Editorial Material
Endocrinology & Metabolism
Sophie Leboulleux, Isabelle Borget, Martin Schlumberger
Summary: RAI treatment is used in thyroid cancer patients for disease treatment and removal of normal thyroid remnants. Routine post-operative administration of RAI is no longer recommended in low risk thyroid cancer patients.
NATURE REVIEWS ENDOCRINOLOGY
(2022)
Article
Multidisciplinary Sciences
Yusuke Iizuka, Tomohiro Katagiri, Kengo Ogura, Minoru Inoue, Ryota Nakashima, Kiyonao Nakamura, Takashi Mizowaki
Summary: This study evaluated the recurrence-free survival rates and factors related to recurrence in patients who underwent adjuvant therapy with radioactive iodine following thyroidectomy for differentiated thyroid cancer. A total of 284 patients were assessed, and the median observation period was 30.2 months. The 3-year recurrence-free survival rate was 85.8%, and histology and adjuvant therapy result were significant factors affecting the rate.
SCIENTIFIC REPORTS
(2023)
Article
Multidisciplinary Sciences
Jianhua Li, Wenping Xue, Pengfei Xu, Zhen Deng, Caiwen Duan, Danhua Zhang, Shouhua Zheng, Kefei Cui, Xinguang Qiu
Summary: The clinical outcomes of percutaneous radiofrequency ablation (RFA) for symptomatic benign thyroid nodules (BTNs) were evaluated in a retrospective observational study. The results showed that RFA was effective in treating symptomatic benign solid or cystic-solid nodules, with significantly better outcomes in cystic-solid nodules compared to solid nodules at the 3rd and 6th month.
SCIENTIFIC REPORTS
(2021)
Article
Oncology
Alfredo Campenni, Rosaria Maddalena Ruggeri, Maria Luisa Garo, Massimiliano Siracusa, Giovanna Restuccia, Andrea Rappazzo, Helena Rosarno, Antonio Nicocia, Davide Cardile, Petra Petranovic Ovcaricek, Sergio Baldari, Luca Giovanella
Summary: The aim of this study was to compare the efficacy of low (1.1 GBq) versus moderate (2.2 GBq) I-131 activities in low-risk differentiated thyroid carcinoma (DTC) patients requiring postoperative thyroid remnant ablation. The results showed that moderate I-131 activities led to a significantly higher proportion of patients with an excellent response compared to low I-131 activities (p = 0.029). Conversely, low I-131 activities were associated with a higher proportion of patients with a biochemically indeterminate or incomplete response (p = 0.001). Therefore, the use of moderate activities is encouraged to achieve better treatment outcomes.
Article
Medicine, General & Internal
Aleksandra Kukulska, Jolanta Krajewska, Marzena Gawkowska, Ewa Paliczka-Cieslik, Daria Handkiewicz-Junak, Aleksandra Kropinska, Zbigniew Puch, Tomasz Olczyk, Jozef Roskosz, Barbara Jarzab
Summary: This study evaluated the long-term outcomes of differentiated thyroid cancer (DTC) patients treated with different radioiodine (RAI) activities. The results showed that 30 mCi of RAI activity had comparable efficacy to 60 mCi and 100 mCi in low-risk DTC, while 60 mCi of RAI activity seemed to be effective in intermediate-risk DTC.
ARCHIVES OF MEDICAL SCIENCE
(2022)
Article
Multidisciplinary Sciences
Juan Xiao, Canhua Yun, Jingjia Cao, Shouluan Ding, Chunchun Shao, Lina Wang, Fengyan Huang, Hongying Jia
Summary: This study found that a pre-ablative TSH level of 30-70 mIU/L was appropriate for patients with differentiated thyroid carcinoma (DTC) to achieve a better response to initial radioiodine remnant ablation (RRA). Factors such as gender and lymph node dissection were also found to be associated with the response to RRA.
