Article
Medicine, General & Internal
Yilei Yang, Dingkun Aruna, Bin Cheng, Dingkun Xiong, Dong Kuang, Haochen Cui, Si Xiong, Xia Mao, Yunlu Feng, Yuchong Zhao
Summary: This study aimed to evaluate the diagnostic efficacy of immunohistochemistry (IHC) or flow cytometry (FCM) on specimens obtained from EUS-FNB and EUS-FNA in the diagnosis and staging of deep-seated lymphomas. The results showed that compared with EUS-FNA, EUS-FNB yielded better quality tissue samples and higher diagnostic accuracy. The application of FCM improved the diagnostic efficacy of EUS-FNA, but EUS-FNB remained the preferred diagnostic modality in terms of procedure time, accuracy, and cost-effectiveness.
Article
Endocrinology & Metabolism
L. Dal Maso, C. Panato, A. De Paoli, V. Mattioli, D. Serraino, R. Elisei, G. Zoppini, C. Gobitti, E. Borsatti, E. Di Felice, F. Falcini, S. Ferretti, S. Francisci, P. Giorgi Rossi, S. Guzzinati, G. Mazzoleni, D. Pierannunzio, S. Piffer, S. Vaccarella, M. Vicentini, M. Zorzi, S. Franceschi, U. Fedeli
Summary: Evidence of increased diagnostic pressure on the thyroid has been observed in recent decades. A population-based study in North-eastern Italy revealed higher rates of thyroid examinations and treatments for women compared to men. The results highlight the importance of harmonizing practices and reducing unnecessary procedures in certain areas.
JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
(2021)
Article
Health Care Sciences & Services
Michael Osseis, Georges Jammal, Daniel Kazan, Roger Noun
Summary: This study compared the diagnostic accuracy of fine needle aspiration cytology (FNAC) and ultrasound in thyroid nodule diagnosis. The results showed that FNAC had a higher sensitivity than ultrasound, while ultrasound had a higher specificity than FNAC. Combining these two methods can improve diagnostic accuracy.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Endocrinology & Metabolism
Dianna L. Ng, Annemieke van Zante, Ann Griffin, Nancy K. Hills, Britt-Marie Ljung
Summary: This study retrospectively reviewed the UCSF pathology database for thyroid FNABs, analyzing a large cohort of patients with long-term follow-up to determine the risk of thyroid malignancy for different diagnostic categories. The results showed that patients with initial benign or unsatisfactory biopsy results are unlikely to develop thyroid malignancy or die of thyroid cancer, highlighting the high accuracy of FNAB in detecting malignancy.
Article
Otorhinolaryngology
Tobias Todsen, Finn Noe Bennedbaek, Katalin Kiss, Laszlo Hegedus
Summary: Fine needle aspiration biopsy (FNAB) is crucial for evaluating thyroid nodules with suspicious features, and the use of US-guidance is important for real-time visualization of the needle. Collaboration among different specialties is essential for a standardized and meticulous technique to reduce nondiagnostic specimens and false-negative results.
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Zhe Chen, Jia-jia Wang, Dong-ming Guo, Yu-xia Zhai, Zhuo-zhi Dai, Hong-hui Su
Summary: This study aimed to evaluate the diagnostic value of combined fine-needle aspiration (FNA) and core needle biopsy (CNB). The results showed that regardless of nodule size, combined FNA/CNB tended to yield lower proportions of inconclusive results than CNB or FNA alone and exhibited higher performance in diagnosing malignancy. The combined FNA/CNB technique may be a more valuable diagnostic method for nodules ???1.5 cm and nodules with a risk of malignancy than CNB and FNA alone.
Article
Otorhinolaryngology
Seon Min Jung, Hye Ryoung Koo, Ki Seok Jang, Min Sung Chung, Chang Myeon Song, Yong Bae Ji, Jeong Seon Park, Kyung Tae
Summary: Ultrasound-guided CNB is more effective than rFNA for repeat biopsy of thyroid nodules with inconclusive initial FNA results, especially for patients with categories I and III, but showed no significant differences for category IV nodules.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2021)
Article
Pathology
Michael Rechter, Sivan Saraph, Hector Cohen, Ohad Ronen
Summary: This study compared the effects of different needle sizes (23-, 25-, and 27-gauge) on the non-diagnostic (ND) rates of thyroid fine-needle aspiration biopsy (FNAB). The results showed that the 25-gauge needle had a significantly lower ND rate compared to the 27-gauge needle, and increased nodule size was associated with a reduced ND rate.
AMERICAN JOURNAL OF CLINICAL PATHOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Leehi Joo, Dong Gyu Na, Ji-Hoon Kim, Hyobin Seo
Summary: This study compared core needle biopsy (CNB) and repeat fine-needle aspiration (rFNA) in reducing the rates of potential diagnostic surgery and unnecessary surgery for nodules initially diagnosed as atypia/follicular lesions of undetermined significance (AUS/FLUS). CNB was found to be superior to rFNA in reducing the rates of diagnostic surgery and unnecessary surgery.
KOREAN JOURNAL OF RADIOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Ye Wang, Zhenhe Chen, Lin Zhang, Dingrong Zhong, Jinxi Di, Xiaodong Li, Yajuan Lei, Jie Li, Yao Liu, Ruiying Jiang, Lei Cao
Summary: A rapid classification method for malignant and benign thyroid nodules was developed using machine learning with ultrasound guided-fine needle aspiration biopsy (FNAB) samples. The new features generated from pairwise coupling of ions showed better performance than the traditional features, resulting in high accuracy for undetermined patients and especially for those with suspicious for papillary carcinoma diagnosis.
APPLIED SCIENCES-BASEL
(2022)
Review
Endocrinology & Metabolism
Tao Liu, Manisha Tilak, Sara Awad, Joshua Lakoff
Summary: Pain levels during thyroid nodule FNAB are influenced by various factors, including patient-related and procedure-related factors. Nodule calcification, the number of needle passes, the aspiration technique, perpendicular needle placement, and not using safety devices are associated with increased pain. Needle size, biopsy type, operator expertise, and patient education do not appear to be correlated with pain. Subcutaneous lidocaine may provide better pain relief than a topical analgesic.
ENDOCRINE PRACTICE
(2022)
Article
Multidisciplinary Sciences
Saif Bunni, Heikki J. Nieminen
Summary: This study investigates the impact of needle bevel geometry and length on resonance characteristics and deflection magnitude, finding differences in deflection-to-power ratio among needles with different bevel geometries in air and water. The study emphasizes the importance of the relationship between bevel geometry flexural stiffness and insertion media, providing insights for controlling post-puncture cutting action.
SCIENTIFIC REPORTS
(2022)
Article
Biochemistry & Molecular Biology
Giulia Capitoli, Isabella Piga, Vincenzo L'Imperio, Francesca Clerici, Davide Leni, Mattia Garancini, Gabriele Casati, Stefania Galimberti, Fulvio Magni, Fabio Pagni
Summary: Fine-needle aspiration biopsies (FNA) are commonly used to exclude the malignant nature of thyroid nodules, but a significant proportion of cases are indeterminate. A study found that matrix-assisted laser-desorption ionization mass spectrometry imaging (MALDI-MSI) can improve the diagnostic performance of FNA by separating benign and malignant cell areas. However, the performance of the model is affected by poor spectra and noise.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Gastroenterology & Hepatology
Irving Levine, Arvind J. Trindade
Summary: Endoscopic ultrasound tissue acquisition, through EUS-FNA and EUS-FNB, is commonly used for pancreatic mass lesions, subepithelial lesions, and lymph node biopsy. While both methods are safe and offer high diagnostic value, there are potential limitations with EUS-FNA related to cytological aspirations. Comparative trials between EUS-FNA and EUS-FNB for pancreatic mass lesions have shown conflicting results, with the need for further large-scale studies for other types of lesions.
WORLD JOURNAL OF GASTROENTEROLOGY
(2021)
Article
Otorhinolaryngology
Dongbin Ahn, Gil Joon Lee, Jin Ho Sohn
Summary: Percutaneous US-FNAB/CNB offers significant benefits in terms of time and cost over DLB for the diagnosis of LHSCC, with no major complications occurring.
