Irisin ameliorates doxorubicin-induced cardiac perivascular fibrosis through inhibiting endothelial-to-mesenchymal transition by regulating ROS accumulation and autophagy disorder in endothelial cells

Title
Irisin ameliorates doxorubicin-induced cardiac perivascular fibrosis through inhibiting endothelial-to-mesenchymal transition by regulating ROS accumulation and autophagy disorder in endothelial cells
Authors
Keywords
Doxorubicin-induced cardiotoxicity, Perivascular fibrosis, Endothelial-to-mesenchymal transition, Irisin, Reactive oxygen species, Autophagy
Journal
Redox Biology
Volume 46, Issue -, Pages 102120
Publisher
Elsevier BV
Online
2021-09-01
DOI
10.1016/j.redox.2021.102120

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