Altered gut metabolites and microbiota interactions are implicated in colorectal carcinogenesis and can be non-invasive diagnostic biomarkers

A Metabolite Array Technology for Precision Medicine

(2021) Guoxiang Xie et al.   ANALYTICAL CHEMISTRY

Amino acids in cancer

(2020) Elizabeth L. Lieu et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Microbiome in Colorectal Cancer: How to Get from Meta-omics to Mechanism?

(2020) Dominik Ternes et al.   TRENDS IN MICROBIOLOGY

Roles of aminoacyl-tRNA synthetase-interacting multi-functional proteins in physiology and cancer

(2020) Zheng Zhou et al.   Cell Death & Disease

The Janus-like role of proline metabolism in cancer

(2020) Lynsey Burke et al.   Cell Death Discovery

Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond

(2019) Michael Platten et al.   NATURE REVIEWS DRUG DISCOVERY

The Diverse Functions of Non-Essential Amino Acids in Cancer

(2019) Bo-Hyun Choi et al.   Cancers

Metagenomic and metabolomic analyses reveal distinct stage-specific phenotypes of the gut microbiota in colorectal cancer

(2019) Shinichi Yachida et al.   NATURE MEDICINE

Peptostreptococcus anaerobius promotes colorectal carcinogenesis and modulates tumour immunity

(2019) Xiaohang Long et al.   Nature Microbiology

New aspects of amino acid metabolism in cancer

(2019) Lisa Vettore et al.   BRITISH JOURNAL OF CANCER

Branched-chain amino acid metabolism in cancer

(2018) Elitsa A. Ananieva et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Synthesis of multi-omic data and community metabolic models reveals insights into the role of hydrogen sulfide in colon cancer

(2018) Vanessa L. Hale et al.   METHODS

Metabolomics Biomarkers for Detection of Colorectal Neoplasms: A Systematic Review

(2018) Vanessa Erben et al.   Cancers

Race-dependent association of sulfidogenic bacteria with colorectal cancer

(2017) Cemal Yazici et al.   GUT

A gut bacterial pathway metabolizes aromatic amino acids into nine circulating metabolites

(2017) Dylan Dodd et al.   NATURE

Gut flora profiling and fecal metabolite composition of colorectal cancer patients and healthy individuals

(2017) Xiaoxue Wang et al.   Experimental and Therapeutic Medicine

mixOmics: An R package for ‘omics feature selection and multiple data integration

(2017) Florian Rohart et al.   PLoS Computational Biology

Fecal Clostridium symbiosum for Noninvasive Detection of Early and Advanced Colorectal Cancer: Test and Validation Studies

(2017) Yuan-Hong Xie et al.   EBioMedicine

The Central Role of Amino Acids in Cancer Redox Homeostasis: Vulnerability Points of the Cancer Redox Code

(2017) Milica Vučetić et al.   Frontiers in Oncology

Complex heatmaps reveal patterns and correlations in multidimensional genomic data

(2016) Zuguang Gu et al.   BIOINFORMATICS

Quantitation of faecal Fusobacterium improves faecal immunochemical test in detecting advanced colorectal neoplasia

(2016) Sunny H Wong et al.   GUT

Fecal Microbiota, Fecal Metabolome, and Colorectal Cancer Interrelations

(2016) Rashmi Sinha et al.   PLoS One

A genome-wide systems analysis reveals strong link between colorectal cancer and trimethylamine N-oxide (TMAO), a gut microbial metabolite of dietary meat and fat

(2015) Rong Xu et al.   BMC GENOMICS

Revisit dietary fiber on colorectal cancer: butyrate and its role on prevention and treatment

(2015) J. C. Encarnação et al.   CANCER AND METASTASIS REVIEWS

Fusobacterium nucleatumin colorectal carcinoma tissue and patient prognosis

(2015) Kosuke Mima et al.   GUT

Diet, the Gut Microbiome, and Epigenetics

(2014) Meredith A. J. Hullar et al.   CANCER JOURNAL

Serine and glycine metabolism in cancer

(2014) Ivano Amelio et al.   TRENDS IN BIOCHEMICAL SCIENCES

Stool Microbiome and Metabolome Differences between Colorectal Cancer Patients and Healthy Adults

(2013) Tiffany L. Weir et al.   PLoS One

The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic Treg Cell Homeostasis

(2013) P. M. Smith et al.   SCIENCE

Microbiota impact on the epigenetic regulation of colorectal cancer

(2013) Tao Yang et al.   TRENDS IN MOLECULAR MEDICINE

A review of the potential mechanisms for the lowering of colorectal oncogenesis by butyrate

(2012) Kim Y. C. Fung et al.   BRITISH JOURNAL OF NUTRITION

Metagenomic microbial community profiling using unique clade-specific marker genes

(2012) Nicola Segata et al.   NATURE METHODS

Host-Gut Microbiota Metabolic Interactions

(2012) J. K. Nicholson et al.   SCIENCE

pROC: an open-source package for R and S+ to analyze and compare ROC curves

(2011) Xavier Robin et al.   BMC BIOINFORMATICS

Fermentation in the Human Large Intestine

(2011) George T. Macfarlane et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

DNA damage and toxicogenomic analyses of hydrogen sulfide in human intestinal epithelial FHs 74 Int cells

(2010) Matias S. Attene-Ramos et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Metabolomics and detection of colorectal cancer in humans: a systematic review

(2010) Haili Wang et al.   Future Oncology

The struggle within: Microbial influences on colorectal cancer

(2010) Janelle C. Arthur et al.   INFLAMMATORY BOWEL DISEASES

Adipose Tissue Fatty Acids in Breast Cancer Patients versus Healthy Control Women from Crete

(2009) G. Mamalakis et al.   ANNALS OF NUTRITION AND METABOLISM

Inhibition of S6K1 accounts partially for the anti-inflammatory effects of the arginase inhibitor L-norvaline

(2009) Xiu-Fen Ming et al.   BMC Cardiovascular Disorders