VISTA is an acidic pH-selective ligand for PSGL-1

Comparison of immune infiltrates in melanoma and pancreatic cancer highlights VISTA as a potential target in pancreatic cancer

(2019) Jorge Blando et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD8 T Cell Exhaustion During Chronic Viral Infection and Cancer

(2019) Laura M. McLane et al.   Annual Review of Immunology

Structure and Functional Binding Epitope of V-domain Ig Suppressor of T Cell Activation

(2019) Nishant Mehta et al.   Cell Reports

T Cell Dysfunction in Cancer

(2018) Daniela S. Thommen et al.   CANCER CELL

Role of PD-1 during effector CD8 T cell differentiation

(2018) Eunseon Ahn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cancer immunotherapy using checkpoint blockade

(2018) Antoni Ribas et al.   SCIENCE

VSIG-3 as a ligand of VISTA inhibits human T cell function

(2018) Jinghua Wang et al.   IMMUNOLOGY

Blocking the VISTA pathway enhances disease progression in (NZB × NZW) F1 female mice

(2017) PA Sergent et al.   LUPUS

Negative immune checkpoint regulation by VISTA: a mechanism of acquired resistance to anti-PD-1 therapy in metastatic melanoma patients

(2017) Hojabr Kakavand et al.   MODERN PATHOLOGY

VISTA is an inhibitory immune checkpoint that is increased after ipilimumab therapy in patients with prostate cancer

(2017) Jianjun Gao et al.   NATURE MEDICINE

VISTA Deficiency Accelerates the Development of Fatal Murine Lupus Nephritis

(2017) Sabrina Ceeraz et al.   Arthritis & Rheumatology

PSGL-1 Is an Immune Checkpoint Regulator that Promotes T Cell Exhaustion

(2016) Roberto Tinoco et al.   IMMUNITY

Rapid Fine Conformational Epitope Mapping Using Comprehensive Mutagenesis and Deep Sequencing

(2015) Caitlin A. Kowalsky et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Immune-checkpoint proteins VISTA and PD-1 nonredundantly regulate murine T-cell responses

(2015) Jun Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Control of signaling-mediated clearance of apoptotic cells by the tumor suppressor p53

(2015) K. W. Yoon et al.   SCIENCE

VISTA Is an Immune Checkpoint Molecule for Human T Cells

(2014) J. L. Lines et al.   CANCER RESEARCH

VISTA Regulates the Development of Protective Antitumor Immunity

(2014) I. Le Mercier et al.   CANCER RESEARCH

Disruption of the immune-checkpoint VISTA gene imparts a proinflammatory phenotype with predisposition to the development of autoimmunity

(2014) L. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Development of an Autoimmune Syndrome Affecting the Skin and Internal Organs in P-Selectin Glycoprotein Ligand 1 Leukocyte Receptor-Deficient Mice

(2014) A. Pérez-Frías et al.   Arthritis & Rheumatology

Considering Protonation as a Posttranslational Modification Regulating Protein Structure and Function

(2013) André Schönichen et al.   Annual Review of Biophysics

Acidic extracellular microenvironment and cancer

(2013) Yasumasa Kato et al.   Cancer Cell International

Regulatory T Cells Suppress the Late Phase of the Immune Response in Lymph Nodes through P-Selectin Glycoprotein Ligand-1

(2013) S. Angiari et al.   JOURNAL OF IMMUNOLOGY

Ligand-based receptor identification on living cells and tissues using TRICEPS

(2013) Andreas P Frei et al.   Nature Protocols

PSGL-1 Regulates the Migration and Proliferation of CD8+ T Cells under Homeostatic Conditions

(2012) K. M. Veerman et al.   JOURNAL OF IMMUNOLOGY

Direct identification of ligand-receptor interactions on living cells and tissues

(2012) Andreas P Frei et al.   NATURE BIOTECHNOLOGY

VISTA, a novel mouse Ig superfamily ligand that negatively regulates T cell responses

(2011) Li Wang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: A Monoclonal Antibody Specific for the Programmed Death-1 Homolog Prevents Graft-versus-Host Disease in Mouse Models

(2011) D. B. Flies et al.   JOURNAL OF IMMUNOLOGY

P-selectin glycoprotein ligand-1 modulates immune inflammatory responses in the enteric lamina propria

(2011) Norman Nuñez-Andrade et al.   JOURNAL OF PATHOLOGY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PSGL-1 function in immunity and steady state homeostasis

(2009) Douglas A. Carlow et al.   IMMUNOLOGICAL REVIEWS

P-Selectin Glycoprotein Ligand-1 Negatively Regulates T-Cell Immune Responses

(2009) M. Matsumoto et al.   JOURNAL OF IMMUNOLOGY