SIRPγ-CD47 Interaction Positively Regulates the Activation of Human T Cells in Situation of Chronic Stimulation

The SIRPα–CD47 immune checkpoint in NK cells

(2021) Tobias Deuse et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Immunotherapeutic Blockade of CD47 Inhibitory Signaling Enhances Innate and Adaptive Immune Responses to Viral Infection

(2020) Lamin B. Cham et al.   Cell Reports

CD47 Ligation Repositions the Inhibitory Receptor SIRPA to Suppress Integrin Activation and Phagocytosis

(2020) Meghan A. Morrissey et al.   IMMUNITY

Upregulation of CD47 Is a Host Checkpoint Response to Pathogen Recognition

(2020) Michal Caspi Tal et al.   mBio

Selective SIRPα blockade reverses tumor T cell exclusion and overcomes cancer immunotherapy resistance

(2020) Vanessa Gauttier et al.   JOURNAL OF CLINICAL INVESTIGATION

A functional subset of CD8+ T cells during chronic exhaustion is defined by SIRPα expression

(2019) Lara M. Myers et al.   Nature Communications

VISTA is an acidic pH-selective ligand for PSGL-1

(2019) Robert J. Johnston et al.   NATURE

An autoimmune disease risk SNP, rs2281808, in SIRPG is associated with reduced expression of SIRPγ and heightened effector state in human CD8 T-cells

(2018) Sushmita Sinha et al.   Scientific Reports

Anti-SIRPα antibody immunotherapy enhances neutrophil and macrophage antitumor activity

(2017) Nan Guo Ring et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MYC regulates the antitumor immune response through CD47 and PD-L1

(2016) S. C. Casey et al.   SCIENCE

Signals and Sequences That Control CD28 Localization to the Central Region of the Immunological Synapse

(2014) M. Sanchez-Lockhart et al.   JOURNAL OF IMMUNOLOGY

Targeting CD28, CTLA-4 and PD-L1 Costimulation Differentially Controls Immune Synapses and Function of Human Regulatory and Conventional T-Cells

(2013) Nahzli Dilek et al.   PLoS One

Crystal structure of signal regulatory protein gamma (SIRPγ) in complex with an antibody Fab fragment

(2013) Joanne E Nettleship et al.   BMC STRUCTURAL BIOLOGY

Human peripheral blood leucocyte non-obese diabetic-severe combined immunodeficiency interleukin-2 receptor gamma chain gene mouse model of xenogeneic graft-versus-host-like disease and the role of host major histocompatibility complex

(2009) M. A. King et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Endothelial CD47 interaction with SIRP  is required for human T-cell transendothelial migration under shear flow conditions in vitro

(2008) M. Stefanidakis et al.   BLOOD

Paired Receptor Specificity Explained by Structures of Signal Regulatory Proteins Alone and Complexed with CD47

(2008) Deborah Hatherley et al.   MOLECULAR CELL