burgess et al.   EPIDEMIOLOGY

Interpreting findings from Mendelian randomization using the MR-Egger method

(2017) Stephen Burgess et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Mendelian Randomization

(2017) Connor A. Emdin et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Trace metal concentrations in hair and nails from Alzheimer’s disease patients: Relations with clinical severity

(2017) Emel Koseoglu et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Amyotrophic lateral sclerosis

(2017) Michael A van Es et al.   LANCET

Amyotrophic Lateral Sclerosis

(2017) Robert H. Brown et al.   NEW ENGLAND JOURNAL OF MEDICINE

A framework for the investigation of pleiotropy in two-sample summary data Mendelian randomization

(2017) Jack Bowden et al.   STATISTICS IN MEDICINE

Amyotrophic lateral sclerosis

(2017) Orla Hardiman et al.   Nature Reviews Disease Primers

Long-term mortality patterns in a residential cohort exposed to inorganic selenium in drinking water

(2016) Marco Vinceti et al.   ENVIRONMENTAL RESEARCH

Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator

(2016) Jack Bowden et al.   GENETIC EPIDEMIOLOGY

Two-sample Mendelian randomization: avoiding the downsides of a powerful, widely applicable but potentially fallible technique

(2016) Fernando Pires Hartwig et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Gene discovery in amyotrophic lateral sclerosis: implications for clinical management

(2016) Ammar Al-Chalabi et al.   Nature Reviews Neurology

Gender as a key factor in trace metal and metalloid content of human scalp hair. A multi-site study

(2016) Tamburo E. et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Amyotrophic lateral sclerosis: mechanisms and therapeutics in the epigenomic era

(2015) Ximena Paez-Colasante et al.   Nature Reviews Neurology

Genome-wide association study of selenium concentrations

(2014) Marilyn C. Cornelis et al.   HUMAN MOLECULAR GENETICS

Mendelian randomization: genetic anchors for causal inference in epidemiological studies

(2014) G. Davey Smith et al.   HUMAN MOLECULAR GENETICS

Analysis of amyotrophic lateral sclerosis as a multistep process: a population-based modelling study

(2014) Ammar Al-Chalabi et al.   LANCET NEUROLOGY

The phenotypic variability of amyotrophic lateral sclerosis

(2014) Bart Swinnen et al.   Nature Reviews Neurology

Genome-wide association study identifies loci affecting blood copper, selenium and zinc

(2013) David M. Evans et al.   HUMAN MOLECULAR GENETICS

Cerebrospinal fluid of newly diagnosed amyotrophic lateral sclerosis patients exhibits abnormal levels of selenium species including elevated selenite

(2013) Marco Vinceti et al.   NEUROTOXICOLOGY

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

(2012) Benjamin F Voight et al.   LANCET

Are environmental exposures to selenium, heavy metals, and pesticides risk factors for amyotrophic lateral sclerosis?

(2012) Marco Vinceti et al.   REVIEWS ON ENVIRONMENTAL HEALTH

Gender and age differences in mixed metal exposure and urinary excretion

(2011) Marika Berglund et al.   ENVIRONMENTAL RESEARCH

The relation between amyotrophic lateral sclerosis and inorganic selenium in drinking water: a population-based case-control study

(2010) Marco Vinceti et al.   Environmental Health

Major Lipids, Apolipoproteins, and Risk of Vascular Disease

(2009) The Emerging Risk Factors Collaboration*   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

A method for low volume and low Se concentration samples and application to paired cerebrospinal fluid and serum samples

(2009) Bernhard Michalke et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Association of Loss-of-Function Mutations in the ABCA1 Gene With High-Density Lipoprotein Cholesterol Levels and Risk of Ischemic Heart Disease

(2008) Ruth Frikke-Schmidt   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION