NF45/NF90‐mediated rDNA transcription provides a novel target for immunosuppressant development

NF90 regulation of immune factor expression in response to malaria antigens

(2019) M. Laura Idda et al.   CELL CYCLE

Inducible expression of immediate early genes is regulated through dynamic chromatin association by NF45/ILF2 and NF90/NF110/ILF3

(2019) Ting-Hsuan Wu et al.   PLoS One

First-in-Human RNA Polymerase I Transcription Inhibitor CX-5461 in Patients with Advanced Hematological Cancers: Results of a Phase I Dose Escalation Study

(2019) Amit Khot et al.   Cancer Discovery

The Targeting of RNA Polymerase I Transcription Using CX-5461 in Combination with Radiation Enhances Tumour Cell Killing Effects in Human Solid Cancers

(2019) Mohammed Ismael et al.   Cancers

NFAT-Specific Inhibition by dNP2-VIVIT Ameliorates Autoimmune Encephalomyelitis by Regulation of Th1 and Th17

(2019) Hong-Gyun Lee et al.   Molecular Therapy-Methods & Clinical Development

Campath, calcineurin inhibitor reduction, and chronic allograft nephropathy (the 3C Study) - results of a randomized controlled clinical trial

(2018)   AMERICAN JOURNAL OF TRANSPLANTATION

44OCCTG IND.231: A phase 1 trial evaluating CX-5461 in patients with advanced solid tumors

(2018) J Hilton et al.   ANNALS OF ONCOLOGY

Nucleolar Function in Lifespan Regulation

(2018) Varnesh Tiku et al.   TRENDS IN CELL BIOLOGY

Development of transplant immunosuppressive agents – considerations in the use of animal models

(2018) Russell Costello et al.   Expert Opinion on Drug Discovery

Revisiting the Concept of Targeting NFAT to Control T Cell Immunity and Autoimmune Diseases

(2018) Jae-Ung Lee et al.   Frontiers in Immunology

Treg therapy in transplantation: a general overview

(2017) Marco Romano et al.   TRANSPLANT INTERNATIONAL

The Banff 2015 Kidney Meeting Report: Current Challenges in Rejection Classification and Prospects for Adopting Molecular Pathology

(2016) A. Loupy et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Regulatory T cells in kidney disease and transplantation

(2016) Min Hu et al.   KIDNEY INTERNATIONAL

CD8+ T cells in human autoimmune arthritis: the unusual suspects

(2016) Alessandra Petrelli et al.   Nature Reviews Rheumatology

Bone Marrow GvHD after Allogeneic Hematopoietic Stem Cell Transplantation

(2016) Martin Szyska et al.   Frontiers in Immunology

The NF45/NF90 Heterodimer Contributes to the Biogenesis of 60S Ribosomal Subunits and Influences Nucleolar Morphology

(2015) Franziska Wandrey et al.   MOLECULAR AND CELLULAR BIOLOGY

NF90 Exerts Antiviral Activity through Regulation of PKR Phosphorylation and Stress Granules in Infected Cells

(2014) X. Wen et al.   JOURNAL OF IMMUNOLOGY

Potentiating maternal immune tolerance in pregnancy: A new challenging role for regulatory T cells

(2014) J. Alijotas-Reig et al.   PLACENTA

Ilf3 and NF90 functions in RNA biology

(2014) Sandrine Castella et al.   Wiley Interdisciplinary Reviews-RNA

NF90 in Posttranscriptional Gene Regulation and MicroRNA Biogenesis

(2013) Kiyoshi Masuda et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

NF45 dimerizes with NF90, Zfr and SPNR via a conserved domain that has a nucleotidyltransferase fold

(2012) Urszula M. Wolkowicz et al.   NUCLEIC ACIDS RESEARCH

Effector CD4+ T cells, the cytokines they generate, and GVHD: something old and something new

(2011) J. M. Coghill et al.   BLOOD

Identification of DHX33 as a Mediator of rRNA Synthesis and Cell Growth

(2011) Y. Zhang et al.   MOLECULAR AND CELLULAR BIOLOGY

The NF90/NF45 Complex Participates in DNA Break Repair via Nonhomologous End Joining

(2011) R. A. Shamanna et al.   MOLECULAR AND CELLULAR BIOLOGY

Ribosome Assembly Factors Prevent Premature Translation Initiation by 40S Assembly Intermediates

(2011) B. S. Strunk et al.   SCIENCE

Targeting RNA Polymerase I with an Oral Small Molecule CX-5461 Inhibits Ribosomal RNA Synthesis and Solid Tumor Growth

(2010) Denis Drygin et al.   CANCER RESEARCH

NF45 and NF90 Regulate HS4-dependent Interleukin-13 Transcription in T Cells

(2010) Patricia Kiesler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nuclear Factor 45 (NF45) Is a Regulatory Subunit of Complexes with NF90/110 Involved in Mitotic Control

(2008) D. Guan et al.   MOLECULAR AND CELLULAR BIOLOGY