Activation of RARα Receptor Attenuates Neuroinflammation After SAH via Promoting M1-to-M2 Phenotypic Polarization of Microglia and Regulating Mafb/Msr1/PI3K-Akt/NF-κB Pathway

The role of macrophage scavenger receptor 1 (Msr1) in prion pathogenesis

(2021) Bei Li et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

T0901317, an Agonist of Liver X Receptors, Attenuates Neuronal Apoptosis in Early Brain Injury after Subarachnoid Hemorrhage in Rats via Liver X Receptors/Interferon Regulatory Factor/P53 Upregulated Modulator of Apoptosis/Dynamin-1-Like Protein Pathway

(2021) Jiaxing Dai et al.   Oxidative Medicine and Cellular Longevity

SIRT1 Promotes M2 Microglia Polarization via Reducing ROS-Mediated NLRP3 Inflammasome Signaling After Subarachnoid Hemorrhage

(2021) Da-Yong Xia et al.   Frontiers in Immunology

Novel role of STAT3 in microglia-dependent neuroinflammation after experimental subarachnoid haemorrhage

(2021) Zhiyuan Vera Zheng et al.   JOURNAL OF INVESTIGATIVE MEDICINE

Inhibition of Ferroptosis Alleviates Early Brain Injury After Subarachnoid Hemorrhage In Vitro and In Vivo via Reduction of Lipid Peroxidation

(2020) Yuchen Li et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

MFG-E8 attenuates inflammation in subarachnoid hemorrhage by driving microglial M2 polarization

(2020) Yong-Yue Gao et al.   EXPERIMENTAL NEUROLOGY

Retinoic Acid Receptor Alpha Represses a Th9 Transcriptional and Epigenomic Program to Reduce Allergic Pathology

(2019) Daniella M. Schwartz et al.   IMMUNITY

Mesenchymal stem cells alleviate the early brain injury of subarachnoid hemorrhage partly by suppression of Notch1-dependent neuroinflammation: involvement of Botch

(2019) Wenchao Liu et al.   Journal of Neuroinflammation

Tamibarotene Improves Hippocampus Injury Induced by Focal Cerebral Ischemia-Reperfusion via Modulating PI3K/Akt Pathway in Rats

(2019) Xiaocui Tian et al.   Journal of Stroke & Cerebrovascular Diseases

Mitophagy Reduces Oxidative Stress Via Keap1 (Kelch-Like Epichlorohydrin-Associated Protein 1)/Nrf2 (Nuclear Factor-E2-Related Factor 2)/PHB2 (Prohibitin 2) Pathway After Subarachnoid Hemorrhage in Rats

(2019) Tongyu Zhang et al.   STROKE

Scavenger receptor A1 attenuates aortic dissection via promoting efferocytosis in macrophages

(2019) Zhi Zhang et al.   BIOCHEMICAL PHARMACOLOGY

Microglial Morphometric Parameters Correlate With the Expression Level of IL-1β, and Allow Identifying Different Activated Morphotypes

(2019) María del Mar Fernández-Arjona et al.   Frontiers in Cellular Neuroscience

The Dynamics of Microglial Polarization Reveal the Resident Neuroinflammatory Responses After Subarachnoid Hemorrhage

(2019) Zhiyuan Vera Zheng et al.   Translational Stroke Research

Quantifying Microglia Morphology from Photomicrographs of Immunohistochemistry Prepared Tissue Using ImageJ

(2018) Kimberly Young et al.   Jove-Journal of Visualized Experiments

Resident Microglia Activate before Peripheral Monocyte Infiltration and p75NTR Blockade Reduces Microglial Activation and Early Brain Injury after Subarachnoid Hemorrhage

(2018) Zhen Xu et al.   ACS Chemical Neuroscience

Docosahexaenoic Acid Alleviates Oxidative Stress-Based Apoptosis Via Improving Mitochondrial Dynamics in Early Brain Injury After Subarachnoid Hemorrhage

(2018) Tongyu Zhang et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Cooperative Therapeutic Action of Retinoic Acid Receptor and Retinoid X Receptor Agonists in a Mouse Model of Alzheimer's Disease

(2018) Kohichi Kawahara et al.   JOURNAL OF ALZHEIMERS DISEASE

TSG-6 attenuates inflammation-induced brain injury via modulation of microglial polarization in SAH rats through the SOCS3/STAT3 pathway

