Exosomes loaded with programmed death ligand-1 promote tumor growth by immunosuppression in osteosarcoma

Benchtop Isolation and Characterisation of Small Extracellular Vesicles from Human Mesenchymal Stem Cells

(2021) Kian Leong Tan et al.   MOLECULAR BIOTECHNOLOGY

Potential role of the PD-L1 expression and tumor-infiltrating lymphocytes on neuroblastoma

(2020) Shogo Zuo et al.   PEDIATRIC SURGERY INTERNATIONAL

Exosomal PD-L1 and N-cadherin predict pulmonary metastasis progression for osteosarcoma patients

(2020) Jun Wang et al.   JOURNAL OF NANOBIOTECHNOLOGY

Exosomal PD-L1 Retains Immunosuppressive Activity and is Associated with Gastric Cancer Prognosis

(2019) Yibo Fan et al.   ANNALS OF SURGICAL ONCOLOGY

Prognostic significance of PD-L1 expression and tumor-infiltrating lymphocytes in axial osteosarcoma

(2019) Ping Liu et al.   World Neurosurgery

Exosomes

(2019) D. Michiel Pegtel et al.   Annual Review of Biochemistry

Endogenous T cells prevent tumor immune escape following adoptive T cell therapy

(2019) Scott R. Walsh et al.   JOURNAL OF CLINICAL INVESTIGATION

The role of exosomal PD-L1 in tumor progression and immunotherapy

(2019) Feiting Xie et al.   Molecular Cancer

Blocking the PD-1/PD-L1 axis enhanced cisplatin chemotherapy in osteosarcoma in vitro and in vivo

(2019) Xiaoqiang Liu et al.   Environmental Health and Preventive Medicine

Exosomal PD-L1 harbors active defense function to suppress T cell killing of breast cancer cells and promote tumor growth

(2018) Yi Yang et al.   CELL RESEARCH

Prognostic Value of Programmed Cell Death 1 Ligand-1 (PD-L1) or PD-1 Expression in Patients with Osteosarcoma: A Meta-Analysis

(2018) Xin Huang et al.   Journal of Cancer

Oncogenic activation of the STAT3 pathway drives PD-L1 expression in natural killer/T-cell lymphoma

(2018) Tammy Linlin Song et al.   BLOOD

EBV-associated gastric cancer evades T-cell immunity by PD-1/PD-L1 interactions

(2018) Sho Sasaki et al.   Gastric Cancer

PD-1/PD-L1 immune checkpoint: Potential target for cancer therapy

(2018) Fatemeh K. Dermani et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Characterization of PD-L1 expression and immune cell infiltration in nasopharyngeal cancer

(2017) Oscar Siu Hong Chan et al.   ORAL ONCOLOGY

Herpesviruses hijack host exosomes for viral pathogenesis

(2017) Sara Sadeghipour et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

HLA class I loss and PD-L1 expression in lung cancer: impact on T-cell infiltration and immune escape

(2017) Francisco Perea et al.   Oncotarget

Targeting programmed cell death ligand 1 by CRISPR/Cas9 in osteosarcoma cells

(2017) Yunfei Liao et al.   Oncotarget

Targeting PD-1 and Tim-3 Pathways to Reverse CD8 T-Cell Exhaustion and Enhance Ex Vivo T-Cell Responses to Autologous Dendritic/Tumor Vaccines

(2016) Jingwei Liu et al.   JOURNAL OF IMMUNOTHERAPY

Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity

(2016) Chia-Wei Li et al.   Nature Communications

Immune infiltration and PD-L1 expression in the tumor microenvironment are prognostic in osteosarcoma

(2016) Pratistha Koirala et al.   Scientific Reports

Immune Checkpoint Blockade in Cancer Therapy

(2015) Michael A. Postow et al.   JOURNAL OF CLINICAL ONCOLOGY

Programmed death 1 expression in the peritumoral microenvironment is associated with a poorer prognosis in classical Hodgkin lymphoma

(2015) Young Wha Koh et al.   TUMOR BIOLOGY

NKT Cells in Tumor Immunity: Opposing Subsets Define a New Immunoregulatory Axis

(2014) J. A. Berzofsky et al.   JOURNAL OF IMMUNOLOGY

Effect of Nasopharyngeal Carcinoma-Derived Exosomes on Human Regulatory T Cells

(2014) Dhafer Mrizak et al.   JNCI-Journal of the National Cancer Institute

Programmed cell death 1 forms negative costimulatory microclusters that directly inhibit T cell receptor signaling by recruiting phosphatase SHP2

(2012) Tadashi Yokosuka et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tumor Immunotherapy Directed at PD-1

(2012) Antoni Ribas   NEW ENGLAND JOURNAL OF MEDICINE

Cancer Immunoediting: Integrating Immunity's Roles in Cancer Suppression and Promotion

(2011) R. D. Schreiber et al.   SCIENCE