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
(2021)
Article
Biochemistry & Molecular Biology
Wallace Klein Schwengber, Vitor Bock Silveira, Guilherme Moreira Hetzel, Amanda Robaina, Lucieli Ceolin, Marli Teresinha Camelier, Iuri Goemann, Roberta Rigo Dalla Corte, Rafael Selbach Scheffel, Renato Gorga Bandeira de Mello, Ana Luiza Maia, Jose Miguel Dora
Summary: This study found no association between Thr92Ala DIO2 polymorphism and cognitive impairment in older adults.
Article
Respiratory System
Igor Gorski Benedetto, Ravena Maya Cardoso da Silva, Guilherme Moreira Hetzel, Gabriel da Silva Viana, Amanda Reis Guimaraes, Luciano Folador, Vicente Bohrer Brentano, Tiago Severo Garcia, Sergio Pinto Ribeiro, Paulo de Tarso Roth Dalcin, Marcelo Basso Gazzana, Danilo Cortozi Berton
Summary: This study investigates the impact of impaired pulmonary function on patient-centered outcomes after hospital discharge due to severe COVID-19. The findings suggest that patients with a restrictive ventilatory defect exhibit worse respiratory symptoms, health-related quality of life, lung function, and exertional dyspnea compared to those without prior respiratory comorbidities. These results highlight the importance of understanding the long-term consequences of COVID-19 on pulmonary function.
JORNAL BRASILEIRO DE PNEUMOLOGIA
(2023)
Article
Respiratory System
Monica Pruss Pereira, Gisele Branchini, Fernanda Bordignon Nunes, Stephan Altmayer, Guilherme Moreira Hetzel, Iveth Romero, Adalberto Sperb Rubin, Juliessa Florian, Douglas Zaione Nascimento, Guilherme Watte
Summary: Objective: To investigate the impact of pulmonary rehabilitation (PR) on functional outcomes and health-related quality of life (HRQoL) in idiopathic pulmonary fibrosis (IPF) patients placed on a lung transplant waitlist and receiving antifibrotic therapy (AFT). Methods: This was a retrospective observational study of consecutive IPF patients receiving AFT with either pirfenidone or nintedanib (the AFT group) and undergoing PR between January of 2018 and March of 2020. The AFT group and the control group (i.e., IPF patients not receiving AFT) participated in a 12-week PR program consisting of 36 sessions. After having completed the program, the study participants were evaluated for the six-minute walk distance (6MWD) and HRQoL. Pre- and post- PR 6MWD and HRQoL were compared within groups and between groups.
JORNAL BRASILEIRO DE PNEUMOLOGIA
(2023)
Article
Respiratory System
Aline Paula Miozzo, Guilherme Watte, Guilherme Moreira Hetzel, Stephan Altmayer, Douglas Zaione Nascimento, Ermani Cadore, Juliessa Florian, Scheila da Costa Machado, Rodrigo Della Mea Plentz
Summary: This study aimed to identify independent factors associated with the use of oxygen and oxygen flow rate in idiopathic pulmonary fibrosis (IPF) patients undergoing pulmonary rehabilitation (PR) while on a lung transplant waitlist. Functional capacity and health-related quality of life (HRQoL) data were collected before and after 36 sessions of PR, showing that the use of ambulatory oxygen therapy during PR improved functional capacity and HRQoL in patients with IPF.
JORNAL BRASILEIRO DE PNEUMOLOGIA
(2023)
Letter
Respiratory System
Fabiola Adelia Perin, Stephan Altmayer, Douglas Zaione Nascimento, Guilherme Moreira-Hetzel, Spencer Marcantonio Camargo, Bruno Hochhegger, Luzielio Alves Sidney Filho, Jose de Jesus Camargo, Guilherme Watte
JORNAL BRASILEIRO DE PNEUMOLOGIA
(2022)
Letter
Respiratory System
Guilherme Moreira Hetzel, Wallace Klein Schwengber, Diego Corsetti Mondadori, Luiz Felipe Lopes Araujo, Mauricio Guidi Saueressig
JORNAL BRASILEIRO DE PNEUMOLOGIA
(2022)