SCIENTIFIC REPORTS
(2021)
Article
Medicine, General & Internal
Simone De Leo, Matteo Trevisan, Carla Colombo, Giacomo Gazzano, Sonia Palazzo, Leonardo Vicentini, Luca Persani, Laura Fugazzola
Summary: This study demonstrated that patients with intrathyroidal DTC sized 1.1-4 cm do not benefit from RAI therapy. The outcome of these patients remains favorable, and a few persistent cases can be treated with RAI during follow-up.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Medicine, Research & Experimental
Haris Muhammad, Aniqa Tehreem, Jonathon O. Russell, Ralph P. Tufano
Summary: AFTNs have traditionally been treated with surgery or RAI, which can have complications. RFA is advocated as a minimally invasive alternative, showing promise especially for higher risk surgical candidates or RAI contraindications. Further studies with longer follow-up are needed to establish standardized protocols and generalize RFA use for AFTNs.
Article
Endocrinology & Metabolism
Vitor Bock Silveira, Wallace Klein Schwengber, Guilherme Moreira Hetzel, Andre B. Zanella, Rafael Selbach Scheffel, Ana Luiza Maia, Jose Miguel Dora
Summary: Restrictions during the COVID-19 pandemic significantly reduced diagnostic and treatment procedures for thyroid cancer in Brazil. FNABs, oncologic thyroidectomies, and RAI therapies all experienced a decrease in both 2020 and 2021, with the most pronounced reductions observed in 2020.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Multidisciplinary Sciences
Konrad Klimek, Nicolai Mader, Christian Happel, Amir Sabet, Frank Grunwald, Daniel Groener
Summary: The study aimed to investigate heat sink effects in radiofrequency ablation (RFA) under thyroid-specific conditions and found that significant heat sink effects were observed under thyroid-specific conditions, which may limit the efficacy of ablation even at low flow rates.
SCIENTIFIC REPORTS
(2023)
Article
Multidisciplinary Sciences
Piotr Szumowski, Saeid Abdelrazek, Dorota Iwanicka, Malgorzata Mojsak, Monika Sykala, Lukasz Zukowski, Katarzyna Siewko, Agnieszka Adamska, Katarzyna Maliszewska, Anna Poplawska-Kita, Malgorzata Szelachowska, Adam Kretowski, Janusz Mysliwiec
Summary: Dosimetry based on Marinelli's formula is essential for determining the radioiodine activity in adjuvant therapy for thyroid cancer. The retrospective analysis showed that adjusting therapeutic activities of I-131 based on dosimetry measurements can lead to successful outcomes for patients.
SCIENTIFIC REPORTS
(2021)
Article
Endocrinology & Metabolism
C. Saie, J. Wassermann, E. Mathy, N. Chereau, L. Leenhardt, S. Tezenas du Montcel, C. Buffet
Summary: The study found that different age cutoffs have some impact on the survival and disease progression of RAIR-DTC patients, but age 65 is not a significant predictive factor for survival. Cutoffs at 45 and 75 years old were predictive for overall survival but not progression-free survival.
EUROPEAN JOURNAL OF ENDOCRINOLOGY
(2021)
Article
Otorhinolaryngology
Ping Dong, Li Wang, Yuan Qu, Rui Huang, Lin Li
Summary: The study showed that low-dose radioiodine ablation was as effective as high dose in Chinese patients with differentiated thyroid cancer, with similar success rates between the two groups. This indicates that lower doses of radioiodine may be a suitable treatment option for DTC patients in China.
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
(2021)
Article
Biochemistry & Molecular Biology
Mengdie Yang, Yuzhen Yin, Jiajia Zhang, Wanwan Yi, Jin Liu, Duo Chen, Han Zhang, Xin Fan, Yu Zhang, Mengqin Zhu, Shanshan Qin, Zhongwei Lv, Fei Yu
Summary: The study investigated the relationship between cytokines and differentiated thyroid carcinoma (DTC) and found correlations between cytokines and disease status. Additionally, the study revealed the immunoregulatory effects of radioiodine therapy on serum cytokines in patients with DTC.
JOURNAL OF CELLULAR BIOCHEMISTRY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Hui-di Zhou, Xin-yu Yu, Ying Wei, Zheng-long Zhao, Lili Peng, Yan Li, Nai-cong Lu, Ming-an Yu
Summary: This study evaluated the feasibility, efficiency, and safety of microwave ablation (MWA) for T1N0M0 multifocal papillary thyroid carcinoma (PTC). The results showed that MWA is a safe and effective treatment for T1N0M0 multifocal PTC.
EUROPEAN RADIOLOGY
(2023)
