Engineered Small Extracellular Vesicles as a FGL1/PD‐L1 Dual‐Targeting Delivery System for Alleviating Immune Rejection

Mechanisms underlying low-clinical responses to PD-1/PD-L1 blocking antibodies in immunotherapy of cancer: a key role of exosomal PD-L1

(2021) Zi Yin et al.   Journal for ImmunoTherapy of Cancer

NF45/NF90‐mediated rDNA transcription provides a novel target for immunosuppressant development

(2021) Hsiang‐i Tsai et al.   EMBO Molecular Medicine

Immune Checkpoints, a Novel Class of Therapeutic Targets for Autoimmune Diseases

(2021) Yujia Zhai et al.   Frontiers in Immunology

IL-2 “Backpacking” Invigorates Treg Cells to Prevent Allograft Rejection

(2021) Hinrich Abken   TRANSPLANTATION

VISTA is a checkpoint regulator for naïve T cell quiescence and peripheral tolerance

(2020) Mohamed A. ElTanbouly et al.   SCIENCE

Exosomal PD-L1 functions as an immunosuppressant to promote wound healing

(2020) Dandan Su et al.   Journal of Extracellular Vesicles

Progress and Challenges in Precise Treatment of Tumors With PD-1/PD-L1 Blockade

(2020) Youhai Jiang et al.   Frontiers in Immunology

Engineering Programmed Death Ligand-1/Cytotoxic T-Lymphocyte-Associated Antigen-4 Dual-Targeting Nanovesicles for Immunosuppressive Therapy in Transplantation

(2020) Zhanxue Xu et al.   ACS Nano

Gastrointestinal complications after kidney transplantation

(2020) Rossella Gioco et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Extracellular micro/nanovesicles rescue kidney from ischemia-reperfusion injury

(2019) Saeed Farzamfar et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Membrane-encapsulated camouflaged nanomedicines in drug delivery

(2019) Suparna Ghosh et al.   Nanomedicine

Latest advances in extracellular vesicles: from bench to bedside

(2019) Tomofumi Yamamoto et al.   SCIENCE AND TECHNOLOGY OF ADVANCED MATERIALS

Tacrolimus: 20 years of use in adult kidney transplantation. What we should know about its nephrotoxicity

(2019) Yassamine Bentata   ARTIFICIAL ORGANS

Assessment of the expression of the immune checkpoint molecules PD‐1, CTLA4, TIM‐3 and LAG‐3 across different cancers in relation to treatment response, tumor‐infiltrating immune cells and survival

(2019) Lei Tu et al.   INTERNATIONAL JOURNAL OF CANCER

PD-1 Blockade Cellular Vesicles for Cancer Immunotherapy

(2018) Xudong Zhang et al.   ADVANCED MATERIALS

Exosomes and Ectosomes in Intercellular Communication

(2018) Jacopo Meldolesi   CURRENT BIOLOGY

Cell-derived Exosomes as Promising Carriers for Drug Delivery and Targeted Therapy

(2018) Xinyi Wang et al.   CURRENT CANCER DRUG TARGETS

OUP accepted manuscript

(2018)   NEPHROLOGY DIALYSIS TRANSPLANTATION

Bioprinting Perfusion-Enabled Liver Equivalents for Advanced Organ-on-a-Chip Applications

(2018) Tobias Grix et al.   Genes

Engineering PD-1-Presenting Platelets for Cancer Immunotherapy

(2018) Xudong Zhang et al.   NANO LETTERS

Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response

(2018) Gang Chen et al.   NATURE

Fibrinogen-like Protein 1 Is a Major Immune Inhibitory Ligand of LAG-3

(2018) Jun Wang et al.   CELL

Development of transplant immunosuppressive agents – considerations in the use of animal models

(2018) Russell Costello et al.   Expert Opinion on Drug Discovery

A potent immunomodulatory role of exosomes derived from mesenchymal stromal cells in preventing cGVHD

(2018) Peilong Lai et al.   Journal of Hematology & Oncology

Revisiting the Concept of Targeting NFAT to Control T Cell Immunity and Autoimmune Diseases

(2018) Jae-Ung Lee et al.   Frontiers in Immunology

IL-21 restricts T follicular regulatory T cell proliferation through Bcl-6 mediated inhibition of responsiveness to IL-2

(2017) Christoph Jandl et al.   Nature Communications

PD-1 and PD-L1 Checkpoint Signaling Inhibition for Cancer Immunotherapy: Mechanism, Combinations, and Clinical Outcome

(2017) Hashem O. Alsaab et al.   Frontiers in Pharmacology

Regulation of chronic inflammatory and immune processes by extracellular vesicles

(2016) Paul D. Robbins et al.   JOURNAL OF CLINICAL INVESTIGATION

Extracellular Vesicles Released from Human Umbilical Cord-Derived Mesenchymal Stromal Cells Prevent Life-Threatening Acute Graft-Versus-Host Disease in a Mouse Model of Allogeneic Hematopoietic Stem Cell Transplantation

(2016) Li Wang et al.   STEM CELLS AND DEVELOPMENT

The biology of extracellular vesicles with focus on platelet microparticles and their role in cancer development and progression

(2016) M. Żmigrodzka et al.   TUMOR BIOLOGY

Emerging targets in cancer immunotherapy: beyond CTLA-4 and PD-1

(2015) Amer Assal et al.   Immunotherapy

LPS-preconditioned mesenchymal stromal cells modify macrophage polarization for resolution of chronic inflammation via exosome-shuttled let-7b

(2015) Dongdong Ti et al.   Journal of Translational Medicine

LAG3 and PD1 co-inhibitory molecules collaborate to limit CD8+ T cell signaling and dampen antitumor immunity in a murine ovarian cancer model

(2015) Ruea-Yea Huang et al.   Oncotarget

Cell or Cell Membrane-Based Drug Delivery Systems

(2015) Songwei Tan et al.   Theranostics

Prevention of acute liver allograft rejection by IL-10-engineered mesenchymal stem cells

(2014) J. Niu et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Distinct, Specific IL-17- and IL-22-Producing CD4+ T Cell Subsets Contribute to the Human Anti-Mycobacterial Immune Response

(2014) T. J. Scriba et al.   JOURNAL OF IMMUNOLOGY

MSC-derived exosomes: a novel tool to treat therapy-refractory graft-versus-host disease

(2014) L Kordelas et al.   LEUKEMIA

Mesenchymal Stem Cells Deliver Exogenous miRNAs to Neural Cells and Induce Their Differentiation and Glutamate Transporter Expression

(2014) Hae Kyung Lee et al.   STEM CELLS AND DEVELOPMENT

Immune checkpoint blockade immunotherapy to activate anti-tumour T-cell immunity

(2013) Alan G. Ramsay   BRITISH JOURNAL OF HAEMATOLOGY

CTLA-4 and PD-1/PD-L1 Blockade: New Immunotherapeutic Modalities with Durable Clinical Benefit in Melanoma Patients

(2013) P. A. Ott et al.   CLINICAL CANCER RESEARCH

IL-18 Induces Airway Hyperresponsiveness and Pulmonary Inflammation via CD4+ T Cell and IL-13

(2013) Masanori Sawada et al.   PLoS One

Imaging transplant rejection: a new view

(2011) Michael D Cahalan   NATURE MEDICINE

Rapamycin and tacrolimus differentially modulate acute graft-versus-host disease in rats after liver transplantation

(2009) Guodong Xu et al.   LIVER TRANSPLANTATION

Mesenchymal Stromal Cells — Current Understanding and Clinical Status

(2009) H. K. Salem et al.   STEM CELLS