(2018) Ran Li et al.   Journal of Neuroinflammation

Asiatic acid attenuates methamphetamine-induced neuroinflammation and neurotoxicity through blocking of NF-kB/STAT3/ERK and mitochondria-mediated apoptosis pathway

(2017) Ji-Hyun Park et al.   Journal of Neuroinflammation

Isoliquiritigenin alleviates early brain injury after experimental intracerebral hemorrhage via suppressing ROS- and/or NF-κB-mediated NLRP3 inflammasome activation by promoting Nrf2 antioxidant pathway

(2017) Jun Zeng et al.   Journal of Neuroinflammation

MAFB prevents excess inflammation after ischemic stroke by accelerating clearance of damage signals through MSR1

(2017) Takashi Shichita et al.   NATURE MEDICINE

Mdivi-1 Alleviates Early Brain Injury After Experimental Subarachnoid Hemorrhage in Rats, Possibly via Inhibition of Drp1-Activated Mitochondrial Fission and Oxidative Stress

(2017) Pei Wu et al.   NEUROCHEMICAL RESEARCH

Neuroinflammation pathways: a general review

(2016) Tara Shabab et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Functions and mechanisms of microglia/macrophages in neuroinflammation and neurogenesis after stroke

(2016) Xiao-Yi Xiong et al.   PROGRESS IN NEUROBIOLOGY

Microglia inflict delayed brain injury after subarachnoid hemorrhage

(2015) Ulf C. Schneider et al.   ACTA NEUROPATHOLOGICA

Resident microglia, rather than blood-derived macrophages, contribute to the earlier and more pronounced inflammatory reaction in the immature compared with the adult hippocampus after hypoxia-ischemia

(2015) Takashi Umekawa et al.   GLIA

Scavenger Receptor-A (CD204): A Two-Edged Sword in Health and Disease

(2014) Jim L. Kelley et al.   CRITICAL REVIEWS IN IMMUNOLOGY

Novel PEG-grafted nanostructured lipid carrier for systematic delivery of a poorly soluble anti-leukemia agent Tamibarotene: characterization and evaluation

(2014) Xin Liu et al.   DRUG DELIVERY

Suppression of CXCL2 upregulation underlies the therapeutic effect of the retinoid Am80 on intracerebral hemorrhage in mice

(2014) Hideaki Matsushita et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Retinoids as potential targets for Alzheimer's disease

(2014) Rupinder K. Sodhi et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Bipolar/rod-shaped microglia are proliferating microglia with distinct M1/M2 phenotypes

(2014) Wing Yip Tam et al.   Scientific Reports

What is Early Brain Injury?

(2014) Hidenori Suzuki   Translational Stroke Research

Traumatic brain injury induces macrophage subsets in the brain

(2013) Christine L. Hsieh et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Amyloid β inhibits retinoic acid synthesis exacerbating Alzheimer disease pathology which can be attenuated by an retinoic acid receptor α agonist

(2013) Maria B. Goncalves et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Tamibarotene: A Candidate Retinoid Drug for Alzheimer’s Disease

(2012) Hiroshi Fukasawa et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Galectin-1 Deactivates Classically Activated Microglia and Protects from Inflammation-Induced Neurodegeneration

(2012) Sarah C. Starossom et al.   IMMUNITY

A Retinoic Acid Receptor Agonist Am80 Rescues Neurons, Attenuates Inflammatory Reactions, and Improves Behavioral Recovery after Intracerebral Hemorrhage in Mice

(2010) Hideaki Matsushita et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Retinoic acid receptor stimulation protects midbrain dopaminergic neurons from inflammatory degeneration via BDNF-mediated signaling

(2009) Hiroshi Katsuki et al.   JOURNAL OF NEUROCHEMISTRY

Identification of Two Distinct Macrophage Subsets with Divergent Effects Causing either Neurotoxicity or Regeneration in the Injured Mouse Spinal Cord

(2009) K. A. Kigerl et al.   JOURNAL OF NEUROSCIENCE

A new grading system evaluating bleeding scale in filament perforation subarachnoid hemorrhage rat model

(2007) Takashi Sugawara et al.   JOURNAL OF NEUROSCIENCE METHODS